| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cd2 | Cd244 | ENSRNOP00000021268 | ENSRNOP00000006266 | T-cell surface antigen CD2; CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. | Natural killer cell receptor 2B4; Modulate other receptor-ligand interactions to enhance leukocyte activation. | 0.674 |
| Cd2 | Cd34 | ENSRNOP00000021268 | ENSRNOP00000074896 | T-cell surface antigen CD2; CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. | CD34 antigen (Predicted). | 0.591 |
| Cd2 | Cd4 | ENSRNOP00000021268 | ENSRNOP00000021915 | T-cell surface antigen CD2; CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | 0.877 |
| Cd2 | Cd48 | ENSRNOP00000021268 | ENSRNOP00000006306 | T-cell surface antigen CD2; CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. | CD48 antigen; Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation. | 0.823 |
| Cd2 | Cd52 | ENSRNOP00000021268 | ENSRNOP00000020688 | T-cell surface antigen CD2; CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. | CAMPATH-1 antigen; May play a role in carrying and orienting carbohydrate, as well as having a more specific role. | 0.809 |
| Cd2 | Cd53 | ENSRNOP00000021268 | ENSRNOP00000024344 | T-cell surface antigen CD2; CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. | Leukocyte surface antigen CD53; Required for efficient formation of myofibers in regenerating muscle at the level of cell fusion. May be involved in growth regulation in hematopoietic cells (By similarity); Belongs to the tetraspanin (TM4SF) family. | 0.603 |
| Cd2 | Ly9 | ENSRNOP00000021268 | ENSRNOP00000036230 | T-cell surface antigen CD2; CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. | Lymphocyte antigen 9. | 0.527 |
| Cd2 | Ptprc | ENSRNOP00000021268 | ENSRNOP00000063859 | T-cell surface antigen CD2; CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. | Receptor-type tyrosine-protein phosphatase C; Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN (By similarity). Dephosphorylates LYN, and thereby modulates LYN activity (By similarity). | 0.733 |
| Cd244 | Cd2 | ENSRNOP00000006266 | ENSRNOP00000021268 | Natural killer cell receptor 2B4; Modulate other receptor-ligand interactions to enhance leukocyte activation. | T-cell surface antigen CD2; CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. | 0.674 |
| Cd244 | Cd4 | ENSRNOP00000006266 | ENSRNOP00000021915 | Natural killer cell receptor 2B4; Modulate other receptor-ligand interactions to enhance leukocyte activation. | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | 0.763 |
| Cd244 | Cd48 | ENSRNOP00000006266 | ENSRNOP00000006306 | Natural killer cell receptor 2B4; Modulate other receptor-ligand interactions to enhance leukocyte activation. | CD48 antigen; Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation. | 0.999 |
| Cd244 | Ly9 | ENSRNOP00000006266 | ENSRNOP00000036230 | Natural killer cell receptor 2B4; Modulate other receptor-ligand interactions to enhance leukocyte activation. | Lymphocyte antigen 9. | 0.641 |
| Cd244 | Ptprc | ENSRNOP00000006266 | ENSRNOP00000063859 | Natural killer cell receptor 2B4; Modulate other receptor-ligand interactions to enhance leukocyte activation. | Receptor-type tyrosine-protein phosphatase C; Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN (By similarity). Dephosphorylates LYN, and thereby modulates LYN activity (By similarity). | 0.555 |
| Cd34 | Cd2 | ENSRNOP00000074896 | ENSRNOP00000021268 | CD34 antigen (Predicted). | T-cell surface antigen CD2; CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. | 0.591 |
| Cd34 | Cd4 | ENSRNOP00000074896 | ENSRNOP00000021915 | CD34 antigen (Predicted). | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | 0.888 |
| Cd34 | Cd48 | ENSRNOP00000074896 | ENSRNOP00000006306 | CD34 antigen (Predicted). | CD48 antigen; Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation. | 0.706 |
| Cd34 | Mpp3 | ENSRNOP00000074896 | ENSRNOP00000071372 | CD34 antigen (Predicted). | MAGUK p55 subfamily member 3. | 0.588 |
| Cd34 | Ptprc | ENSRNOP00000074896 | ENSRNOP00000063859 | CD34 antigen (Predicted). | Receptor-type tyrosine-protein phosphatase C; Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN (By similarity). Dephosphorylates LYN, and thereby modulates LYN activity (By similarity). | 0.925 |
| Cd4 | Cd2 | ENSRNOP00000021915 | ENSRNOP00000021268 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | T-cell surface antigen CD2; CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. | 0.877 |
| Cd4 | Cd244 | ENSRNOP00000021915 | ENSRNOP00000006266 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | Natural killer cell receptor 2B4; Modulate other receptor-ligand interactions to enhance leukocyte activation. | 0.763 |
