node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Acbd3 | Golgb1 | ENSRNOP00000074070 | ENSRNOP00000069873 | Golgi resident protein GCP60; Involved in the maintenance of Golgi structure by interacting with giantin, affecting protein transport between the endoplasmic reticulum and Golgi. Involved in hormone-induced steroid biosynthesis in testicular Leydig cells. Recruits PI4KB to the Golgi apparatus membrane; enhances the enzyme activity of PI4KB activity via its membrane recruitment thereby increasing the local concentration of the substrate in the vicinity of the kinase. | Golgin B1. | 0.875 |
Arhgap39 | Golgb1 | ENSRNOP00000051450 | ENSRNOP00000069873 | Rho GTPase-activating protein 39. | Golgin B1. | 0.525 |
Arhgap39 | Tmem35a | ENSRNOP00000051450 | ENSRNOP00000002058 | Rho GTPase-activating protein 39. | Transmembrane protein 35A; A soluble peptide released by shedding may interact with NGFR and modulate sympathetic neurite outgrowth upon chronic activation of the renin-angiotensin system. | 0.683 |
Golga1 | Golga2 | ENSRNOP00000019703 | ENSRNOP00000074890 | Golgi autoantigen, golgin subfamily a, 1 (Predicted). | Golgin subfamily A member 2; Peripheral membrane component of the cis-Golgi stack that acts as a membrane skeleton that maintains the structure of the Golgi apparatus, and as a vesicle thether that facilitates vesicle fusion to the Golgi membrane. Required for normal protein transport from the endoplasmic reticulum to the Golgi apparatus and the cell membrane (By similarity). Together with p115/USO1 and STX5, involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter-connected structure of the Golgi apparatus. Plays a central role in mitotic Go [...] | 0.549 |
Golga1 | Golgb1 | ENSRNOP00000019703 | ENSRNOP00000069873 | Golgi autoantigen, golgin subfamily a, 1 (Predicted). | Golgin B1. | 0.655 |
Golga2 | Golga1 | ENSRNOP00000074890 | ENSRNOP00000019703 | Golgin subfamily A member 2; Peripheral membrane component of the cis-Golgi stack that acts as a membrane skeleton that maintains the structure of the Golgi apparatus, and as a vesicle thether that facilitates vesicle fusion to the Golgi membrane. Required for normal protein transport from the endoplasmic reticulum to the Golgi apparatus and the cell membrane (By similarity). Together with p115/USO1 and STX5, involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter-connected structure of the Golgi apparatus. Plays a central role in mitotic Go [...] | Golgi autoantigen, golgin subfamily a, 1 (Predicted). | 0.549 |
Golga2 | Golgb1 | ENSRNOP00000074890 | ENSRNOP00000069873 | Golgin subfamily A member 2; Peripheral membrane component of the cis-Golgi stack that acts as a membrane skeleton that maintains the structure of the Golgi apparatus, and as a vesicle thether that facilitates vesicle fusion to the Golgi membrane. Required for normal protein transport from the endoplasmic reticulum to the Golgi apparatus and the cell membrane (By similarity). Together with p115/USO1 and STX5, involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter-connected structure of the Golgi apparatus. Plays a central role in mitotic Go [...] | Golgin B1. | 0.998 |
Golga2 | Gosr1 | ENSRNOP00000074890 | ENSRNOP00000068434 | Golgin subfamily A member 2; Peripheral membrane component of the cis-Golgi stack that acts as a membrane skeleton that maintains the structure of the Golgi apparatus, and as a vesicle thether that facilitates vesicle fusion to the Golgi membrane. Required for normal protein transport from the endoplasmic reticulum to the Golgi apparatus and the cell membrane (By similarity). Together with p115/USO1 and STX5, involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter-connected structure of the Golgi apparatus. Plays a central role in mitotic Go [...] | Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an import [...] | 0.997 |
