node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Bfar | Birc6 | ENSRNOP00000004217 | ENSRNOP00000070913 | Bifunctional apoptosis regulator; Apoptosis regulator. Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors (By similarity). | Baculoviral IAP repeat-containing 6. | 0.502 |
Bfar | Bnip1 | ENSRNOP00000004217 | ENSRNOP00000028173 | Bifunctional apoptosis regulator; Apoptosis regulator. Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors (By similarity). | Vesicle transport protein SEC20; As part of a SNARE complex may be involved in endoplasmic reticulum membranes fusion and be required for the maintenance of endoplasmic reticulum organization. Plays also a role in apoptosis. It is for instance required for endoplasmic reticulum stress-induced apoptosis. As a substrate of RNF185 interacting with SQSTM1, might also be involved in mitochondrial autophagy; Belongs to the SEC20 family. | 0.440 |
Bfar | Card6 | ENSRNOP00000004217 | ENSRNOP00000068759 | Bifunctional apoptosis regulator; Apoptosis regulator. Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors (By similarity). | Caspase recruitment domain family, member 6. | 0.439 |
Bfar | Cideb | ENSRNOP00000004217 | ENSRNOP00000027612 | Bifunctional apoptosis regulator; Apoptosis regulator. Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors (By similarity). | Cell death-inducing DNAation factor, alpha subunit-like effector B (Predicted), isoform CRA_a. | 0.498 |
Bfar | Cradd | ENSRNOP00000004217 | ENSRNOP00000062865 | Bifunctional apoptosis regulator; Apoptosis regulator. Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors (By similarity). | CASP2 and RIPK1 domain containing adaptor with death domain (Predicted), isoform CRA_a. | 0.575 |
Bfar | Nol3 | ENSRNOP00000004217 | ENSRNOP00000020908 | Bifunctional apoptosis regulator; Apoptosis regulator. Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors (By similarity). | Nucleolar protein 3; Apoptosis repressor that blocks multiple modes of cell death. Inhibits extrinsic apoptotic pathways through two different ways. Firstly by interacting with FAS and FADD upon FAS activation blocking death-inducing signaling complex (DISC) assembly. Secondly by interacting with CASP8 in a mitochondria localization- and phosphorylation-dependent manner, limiting the amount of soluble CASP8 available for DISC-mediated activation. Inhibits intrinsic apoptotic pathway in response to a wide range of stresses, through its interaction with BAX resulting in BAX inactivation, [...] | 0.472 |
Bfar | Tmbim6 | ENSRNOP00000004217 | ENSRNOP00000069944 | Bifunctional apoptosis regulator; Apoptosis regulator. Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors (By similarity). | Bax inhibitor 1; Suppressor of apoptosis. Modulates unfolded protein response signaling. Modulates ER calcium homeostasis by acting as a calcium-leak channel. Negatively regulates autophagy and autophagosome formation, especially during periods of nutrient deprivation, and reduces cell survival during starvation; Belongs to the BI1 family. | 0.507 |
Bfar | Tnfaip8l1 | ENSRNOP00000004217 | ENSRNOP00000065435 | Bifunctional apoptosis regulator; Apoptosis regulator. Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors (By similarity). | TNF alpha-induced protein 8-like 1. | 0.431 |
Bfar | Tp53bp2 | ENSRNOP00000004217 | ENSRNOP00000004330 | Bifunctional apoptosis regulator; Apoptosis regulator. Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors (By similarity). | Tumor protein p53-binding protein, 2. | 0.477 |
Bfar | Zfp105 | ENSRNOP00000004217 | ENSRNOP00000042236 | Bifunctional apoptosis regulator; Apoptosis regulator. Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors (By similarity). | Zinc finger protein 105, isoform CRA_a. | 0.572 |
