| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cd79a | Cd79b | ENSRNOP00000027254 | ENSRNOP00000015977 | Ig-like domain-containing protein. | B29/Ig-beta/CD79b. | 0.999 |
| Cd79a | Jchain | ENSRNOP00000027254 | ENSRNOP00000004866 | Ig-like domain-containing protein. | Immunoglobulin joining chain. | 0.884 |
| Cd79a | Lime1 | ENSRNOP00000027254 | ENSRNOP00000019545 | Ig-like domain-containing protein. | Similar to Lck-interacting transmembrane adaptor protein LIME (Predicted), isoform CRA_b. | 0.720 |
| Cd79a | Pigr | ENSRNOP00000027254 | ENSRNOP00000073662 | Ig-like domain-containing protein. | Polymeric immunoglobulin receptor; This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment. | 0.790 |
| Cd79a | Syk | ENSRNOP00000027254 | ENSRNOP00000016942 | Ig-like domain-containing protein. | Tyrosine-protein kinase SYK; Non-receptor tyrosine kinase which mediates signal transduction downstream of a variety of transmembrane receptors including classical immunoreceptors like the B-cell receptor (BCR). Regulates several biological processes including innate and adaptive immunity, cell adhesion, osteoclast maturation, platelet activation and vascular development. Assembles into signaling complexes with activated receptors at the plasma membrane via interaction between its SH2 domains and the receptor tyrosine-phosphorylated ITAM domains. The association with the receptor can a [...] | 0.771 |
| Cd79b | Cd79a | ENSRNOP00000015977 | ENSRNOP00000027254 | B29/Ig-beta/CD79b. | Ig-like domain-containing protein. | 0.999 |
| Cd79b | Fcgrt | ENSRNOP00000015977 | ENSRNOP00000027944 | B29/Ig-beta/CD79b. | IgG receptor FcRn large subunit p51; Cell surface receptor that transfers passive humoral immunity from the mother to the newborn. Binds to the Fc region of monomeric immunoglobulin gamma and mediates its selective uptake from milk. IgG in the milk is bound at the apical surface of the intestinal epithelium. The resultant FcRn-IgG complexes are transcytosed across the intestinal epithelium and IgG is released from FcRn into blood or tissue fluids. Throughout life, contributes to effective humoral immunity by recycling IgG and extending its half-life in the circulation. Mechanistically, [...] | 0.472 |
| Cd79b | Jchain | ENSRNOP00000015977 | ENSRNOP00000004866 | B29/Ig-beta/CD79b. | Immunoglobulin joining chain. | 0.880 |
| Cd79b | Lime1 | ENSRNOP00000015977 | ENSRNOP00000019545 | B29/Ig-beta/CD79b. | Similar to Lck-interacting transmembrane adaptor protein LIME (Predicted), isoform CRA_b. | 0.724 |
| Cd79b | Pigr | ENSRNOP00000015977 | ENSRNOP00000073662 | B29/Ig-beta/CD79b. | Polymeric immunoglobulin receptor; This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment. | 0.779 |
| Cd79b | Syk | ENSRNOP00000015977 | ENSRNOP00000016942 | B29/Ig-beta/CD79b. | Tyrosine-protein kinase SYK; Non-receptor tyrosine kinase which mediates signal transduction downstream of a variety of transmembrane receptors including classical immunoreceptors like the B-cell receptor (BCR). Regulates several biological processes including innate and adaptive immunity, cell adhesion, osteoclast maturation, platelet activation and vascular development. Assembles into signaling complexes with activated receptors at the plasma membrane via interaction between its SH2 domains and the receptor tyrosine-phosphorylated ITAM domains. The association with the receptor can a [...] | 0.781 |
| Fcgrt | Cd79b | ENSRNOP00000027944 | ENSRNOP00000015977 | IgG receptor FcRn large subunit p51; Cell surface receptor that transfers passive humoral immunity from the mother to the newborn. Binds to the Fc region of monomeric immunoglobulin gamma and mediates its selective uptake from milk. IgG in the milk is bound at the apical surface of the intestinal epithelium. The resultant FcRn-IgG complexes are transcytosed across the intestinal epithelium and IgG is released from FcRn into blood or tissue fluids. Throughout life, contributes to effective humoral immunity by recycling IgG and extending its half-life in the circulation. Mechanistically, [...] | B29/Ig-beta/CD79b. | 0.472 |
| Fcgrt | Il2 | ENSRNOP00000027944 | ENSRNOP00000023327 | IgG receptor FcRn large subunit p51; Cell surface receptor that transfers passive humoral immunity from the mother to the newborn. Binds to the Fc region of monomeric immunoglobulin gamma and mediates its selective uptake from milk. IgG in the milk is bound at the apical surface of the intestinal epithelium. The resultant FcRn-IgG complexes are transcytosed across the intestinal epithelium and IgG is released from FcRn into blood or tissue fluids. Throughout life, contributes to effective humoral immunity by recycling IgG and extending its half-life in the circulation. Mechanistically, [...] | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. | 0.536 |
| Fcgrt | Pigr | ENSRNOP00000027944 | ENSRNOP00000073662 | IgG receptor FcRn large subunit p51; Cell surface receptor that transfers passive humoral immunity from the mother to the newborn. Binds to the Fc region of monomeric immunoglobulin gamma and mediates its selective uptake from milk. IgG in the milk is bound at the apical surface of the intestinal epithelium. The resultant FcRn-IgG complexes are transcytosed across the intestinal epithelium and IgG is released from FcRn into blood or tissue fluids. Throughout life, contributes to effective humoral immunity by recycling IgG and extending its half-life in the circulation. Mechanistically, [...] | Polymeric immunoglobulin receptor; This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment. | 0.708 |
| Il2 | Fcgrt | ENSRNOP00000023327 | ENSRNOP00000027944 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. | IgG receptor FcRn large subunit p51; Cell surface receptor that transfers passive humoral immunity from the mother to the newborn. Binds to the Fc region of monomeric immunoglobulin gamma and mediates its selective uptake from milk. IgG in the milk is bound at the apical surface of the intestinal epithelium. The resultant FcRn-IgG complexes are transcytosed across the intestinal epithelium and IgG is released from FcRn into blood or tissue fluids. Throughout life, contributes to effective humoral immunity by recycling IgG and extending its half-life in the circulation. Mechanistically, [...] | 0.536 |
| Il2 | Jchain | ENSRNOP00000023327 | ENSRNOP00000004866 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. | Immunoglobulin joining chain. | 0.767 |
| Il2 | Piga | ENSRNOP00000023327 | ENSRNOP00000045342 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. | Phosphatidylinositol glycan anchor biosynthesis, class A. | 0.453 |
| Il2 | Pigr | ENSRNOP00000023327 | ENSRNOP00000073662 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. | Polymeric immunoglobulin receptor; This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment. | 0.792 |
| Jchain | Cd79a | ENSRNOP00000004866 | ENSRNOP00000027254 | Immunoglobulin joining chain. | Ig-like domain-containing protein. | 0.884 |
| Jchain | Cd79b | ENSRNOP00000004866 | ENSRNOP00000015977 | Immunoglobulin joining chain. | B29/Ig-beta/CD79b. | 0.880 |
STRING v12.5 is now available!
