Export your current network:
... as a bitmap image:
file format is 'PNG': portable network graphic
... as a high-resolution bitmap:
same PNG format, but at higher resolution
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cbl | Egfr | ENSRNOP00000063226 | ENSRNOP00000006087 | Cbl proto-oncogene. | Receptor protein-tyrosine kinase. | 0.999 |
Cbl | Gab1 | ENSRNOP00000063226 | ENSRNOP00000071006 | Cbl proto-oncogene. | GRB2-associated-binding protein 1. | 0.633 |
Cbl | Grb2 | ENSRNOP00000063226 | ENSRNOP00000005347 | Cbl proto-oncogene. | Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. | 0.999 |
Cbl | Irs1 | ENSRNOP00000063226 | ENSRNOP00000019579 | Cbl proto-oncogene. | Insulin receptor substrate 1; May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit. | 0.597 |
Cbl | Lcp2 | ENSRNOP00000063226 | ENSRNOP00000050879 | Cbl proto-oncogene. | Lymphocyte cytosolic protein 2. | 0.890 |
Cbl | Ptpn11 | ENSRNOP00000063226 | ENSRNOP00000041842 | Cbl proto-oncogene. | Tyrosine-protein phosphatase non-receptor type 11; Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Positively regulates MAPK signal transduction pathway. Dephosphorylates GAB1, ARHGAP35 and EGFR. Dephosphorylates ROCK2 at 'Tyr-722' resulting in stimulatation of its RhoA binding activity. Dephosphorylates CDC73. | 0.916 |
Cbl | Shc1 | ENSRNOP00000063226 | ENSRNOP00000028038 | Cbl proto-oncogene. | SHC-transforming protein 1; Signaling adapter that couples activated growth factor receptors to signaling pathways. Participates in a signaling cascade initiated by activated KIT and KITLG/SCF. Participates in signaling downstream of the angiopoietin receptor TEK/TIE2, and plays a role in the regulation of endothelial cell migration and sprouting angiogenesis (By similarity). | 0.946 |
Cbl | Sos1 | ENSRNOP00000063226 | ENSRNOP00000009359 | Cbl proto-oncogene. | SOS Ras/Rac guanine nucleotide exchange factor 1. | 0.787 |
Cbl | Sos2 | ENSRNOP00000063226 | ENSRNOP00000006425 | Cbl proto-oncogene. | SOS Ras/Rho guanine nucleotide exchange factor 2. | 0.565 |
Cbl | Vav1 | ENSRNOP00000063226 | ENSRNOP00000064264 | Cbl proto-oncogene. | Proto-oncogene vav; Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation. | 0.993 |
Egfr | Cbl | ENSRNOP00000006087 | ENSRNOP00000063226 | Receptor protein-tyrosine kinase. | Cbl proto-oncogene. | 0.999 |
Egfr | Gab1 | ENSRNOP00000006087 | ENSRNOP00000071006 | Receptor protein-tyrosine kinase. | GRB2-associated-binding protein 1. | 0.997 |
Egfr | Grb2 | ENSRNOP00000006087 | ENSRNOP00000005347 | Receptor protein-tyrosine kinase. | Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. | 0.999 |
Egfr | Irs1 | ENSRNOP00000006087 | ENSRNOP00000019579 | Receptor protein-tyrosine kinase. | Insulin receptor substrate 1; May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit. | 0.891 |
Egfr | Ptpn11 | ENSRNOP00000006087 | ENSRNOP00000041842 | Receptor protein-tyrosine kinase. | Tyrosine-protein phosphatase non-receptor type 11; Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Positively regulates MAPK signal transduction pathway. Dephosphorylates GAB1, ARHGAP35 and EGFR. Dephosphorylates ROCK2 at 'Tyr-722' resulting in stimulatation of its RhoA binding activity. Dephosphorylates CDC73. | 0.999 |
Egfr | Shc1 | ENSRNOP00000006087 | ENSRNOP00000028038 | Receptor protein-tyrosine kinase. | SHC-transforming protein 1; Signaling adapter that couples activated growth factor receptors to signaling pathways. Participates in a signaling cascade initiated by activated KIT and KITLG/SCF. Participates in signaling downstream of the angiopoietin receptor TEK/TIE2, and plays a role in the regulation of endothelial cell migration and sprouting angiogenesis (By similarity). | 0.999 |
Egfr | Sos1 | ENSRNOP00000006087 | ENSRNOP00000009359 | Receptor protein-tyrosine kinase. | SOS Ras/Rac guanine nucleotide exchange factor 1. | 0.998 |
Egfr | Sos2 | ENSRNOP00000006087 | ENSRNOP00000006425 | Receptor protein-tyrosine kinase. | SOS Ras/Rho guanine nucleotide exchange factor 2. | 0.991 |
Egfr | Vav1 | ENSRNOP00000006087 | ENSRNOP00000064264 | Receptor protein-tyrosine kinase. | Proto-oncogene vav; Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation. | 0.706 |
Gab1 | Cbl | ENSRNOP00000071006 | ENSRNOP00000063226 | GRB2-associated-binding protein 1. | Cbl proto-oncogene. | 0.633 |
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