Birc6 | Bfar | ENSRNOP00000070913 | ENSRNOP00000004217 | Baculoviral IAP repeat-containing 6. | Bifunctional apoptosis regulator; Apoptosis regulator. Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors (By similarity). | 0.502 |
Bnip1 | Bfar | ENSRNOP00000028173 | ENSRNOP00000004217 | Vesicle transport protein SEC20; As part of a SNARE complex may be involved in endoplasmic reticulum membranes fusion and be required for the maintenance of endoplasmic reticulum organization. Plays also a role in apoptosis. It is for instance required for endoplasmic reticulum stress-induced apoptosis. As a substrate of RNF185 interacting with SQSTM1, might also be involved in mitochondrial autophagy; Belongs to the SEC20 family. | Bifunctional apoptosis regulator; Apoptosis regulator. Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors (By similarity). | 0.440 |
Bnip1 | Card6 | ENSRNOP00000028173 | ENSRNOP00000068759 | Vesicle transport protein SEC20; As part of a SNARE complex may be involved in endoplasmic reticulum membranes fusion and be required for the maintenance of endoplasmic reticulum organization. Plays also a role in apoptosis. It is for instance required for endoplasmic reticulum stress-induced apoptosis. As a substrate of RNF185 interacting with SQSTM1, might also be involved in mitochondrial autophagy; Belongs to the SEC20 family. | Caspase recruitment domain family, member 6. | 0.510 |
Card6 | Bfar | ENSRNOP00000068759 | ENSRNOP00000004217 | Caspase recruitment domain family, member 6. | Bifunctional apoptosis regulator; Apoptosis regulator. Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors (By similarity). | 0.439 |
Card6 | Bnip1 | ENSRNOP00000068759 | ENSRNOP00000028173 | Caspase recruitment domain family, member 6. | Vesicle transport protein SEC20; As part of a SNARE complex may be involved in endoplasmic reticulum membranes fusion and be required for the maintenance of endoplasmic reticulum organization. Plays also a role in apoptosis. It is for instance required for endoplasmic reticulum stress-induced apoptosis. As a substrate of RNF185 interacting with SQSTM1, might also be involved in mitochondrial autophagy; Belongs to the SEC20 family. | 0.510 |
Card6 | Cideb | ENSRNOP00000068759 | ENSRNOP00000027612 | Caspase recruitment domain family, member 6. | Cell death-inducing DNAation factor, alpha subunit-like effector B (Predicted), isoform CRA_a. | 0.473 |
Card6 | Tp53bp2 | ENSRNOP00000068759 | ENSRNOP00000004330 | Caspase recruitment domain family, member 6. | Tumor protein p53-binding protein, 2. | 0.535 |
Cideb | Bfar | ENSRNOP00000027612 | ENSRNOP00000004217 | Cell death-inducing DNAation factor, alpha subunit-like effector B (Predicted), isoform CRA_a. | Bifunctional apoptosis regulator; Apoptosis regulator. Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors (By similarity). | 0.498 |
Cideb | Card6 | ENSRNOP00000027612 | ENSRNOP00000068759 | Cell death-inducing DNAation factor, alpha subunit-like effector B (Predicted), isoform CRA_a. | Caspase recruitment domain family, member 6. | 0.473 |
Cideb | Nol3 | ENSRNOP00000027612 | ENSRNOP00000020908 | Cell death-inducing DNAation factor, alpha subunit-like effector B (Predicted), isoform CRA_a. | Nucleolar protein 3; Apoptosis repressor that blocks multiple modes of cell death. Inhibits extrinsic apoptotic pathways through two different ways. Firstly by interacting with FAS and FADD upon FAS activation blocking death-inducing signaling complex (DISC) assembly. Secondly by interacting with CASP8 in a mitochondria localization- and phosphorylation-dependent manner, limiting the amount of soluble CASP8 available for DISC-mediated activation. Inhibits intrinsic apoptotic pathway in response to a wide range of stresses, through its interaction with BAX resulting in BAX inactivation, [...] | 0.411 |