node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A1bg | Ahsg | ENSRNOP00000006273 | ENSRNOP00000073898 | Alpha-1B-glycoprotein. | Alpha-2-HS-glycoprotein; Could inhibit both insulin-receptor tyrosine kinase activity and insulin-stimulated receptor autophosphorylation and, concomitantly, antagonize the mitogenic effect of the hormone in cultured rat hepatoma cells. | 0.616 |
A1bg | Ambp | ENSRNOP00000006273 | ENSRNOP00000009248 | Alpha-1B-glycoprotein. | Inter-alpha-trypsin inhibitor light chain; Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization (By similarity); In the N-terminal section; belongs to the calycin superfamily. Lipocalin family. | 0.588 |
A1bg | Azgp1 | ENSRNOP00000006273 | ENSRNOP00000001801 | Alpha-1B-glycoprotein. | Zinc-alpha-2-glycoprotein; Stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers. Belongs to the MHC class I family. | 0.548 |
A1bg | Crisp3 | ENSRNOP00000006273 | ENSRNOP00000018162 | Alpha-1B-glycoprotein. | Cysteine-rich secretory protein 1; This protein is supposed to help spermatozoa undergo functional maturation while they move from the testis to the ductus deferens; Belongs to the CRISP family. | 0.783 |
A1bg | Gc | ENSRNOP00000006273 | ENSRNOP00000004174 | Alpha-1B-glycoprotein. | Vitamin D-binding protein; Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation. | 0.633 |
A1bg | Hp | ENSRNOP00000006273 | ENSRNOP00000020196 | Alpha-1B-glycoprotein. | Haptoglobin alpha chain; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pat [...] | 0.605 |
A1bg | Hpx | ENSRNOP00000006273 | ENSRNOP00000024710 | Alpha-1B-glycoprotein. | Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. | 0.628 |
A1bg | Lrg1 | ENSRNOP00000006273 | ENSRNOP00000065771 | Alpha-1B-glycoprotein. | Leucine-rich alpha-2-glycoprotein 1. | 0.569 |
A1bg | Serpina1 | ENSRNOP00000006273 | ENSRNOP00000070937 | Alpha-1B-glycoprotein. | Alpha-1-antiproteinase; Inhibitor of serine proteases. The primary target is elastase, but also has a moderate affinity for plasmin and thrombin; Belongs to the serpin family. | 0.540 |
A1bg | Tf | ENSRNOP00000006273 | ENSRNOP00000012725 | Alpha-1B-glycoprotein. | Serotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. | 0.641 |
Ahsg | A1bg | ENSRNOP00000073898 | ENSRNOP00000006273 | Alpha-2-HS-glycoprotein; Could inhibit both insulin-receptor tyrosine kinase activity and insulin-stimulated receptor autophosphorylation and, concomitantly, antagonize the mitogenic effect of the hormone in cultured rat hepatoma cells. | Alpha-1B-glycoprotein. | 0.616 |
Ahsg | Ambp | ENSRNOP00000073898 | ENSRNOP00000009248 | Alpha-2-HS-glycoprotein; Could inhibit both insulin-receptor tyrosine kinase activity and insulin-stimulated receptor autophosphorylation and, concomitantly, antagonize the mitogenic effect of the hormone in cultured rat hepatoma cells. | Inter-alpha-trypsin inhibitor light chain; Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization (By similarity); In the N-terminal section; belongs to the calycin superfamily. Lipocalin family. | 0.924 |
Ahsg | Azgp1 | ENSRNOP00000073898 | ENSRNOP00000001801 | Alpha-2-HS-glycoprotein; Could inhibit both insulin-receptor tyrosine kinase activity and insulin-stimulated receptor autophosphorylation and, concomitantly, antagonize the mitogenic effect of the hormone in cultured rat hepatoma cells. | Zinc-alpha-2-glycoprotein; Stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers. Belongs to the MHC class I family. | 0.671 |
Ahsg | Gc | ENSRNOP00000073898 | ENSRNOP00000004174 | Alpha-2-HS-glycoprotein; Could inhibit both insulin-receptor tyrosine kinase activity and insulin-stimulated receptor autophosphorylation and, concomitantly, antagonize the mitogenic effect of the hormone in cultured rat hepatoma cells. | Vitamin D-binding protein; Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation. | 0.951 |
Ahsg | Hp | ENSRNOP00000073898 | ENSRNOP00000020196 | Alpha-2-HS-glycoprotein; Could inhibit both insulin-receptor tyrosine kinase activity and insulin-stimulated receptor autophosphorylation and, concomitantly, antagonize the mitogenic effect of the hormone in cultured rat hepatoma cells. | Haptoglobin alpha chain; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pat [...] | 0.750 |
Ahsg | Hpx | ENSRNOP00000073898 | ENSRNOP00000024710 | Alpha-2-HS-glycoprotein; Could inhibit both insulin-receptor tyrosine kinase activity and insulin-stimulated receptor autophosphorylation and, concomitantly, antagonize the mitogenic effect of the hormone in cultured rat hepatoma cells. | Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. | 0.876 |
Ahsg | Lrg1 | ENSRNOP00000073898 | ENSRNOP00000065771 | Alpha-2-HS-glycoprotein; Could inhibit both insulin-receptor tyrosine kinase activity and insulin-stimulated receptor autophosphorylation and, concomitantly, antagonize the mitogenic effect of the hormone in cultured rat hepatoma cells. | Leucine-rich alpha-2-glycoprotein 1. | 0.432 |
Ahsg | Serpina1 | ENSRNOP00000073898 | ENSRNOP00000070937 | Alpha-2-HS-glycoprotein; Could inhibit both insulin-receptor tyrosine kinase activity and insulin-stimulated receptor autophosphorylation and, concomitantly, antagonize the mitogenic effect of the hormone in cultured rat hepatoma cells. | Alpha-1-antiproteinase; Inhibitor of serine proteases. The primary target is elastase, but also has a moderate affinity for plasmin and thrombin; Belongs to the serpin family. | 0.932 |
Ahsg | Tf | ENSRNOP00000073898 | ENSRNOP00000012725 | Alpha-2-HS-glycoprotein; Could inhibit both insulin-receptor tyrosine kinase activity and insulin-stimulated receptor autophosphorylation and, concomitantly, antagonize the mitogenic effect of the hormone in cultured rat hepatoma cells. | Serotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. | 0.742 |
Ambp | A1bg | ENSRNOP00000009248 | ENSRNOP00000006273 | Inter-alpha-trypsin inhibitor light chain; Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization (By similarity); In the N-terminal section; belongs to the calycin superfamily. Lipocalin family. | Alpha-1B-glycoprotein. | 0.588 |