| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cars | Slc1a4 | ENSRNOP00000050342 | ENSRNOP00000007002 | Cysteinyl-tRNA synthetase (Predicted), isoform CRA_b. | Solute carrier family 1 (Glutamate/neutral amino acid transporter), member 4. | 0.612 |
| Cars | Slc3a2 | ENSRNOP00000050342 | ENSRNOP00000025196 | Cysteinyl-tRNA synthetase (Predicted), isoform CRA_b. | 4F2 cell-surface antigen heavy chain; Component of several heterodimeric amino acid transporter complexes. The precise substrate specificity depends on the other subunit in the heterodimer. The heterodimer with SLC3A2 functions as sodium- independent, high-affinity transporter that mediates uptake of large neutral amino acids such as phenylalanine, tyrosine, L-DOPA, leucine, histidine, methionine and tryptophan. The complexes with SLC7A6 and SLC7A7 mediate uptake of dibasic amino acids (By similarity). The complexes function as amino acid exchangers. Required for targeting of SLC7A5 an [...] | 0.413 |
| Phgdh | Slc1a4 | ENSRNOP00000053019 | ENSRNOP00000007002 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Does not catalyze the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate and the reversible oxidation of (S)-malate to oxaloacetate. | Solute carrier family 1 (Glutamate/neutral amino acid transporter), member 4. | 0.616 |
| Phgdh | Slc7a5 | ENSRNOP00000053019 | ENSRNOP00000025784 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Does not catalyze the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate and the reversible oxidation of (S)-malate to oxaloacetate. | Large neutral amino acids transporter small subunit 1; The heterodimer with SLC3A2 functions as sodium-independent, high-affinity transporter that mediates uptake of large neutral amino acids such as phenylalanine, tyrosine, L-DOPA, leucine, histidine, methionine and tryptophan. Functions as an amino acid exchanger (By similarity). May play a role in the transport of L-DOPA across the blood-brain barrier (By similarity). May act as the major transporter of tyrosine in fibroblasts (By similarity). May mediate blood-to-retina L-leucine transport across the inner blood-retinal barrier (Pr [...] | 0.476 |
| Slc1a4 | Cars | ENSRNOP00000007002 | ENSRNOP00000050342 | Solute carrier family 1 (Glutamate/neutral amino acid transporter), member 4. | Cysteinyl-tRNA synthetase (Predicted), isoform CRA_b. | 0.612 |
| Slc1a4 | Phgdh | ENSRNOP00000007002 | ENSRNOP00000053019 | Solute carrier family 1 (Glutamate/neutral amino acid transporter), member 4. | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Does not catalyze the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate and the reversible oxidation of (S)-malate to oxaloacetate. | 0.616 |
| Slc1a4 | Slc38a2 | ENSRNOP00000007002 | ENSRNOP00000031532 | Solute carrier family 1 (Glutamate/neutral amino acid transporter), member 4. | Sodium-coupled neutral amino acid transporter 2; Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of neutral amino acids and sodium ions with a stoichiometry of 1:1. May function in the transport of amino acids at the blood-brain barrier and in the supply of maternal nutrients to the fetus through the placenta. | 0.623 |
| Slc1a4 | Slc3a2 | ENSRNOP00000007002 | ENSRNOP00000025196 | Solute carrier family 1 (Glutamate/neutral amino acid transporter), member 4. | 4F2 cell-surface antigen heavy chain; Component of several heterodimeric amino acid transporter complexes. The precise substrate specificity depends on the other subunit in the heterodimer. The heterodimer with SLC3A2 functions as sodium- independent, high-affinity transporter that mediates uptake of large neutral amino acids such as phenylalanine, tyrosine, L-DOPA, leucine, histidine, methionine and tryptophan. The complexes with SLC7A6 and SLC7A7 mediate uptake of dibasic amino acids (By similarity). The complexes function as amino acid exchangers. Required for targeting of SLC7A5 an [...] | 0.751 |
| Slc1a4 | Slc43a2 | ENSRNOP00000007002 | ENSRNOP00000005100 | Solute carrier family 1 (Glutamate/neutral amino acid transporter), member 4. | Solute carrier family 43, member 2 (Predicted), isoform CRA_a. | 0.630 |
| Slc1a4 | Slc6a14 | ENSRNOP00000007002 | ENSRNOP00000007967 | Solute carrier family 1 (Glutamate/neutral amino acid transporter), member 4. | Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. | 0.631 |
| Slc1a4 | Slc6a9 | ENSRNOP00000007002 | ENSRNOP00000070161 | Solute carrier family 1 (Glutamate/neutral amino acid transporter), member 4. | Sodium- and chloride-dependent glycine transporter 1; Terminates the action of glycine by its high affinity sodium- dependent reuptake into presynaptic terminals. May play a role in regulation of glycine levels in NMDA receptor-mediated neurotransmission; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A9 subfamily. | 0.616 |
| Slc1a4 | Slc7a1 | ENSRNOP00000007002 | ENSRNOP00000072647 | Solute carrier family 1 (Glutamate/neutral amino acid transporter), member 4. | High affinity cationic amino acid transporter 1; High-affinity, low capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) in non-hepatic tissues; Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family. | 0.705 |
