STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Csn3Kappa-casein; Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk. (178 aa)    
Predicted Functional Partners:
Csn2
Beta-casein; Important role in determination of the surface properties of the casein micelles.
  
  
 0.988
Csn1s1
Alpha-S1-casein; Important role in the capacity of milk to transport calcium phosphate.
   
 
 0.981
Lalba
Alpha-lactalbumin; Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N- acetylglucosamine of the oligosaccharide chains in glycoproteins; Belongs to the glycosyl hydrolase 22 family.
   
  
 0.950
Csn1s2b
Alpha-S2-casein-like B; Important role in the capacity of milk to transport calcium phosphate.
   
  
 0.804
Cym
Prochymosin; Belongs to the peptidase A1 family.
   
  
 0.789
Csn1s2a
Alpha-S2-casein-like A; Important role in the capacity of milk to transport calcium phosphate.
   
  
 0.674
Wap
Whey acidic protein; Could be a protease inhibitor.
   
  
 0.642
Glycam1
Glycosylation-dependent cell adhesion molecule 1; Adhesion molecule that accomplishes cell binding by presenting carbohydrate(s) to the lectin domain of L-selectin; Belongs to the PP3/GlyCAM-1 family.
   
  
 0.634
Btn1a1
Butyrophilin, subfamily 1, member A1.
   
  
 0.624
Lpo
Lactoperoxidase (Predicted).
   
  
 0.581
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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