Golga2 | Stx5 | ENSRNOP00000074890 | ENSRNOP00000025664 | Golgin subfamily A member 2; Peripheral membrane component of the cis-Golgi stack that acts as a membrane skeleton that maintains the structure of the Golgi apparatus, and as a vesicle thether that facilitates vesicle fusion to the Golgi membrane. Required for normal protein transport from the endoplasmic reticulum to the Golgi apparatus and the cell membrane (By similarity). Together with p115/USO1 and STX5, involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter-connected structure of the Golgi apparatus. Plays a central role in mitotic Go [...] | Syntaxin-5; Mediates endoplasmic reticulum to Golgi transport. Together with p115/USO1 and GM130/GOLGA2, involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter-connected structure of the Golgi apparatus. | 0.998 |
Golga2 | Uso1 | ENSRNOP00000074890 | ENSRNOP00000003277 | Golgin subfamily A member 2; Peripheral membrane component of the cis-Golgi stack that acts as a membrane skeleton that maintains the structure of the Golgi apparatus, and as a vesicle thether that facilitates vesicle fusion to the Golgi membrane. Required for normal protein transport from the endoplasmic reticulum to the Golgi apparatus and the cell membrane (By similarity). Together with p115/USO1 and STX5, involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter-connected structure of the Golgi apparatus. Plays a central role in mitotic Go [...] | General vesicular transport factor p115; General vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity. Belongs to the VDP/USO1/EDE1 family. | 0.919 |
Golgb1 | Acbd3 | ENSRNOP00000069873 | ENSRNOP00000074070 | Golgin B1. | Golgi resident protein GCP60; Involved in the maintenance of Golgi structure by interacting with giantin, affecting protein transport between the endoplasmic reticulum and Golgi. Involved in hormone-induced steroid biosynthesis in testicular Leydig cells. Recruits PI4KB to the Golgi apparatus membrane; enhances the enzyme activity of PI4KB activity via its membrane recruitment thereby increasing the local concentration of the substrate in the vicinity of the kinase. | 0.875 |
Golgb1 | Arhgap39 | ENSRNOP00000069873 | ENSRNOP00000051450 | Golgin B1. | Rho GTPase-activating protein 39. | 0.525 |
Golgb1 | Golga1 | ENSRNOP00000069873 | ENSRNOP00000019703 | Golgin B1. | Golgi autoantigen, golgin subfamily a, 1 (Predicted). | 0.655 |
Golgb1 | Golga2 | ENSRNOP00000069873 | ENSRNOP00000074890 | Golgin B1. | Golgin subfamily A member 2; Peripheral membrane component of the cis-Golgi stack that acts as a membrane skeleton that maintains the structure of the Golgi apparatus, and as a vesicle thether that facilitates vesicle fusion to the Golgi membrane. Required for normal protein transport from the endoplasmic reticulum to the Golgi apparatus and the cell membrane (By similarity). Together with p115/USO1 and STX5, involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter-connected structure of the Golgi apparatus. Plays a central role in mitotic Go [...] | 0.998 |
Golgb1 | Gosr1 | ENSRNOP00000069873 | ENSRNOP00000068434 | Golgin B1. | Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an import [...] | 0.995 |
Golgb1 | Sec31b | ENSRNOP00000069873 | ENSRNOP00000038038 | Golgin B1. | SEC31 homolog B, COPII coat complex component. | 0.532 |
Golgb1 | Stx5 | ENSRNOP00000069873 | ENSRNOP00000025664 | Golgin B1. | Syntaxin-5; Mediates endoplasmic reticulum to Golgi transport. Together with p115/USO1 and GM130/GOLGA2, involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter-connected structure of the Golgi apparatus. | 0.995 |
Golgb1 | Tmem35a | ENSRNOP00000069873 | ENSRNOP00000002058 | Golgin B1. | Transmembrane protein 35A; A soluble peptide released by shedding may interact with NGFR and modulate sympathetic neurite outgrowth upon chronic activation of the renin-angiotensin system. | 0.705 |
Golgb1 | Tmem39b | ENSRNOP00000069873 | ENSRNOP00000032295 | Golgin B1. | Transmembrane protein 39B. | 0.539 |
Golgb1 | Uso1 | ENSRNOP00000069873 | ENSRNOP00000003277 | Golgin B1. | General vesicular transport factor p115; General vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity. Belongs to the VDP/USO1/EDE1 family. | 0.997 |