STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Il24Interleukin-24; Has antiproliferative properties on melanoma cells and may contribute to terminal cell differentiation. (183 aa)    
Predicted Functional Partners:
Il20ra
Interleukin 20 receptor, alpha (Predicted).
     
 0.995
Il22ra1
Interleukin 22 receptor subunit alpha 1.
    
 0.994
Il20rb
Interleukin 20 receptor beta IL-20R2.
     
 0.956
Il19
Interleukin 19.
  
 
0.956
Il20
Interleukin 20.
  
 
0.941
Il10rb
Similar to class II cytokine receptor 4 (Predicted), isoform CRA_a.
     
 0.863
Il22ra2
Interleukin-22 receptor subunit alpha-2; Receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses; Belongs to the type II cytokine receptor family.
   
 
 0.797
Il10ra
Interleukin 10 receptor subunit alpha.
   
 
 0.769
Il22
Similar to TIF alpha protein (Predicted).
   
  
 0.750
Il23r
Interleukin 23 receptor.
     
 0.744
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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