STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IghmImmunoglobulin heavy constant mu. (495 aa)    
Predicted Functional Partners:
Jchain
Immunoglobulin joining chain.
   
 0.958
Cd79b
B29/Ig-beta/CD79b.
   
 
 0.812
IGHG1_RAT
Ig gamma-1 chain C region.
  
0.793
Igll1
Immunoglobulin lambda-like polypeptide 1.
   
 0.793
Igh-1a
Ig gamma-2B chain C region.
  
0.786
Cd79a
Ig-like domain-containing protein.
   
 
 0.730
Vpreb3
Pre-B lymphocyte gene 3 (Predicted), isoform CRA_b.
   
 0.713
Cd5l
Cd5 molecule-like.
   
 
 0.695
Pigr
Polymeric immunoglobulin receptor; This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment.
   
 
 0.694
Cd22
CD22 antigen (Predicted).
   
 
 0.650
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.