node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Anapc1 | Anapc11 | ENSRNOP00000052727 | ENSRNOP00000051837 | Anaphase promoting complex subunit 1 (Predicted). | Similar to anaphase promoting complex subunit 11 homolog (Predicted), isoform CRA_a. | 0.996 |
Anapc1 | Anapc16 | ENSRNOP00000052727 | ENSRNOP00000000702 | Anaphase promoting complex subunit 1 (Predicted). | Anaphase-promoting complex subunit 16. | 0.993 |
Anapc1 | Anapc2 | ENSRNOP00000052727 | ENSRNOP00000015099 | Anaphase promoting complex subunit 1 (Predicted). | Anaphase-promoting complex subunit 2; Belongs to the cullin family. | 0.996 |
Anapc1 | Anapc4 | ENSRNOP00000052727 | ENSRNOP00000006093 | Anaphase promoting complex subunit 1 (Predicted). | Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. | 0.998 |
Anapc1 | Anapc5 | ENSRNOP00000052727 | ENSRNOP00000001794 | Anaphase promoting complex subunit 1 (Predicted). | Anaphase-promoting complex subunit 5; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (By similarity). | 0.997 |
Anapc1 | Cdc16 | ENSRNOP00000052727 | ENSRNOP00000023736 | Anaphase promoting complex subunit 1 (Predicted). | CDC16 cell division cycle 16 homolog (S. cerevisiae). | 0.996 |
Anapc1 | Cdc20 | ENSRNOP00000052727 | ENSRNOP00000037772 | Anaphase promoting complex subunit 1 (Predicted). | Cell division cycle protein 20 homolog; Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentia [...] | 0.995 |
Anapc1 | Cdc23 | ENSRNOP00000052727 | ENSRNOP00000035675 | Anaphase promoting complex subunit 1 (Predicted). | CDC23 (Cell division cycle 23, yeast, homolog), isoform CRA_b. | 0.995 |
Anapc1 | Cdc27 | ENSRNOP00000052727 | ENSRNOP00000007963 | Anaphase promoting complex subunit 1 (Predicted). | Cell division cycle protein 27 homolog; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (By similarity). | 0.997 |
Anapc1 | Fzr1 | ENSRNOP00000052727 | ENSRNOP00000005624 | Anaphase promoting complex subunit 1 (Predicted). | Fizzy/cell division cycle 20 related 1 (Drosophila) (Predicted), isoform CRA_a. | 0.977 |
Anapc11 | Anapc1 | ENSRNOP00000051837 | ENSRNOP00000052727 | Similar to anaphase promoting complex subunit 11 homolog (Predicted), isoform CRA_a. | Anaphase promoting complex subunit 1 (Predicted). | 0.996 |
Anapc11 | Anapc16 | ENSRNOP00000051837 | ENSRNOP00000000702 | Similar to anaphase promoting complex subunit 11 homolog (Predicted), isoform CRA_a. | Anaphase-promoting complex subunit 16. | 0.966 |
Anapc11 | Anapc2 | ENSRNOP00000051837 | ENSRNOP00000015099 | Similar to anaphase promoting complex subunit 11 homolog (Predicted), isoform CRA_a. | Anaphase-promoting complex subunit 2; Belongs to the cullin family. | 0.997 |
Anapc11 | Anapc4 | ENSRNOP00000051837 | ENSRNOP00000006093 | Similar to anaphase promoting complex subunit 11 homolog (Predicted), isoform CRA_a. | Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. | 0.997 |
Anapc11 | Anapc5 | ENSRNOP00000051837 | ENSRNOP00000001794 | Similar to anaphase promoting complex subunit 11 homolog (Predicted), isoform CRA_a. | Anaphase-promoting complex subunit 5; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (By similarity). | 0.998 |
Anapc11 | Cdc16 | ENSRNOP00000051837 | ENSRNOP00000023736 | Similar to anaphase promoting complex subunit 11 homolog (Predicted), isoform CRA_a. | CDC16 cell division cycle 16 homolog (S. cerevisiae). | 0.996 |
Anapc11 | Cdc20 | ENSRNOP00000051837 | ENSRNOP00000037772 | Similar to anaphase promoting complex subunit 11 homolog (Predicted), isoform CRA_a. | Cell division cycle protein 20 homolog; Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentia [...] | 0.986 |
Anapc11 | Cdc23 | ENSRNOP00000051837 | ENSRNOP00000035675 | Similar to anaphase promoting complex subunit 11 homolog (Predicted), isoform CRA_a. | CDC23 (Cell division cycle 23, yeast, homolog), isoform CRA_b. | 0.997 |
Anapc11 | Cdc27 | ENSRNOP00000051837 | ENSRNOP00000007963 | Similar to anaphase promoting complex subunit 11 homolog (Predicted), isoform CRA_a. | Cell division cycle protein 27 homolog; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (By similarity). | 0.997 |
Anapc11 | Fzr1 | ENSRNOP00000051837 | ENSRNOP00000005624 | Similar to anaphase promoting complex subunit 11 homolog (Predicted), isoform CRA_a. | Fizzy/cell division cycle 20 related 1 (Drosophila) (Predicted), isoform CRA_a. | 0.958 |