Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
JkampSimilar to RIKEN cDNA 1200003C05 (Predicted). (311 aa)    
Predicted Functional Partners:
Ccdc175
Coiled-coil domain-containing protein 175.
      
 0.799
Ap3s1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
   
  
 0.522
Snx24
Sorting nexin-24; May be involved in several stages of intracellular trafficking.
   
  
 0.484
Ascc1
Activating signal cointegrator 1 complex subunit 1, isoform CRA_b.
      
 0.484
Themis2
Thymocyte selection-associated family member 2.
      
 0.480
Zc3h14
Zinc finger CCCH domain-containing protein 14; Involved in poly(A) tail length control in neuronal cells. Binds the polyadenosine RNA oligonucleotides. Belongs to the ZC3H14 family.
   
  
 0.441
Eepd1
Endonuclease/exonuclease/phosphatase family domain-containing protein 1.
   
  
 0.439
Slc25a47
Solute carrier family 25 member 47; Uncoupling protein which may catalyze the physiological 'proton leak' in liver; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.438
Rtn1
Reticulon-1; May be involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells.
   
  
 0.426
Ddhd1
DDHD domain-containing 1.
      
 0.420
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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