node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cd44 | Cd48 | ENSRNOP00000009000 | ENSRNOP00000006306 | CD44 antigen. | CD48 antigen; Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation. | 0.631 |
Cd44 | Cytip | ENSRNOP00000009000 | ENSRNOP00000006387 | CD44 antigen. | Cytohesin-interacting protein; By its binding to cytohesin-1 (CYTH1), it modifies activation of ARFs by CYTH1 and its precise function may be to sequester CYTH1 in the cytoplasm. | 0.471 |
Cd44 | Il6 | ENSRNOP00000009000 | ENSRNOP00000013732 | CD44 antigen. | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] | 0.915 |
Cd44 | Il7r | ENSRNOP00000009000 | ENSRNOP00000070236 | CD44 antigen. | Interleukin 7 receptor (Predicted). | 0.753 |
Cd48 | Cd44 | ENSRNOP00000006306 | ENSRNOP00000009000 | CD48 antigen; Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation. | CD44 antigen. | 0.631 |
Cd48 | Cytip | ENSRNOP00000006306 | ENSRNOP00000006387 | CD48 antigen; Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation. | Cytohesin-interacting protein; By its binding to cytohesin-1 (CYTH1), it modifies activation of ARFs by CYTH1 and its precise function may be to sequester CYTH1 in the cytoplasm. | 0.577 |
Cd48 | Il7r | ENSRNOP00000006306 | ENSRNOP00000070236 | CD48 antigen; Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation. | Interleukin 7 receptor (Predicted). | 0.757 |
Cln8 | Cytip | ENSRNOP00000016756 | ENSRNOP00000006387 | Protein CLN8; Could play a role in cell proliferation during neuronal differentiation and in protection against cell death. | Cytohesin-interacting protein; By its binding to cytohesin-1 (CYTH1), it modifies activation of ARFs by CYTH1 and its precise function may be to sequester CYTH1 in the cytoplasm. | 0.511 |
Cyth1 | Cyth2 | ENSRNOP00000004196 | ENSRNOP00000028588 | Cytohesin-1; Promotes guanine-nucleotide exchange on ARF1, ARF5 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. Plays an important role in membrane trafficking, during junctional remodeling and epithelial polarization, through regulation of ARF6 activity. | Cytohesin-2; Acts as a guanine-nucleotide exchange factor (GEF). Promotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. The cell membrane form, in association with ARL4 proteins, recruits ARF6 to the plasma membrane (By similarity). Involved in neurite growth (By similarity). | 0.666 |
Cyth1 | Cyth3 | ENSRNOP00000004196 | ENSRNOP00000001412 | Cytohesin-1; Promotes guanine-nucleotide exchange on ARF1, ARF5 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. Plays an important role in membrane trafficking, during junctional remodeling and epithelial polarization, through regulation of ARF6 activity. | Cytohesin-3; Promotes guanine-nucleotide exchange on ARF1. Promotes the activation of ARF factors through replacement of GDP with GTP (By similarity). | 0.635 |
Cyth1 | Cytip | ENSRNOP00000004196 | ENSRNOP00000006387 | Cytohesin-1; Promotes guanine-nucleotide exchange on ARF1, ARF5 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. Plays an important role in membrane trafficking, during junctional remodeling and epithelial polarization, through regulation of ARF6 activity. | Cytohesin-interacting protein; By its binding to cytohesin-1 (CYTH1), it modifies activation of ARFs by CYTH1 and its precise function may be to sequester CYTH1 in the cytoplasm. | 0.890 |
Cyth2 | Cyth1 | ENSRNOP00000028588 | ENSRNOP00000004196 | Cytohesin-2; Acts as a guanine-nucleotide exchange factor (GEF). Promotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. The cell membrane form, in association with ARL4 proteins, recruits ARF6 to the plasma membrane (By similarity). Involved in neurite growth (By similarity). | Cytohesin-1; Promotes guanine-nucleotide exchange on ARF1, ARF5 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. Plays an important role in membrane trafficking, during junctional remodeling and epithelial polarization, through regulation of ARF6 activity. | 0.666 |
Cyth2 | Cyth3 | ENSRNOP00000028588 | ENSRNOP00000001412 | Cytohesin-2; Acts as a guanine-nucleotide exchange factor (GEF). Promotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. The cell membrane form, in association with ARL4 proteins, recruits ARF6 to the plasma membrane (By similarity). Involved in neurite growth (By similarity). | Cytohesin-3; Promotes guanine-nucleotide exchange on ARF1. Promotes the activation of ARF factors through replacement of GDP with GTP (By similarity). | 0.607 |
Cyth2 | Cytip | ENSRNOP00000028588 | ENSRNOP00000006387 | Cytohesin-2; Acts as a guanine-nucleotide exchange factor (GEF). Promotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. The cell membrane form, in association with ARL4 proteins, recruits ARF6 to the plasma membrane (By similarity). Involved in neurite growth (By similarity). | Cytohesin-interacting protein; By its binding to cytohesin-1 (CYTH1), it modifies activation of ARFs by CYTH1 and its precise function may be to sequester CYTH1 in the cytoplasm. | 0.472 |
Cyth3 | Cyth1 | ENSRNOP00000001412 | ENSRNOP00000004196 | Cytohesin-3; Promotes guanine-nucleotide exchange on ARF1. Promotes the activation of ARF factors through replacement of GDP with GTP (By similarity). | Cytohesin-1; Promotes guanine-nucleotide exchange on ARF1, ARF5 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. Plays an important role in membrane trafficking, during junctional remodeling and epithelial polarization, through regulation of ARF6 activity. | 0.635 |
Cyth3 | Cyth2 | ENSRNOP00000001412 | ENSRNOP00000028588 | Cytohesin-3; Promotes guanine-nucleotide exchange on ARF1. Promotes the activation of ARF factors through replacement of GDP with GTP (By similarity). | Cytohesin-2; Acts as a guanine-nucleotide exchange factor (GEF). Promotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. The cell membrane form, in association with ARL4 proteins, recruits ARF6 to the plasma membrane (By similarity). Involved in neurite growth (By similarity). | 0.607 |
Cyth3 | Cytip | ENSRNOP00000001412 | ENSRNOP00000006387 | Cytohesin-3; Promotes guanine-nucleotide exchange on ARF1. Promotes the activation of ARF factors through replacement of GDP with GTP (By similarity). | Cytohesin-interacting protein; By its binding to cytohesin-1 (CYTH1), it modifies activation of ARFs by CYTH1 and its precise function may be to sequester CYTH1 in the cytoplasm. | 0.627 |
Cytip | Cd44 | ENSRNOP00000006387 | ENSRNOP00000009000 | Cytohesin-interacting protein; By its binding to cytohesin-1 (CYTH1), it modifies activation of ARFs by CYTH1 and its precise function may be to sequester CYTH1 in the cytoplasm. | CD44 antigen. | 0.471 |
Cytip | Cd48 | ENSRNOP00000006387 | ENSRNOP00000006306 | Cytohesin-interacting protein; By its binding to cytohesin-1 (CYTH1), it modifies activation of ARFs by CYTH1 and its precise function may be to sequester CYTH1 in the cytoplasm. | CD48 antigen; Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation. | 0.577 |
Cytip | Cln8 | ENSRNOP00000006387 | ENSRNOP00000016756 | Cytohesin-interacting protein; By its binding to cytohesin-1 (CYTH1), it modifies activation of ARFs by CYTH1 and its precise function may be to sequester CYTH1 in the cytoplasm. | Protein CLN8; Could play a role in cell proliferation during neuronal differentiation and in protection against cell death. | 0.511 |