| Slc1a4 | Slc7a10 | ENSRNOP00000007002 | ENSRNOP00000015205 | Solute carrier family 1 (Glutamate/neutral amino acid transporter), member 4. | Asc-type amino acid transporter 1; Sodium-independent, high affinity transport of small neutral D- and L-amino acids and amino acid-related compounds. May play a role in the modulation of glutamatergic transmission through mobilization of D-serine at the glutamatergic synapse (By similarity). | 0.680 |
| Slc1a4 | Slc7a5 | ENSRNOP00000007002 | ENSRNOP00000025784 | Solute carrier family 1 (Glutamate/neutral amino acid transporter), member 4. | Large neutral amino acids transporter small subunit 1; The heterodimer with SLC3A2 functions as sodium-independent, high-affinity transporter that mediates uptake of large neutral amino acids such as phenylalanine, tyrosine, L-DOPA, leucine, histidine, methionine and tryptophan. Functions as an amino acid exchanger (By similarity). May play a role in the transport of L-DOPA across the blood-brain barrier (By similarity). May act as the major transporter of tyrosine in fibroblasts (By similarity). May mediate blood-to-retina L-leucine transport across the inner blood-retinal barrier (Pr [...] | 0.735 |
| Slc38a2 | Slc1a4 | ENSRNOP00000031532 | ENSRNOP00000007002 | Sodium-coupled neutral amino acid transporter 2; Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of neutral amino acids and sodium ions with a stoichiometry of 1:1. May function in the transport of amino acids at the blood-brain barrier and in the supply of maternal nutrients to the fetus through the placenta. | Solute carrier family 1 (Glutamate/neutral amino acid transporter), member 4. | 0.623 |
| Slc38a2 | Slc3a2 | ENSRNOP00000031532 | ENSRNOP00000025196 | Sodium-coupled neutral amino acid transporter 2; Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of neutral amino acids and sodium ions with a stoichiometry of 1:1. May function in the transport of amino acids at the blood-brain barrier and in the supply of maternal nutrients to the fetus through the placenta. | 4F2 cell-surface antigen heavy chain; Component of several heterodimeric amino acid transporter complexes. The precise substrate specificity depends on the other subunit in the heterodimer. The heterodimer with SLC3A2 functions as sodium- independent, high-affinity transporter that mediates uptake of large neutral amino acids such as phenylalanine, tyrosine, L-DOPA, leucine, histidine, methionine and tryptophan. The complexes with SLC7A6 and SLC7A7 mediate uptake of dibasic amino acids (By similarity). The complexes function as amino acid exchangers. Required for targeting of SLC7A5 an [...] | 0.681 |
| Slc38a2 | Slc43a2 | ENSRNOP00000031532 | ENSRNOP00000005100 | Sodium-coupled neutral amino acid transporter 2; Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of neutral amino acids and sodium ions with a stoichiometry of 1:1. May function in the transport of amino acids at the blood-brain barrier and in the supply of maternal nutrients to the fetus through the placenta. | Solute carrier family 43, member 2 (Predicted), isoform CRA_a. | 0.585 |
| Slc38a2 | Slc6a14 | ENSRNOP00000031532 | ENSRNOP00000007967 | Sodium-coupled neutral amino acid transporter 2; Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of neutral amino acids and sodium ions with a stoichiometry of 1:1. May function in the transport of amino acids at the blood-brain barrier and in the supply of maternal nutrients to the fetus through the placenta. | Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. | 0.613 |
| Slc38a2 | Slc6a9 | ENSRNOP00000031532 | ENSRNOP00000070161 | Sodium-coupled neutral amino acid transporter 2; Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of neutral amino acids and sodium ions with a stoichiometry of 1:1. May function in the transport of amino acids at the blood-brain barrier and in the supply of maternal nutrients to the fetus through the placenta. | Sodium- and chloride-dependent glycine transporter 1; Terminates the action of glycine by its high affinity sodium- dependent reuptake into presynaptic terminals. May play a role in regulation of glycine levels in NMDA receptor-mediated neurotransmission; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A9 subfamily. | 0.410 |
| Slc38a2 | Slc7a1 | ENSRNOP00000031532 | ENSRNOP00000072647 | Sodium-coupled neutral amino acid transporter 2; Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of neutral amino acids and sodium ions with a stoichiometry of 1:1. May function in the transport of amino acids at the blood-brain barrier and in the supply of maternal nutrients to the fetus through the placenta. | High affinity cationic amino acid transporter 1; High-affinity, low capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) in non-hepatic tissues; Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family. | 0.654 |
