STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Fignl1Fidgetin-like protein 1; Involved in DNA double-strand break (DBS) repair via homologous recombination (HR). Recruited at DSB sites independently of BRCA2, RAD51 and RAD51 paralogs in a H2AX-dependent manner. May regulate osteoblast proliferation and differentiation (By similarity). May play a role in the control of male meiosis dynamic (By similarity). (677 aa)    
Predicted Functional Partners:
Exo1
Exonuclease 1.
  
  
 0.930
Ubxn7
UBX domain-containing protein 7.
   
 
 0.802
LOC100911374
UBX domain-containing protein 7-like.
   
 
 0.802
Ercc6l
ERCC excision repair 6-like, spindle assembly checkpoint helicase.
   
 
 0.799
Rad54l
Rad54l protein.
   
 
 0.781
Ncaph
Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.
   
 
 0.713
Spata48
Spermatogenesis-associated 48.
   
  
 0.711
Zpbp
Zona pellucida binding protein, isoform CRA_b.
      
 0.693
Kntc1
Kinetochore associated 1 (Predicted).
   
  
 0.674
Spidr
Scaffold protein involved in DNA repair.
    
 
 0.660
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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