STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ccdc91Coiled-coil domain-containing protein 91; Involved in the regulation of membrane traffic through the trans-Golgi network (TGN). Functions in close cooperation with the GGAs in the sorting of hydrolases to lysosomes. (442 aa)    
Predicted Functional Partners:
Gga1
Golgi-associated, gamma adaptin ear-containing, ARF-binding protein 1.
   
 
 0.824
Zbtb40
Zinc finger and BTB domain-containing 40.
    
 
 0.658
Gga2
Golgi associated, gamma adaptin ear containing, ARF binding protein 2, isoform CRA_a.
   
 
 0.591
Eml6
EMAP-like 6.
    
 
 0.587
LOC103694867
ADP-ribosylation factor-binding protein GGA2-like.
    
 
 0.580
Llph
LLP homolog, long-term synaptic facilitation factor.
      
 0.571
Pate2
Prostate and testis-expressed 2.
      
 0.570
Golga5
Golgin subfamily A member 5; Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport.
   
  
 0.540
Erp27
Similar to RIKEN cDNA 1810033M07 (Predicted).
    
 
 0.519
Nckap1
Nck-associated protein 1; Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1 (By similarity). As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity); Belongs to the HEM-1/HEM-2 family.
   
 
 0.500
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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