| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Il17a | Il22 | ENSRNOP00000016664 | ENSRNOP00000009776 | Interleukin-17A; Ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines. | Similar to TIF alpha protein (Predicted). | 0.923 |
| Il17a | Reg3b | ENSRNOP00000016664 | ENSRNOP00000008212 | Interleukin-17A; Ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines. | Regenerating islet-derived protein 3-beta 16.5 kDa form; Bactericidal C-type lectin which acts against several intestinal Gram-positive bacteria and Gram-negative bacteria. Lacks antibacterial activity against S.typhimurium. May play a role in protection against infection with S.enteritidis by inhibiting its translocation from the gut lumen into intestinal tissues and further extraintestinal tissues (By similarity). | 0.506 |
| Il17a | Reg3g | ENSRNOP00000016664 | ENSRNOP00000008665 | Interleukin-17A; Ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines. | Regenerating islet-derived protein 3-gamma 16.5 kDa form; Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. The uncleaved form has bacteriostatic activity, whereas the cleaved form has bactericidal activity against L.monocytogenes and methicillin-resistant S.aureus. Regulates keratinocyte proliferation and [...] | 0.592 |
| Il22 | Il17a | ENSRNOP00000009776 | ENSRNOP00000016664 | Similar to TIF alpha protein (Predicted). | Interleukin-17A; Ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines. | 0.923 |
| Il22 | Reg3a | ENSRNOP00000009776 | ENSRNOP00000008468 | Similar to TIF alpha protein (Predicted). | Regenerating islet-derived protein 3-alpha 16.5 kDa form; Bactericidal C-type lectin. Regulates keratinocyte proliferation and differentiation after skin injury via activation of EXTL3-PI3K-AKT signaling pathway (By similarity). | 0.630 |
| Il22 | Reg3b | ENSRNOP00000009776 | ENSRNOP00000008212 | Similar to TIF alpha protein (Predicted). | Regenerating islet-derived protein 3-beta 16.5 kDa form; Bactericidal C-type lectin which acts against several intestinal Gram-positive bacteria and Gram-negative bacteria. Lacks antibacterial activity against S.typhimurium. May play a role in protection against infection with S.enteritidis by inhibiting its translocation from the gut lumen into intestinal tissues and further extraintestinal tissues (By similarity). | 0.679 |
| Il22 | Reg3g | ENSRNOP00000009776 | ENSRNOP00000008665 | Similar to TIF alpha protein (Predicted). | Regenerating islet-derived protein 3-gamma 16.5 kDa form; Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. The uncleaved form has bacteriostatic activity, whereas the cleaved form has bactericidal activity against L.monocytogenes and methicillin-resistant S.aureus. Regulates keratinocyte proliferation and [...] | 0.752 |
| Itln1 | Reg3a | ENSRNOP00000006196 | ENSRNOP00000008468 | Intelectin 1. | Regenerating islet-derived protein 3-alpha 16.5 kDa form; Bactericidal C-type lectin. Regulates keratinocyte proliferation and differentiation after skin injury via activation of EXTL3-PI3K-AKT signaling pathway (By similarity). | 0.445 |
| Itln1 | Reg3b | ENSRNOP00000006196 | ENSRNOP00000008212 | Intelectin 1. | Regenerating islet-derived protein 3-beta 16.5 kDa form; Bactericidal C-type lectin which acts against several intestinal Gram-positive bacteria and Gram-negative bacteria. Lacks antibacterial activity against S.typhimurium. May play a role in protection against infection with S.enteritidis by inhibiting its translocation from the gut lumen into intestinal tissues and further extraintestinal tissues (By similarity). | 0.583 |
| Itln1 | Reg3g | ENSRNOP00000006196 | ENSRNOP00000008665 | Intelectin 1. | Regenerating islet-derived protein 3-gamma 16.5 kDa form; Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. The uncleaved form has bacteriostatic activity, whereas the cleaved form has bactericidal activity against L.monocytogenes and methicillin-resistant S.aureus. Regulates keratinocyte proliferation and [...] | 0.635 |
| LOC683849 | Prss1 | ENSRNOP00000043620 | ENSRNOP00000043068 | Similar to Anionic trypsin II precursor (Pretrypsinogen II); Belongs to the peptidase S1 family. | Anionic trypsin-1; Belongs to the peptidase S1 family. | 0.427 |
| LOC683849 | Prss2 | ENSRNOP00000043620 | ENSRNOP00000018853 | Similar to Anionic trypsin II precursor (Pretrypsinogen II); Belongs to the peptidase S1 family. | Anionic trypsin-2; Belongs to the peptidase S1 family. | 0.941 |
| LOC683849 | Reg3a | ENSRNOP00000043620 | ENSRNOP00000008468 | Similar to Anionic trypsin II precursor (Pretrypsinogen II); Belongs to the peptidase S1 family. | Regenerating islet-derived protein 3-alpha 16.5 kDa form; Bactericidal C-type lectin. Regulates keratinocyte proliferation and differentiation after skin injury via activation of EXTL3-PI3K-AKT signaling pathway (By similarity). | 0.483 |
| LOC683849 | Reg3b | ENSRNOP00000043620 | ENSRNOP00000008212 | Similar to Anionic trypsin II precursor (Pretrypsinogen II); Belongs to the peptidase S1 family. | Regenerating islet-derived protein 3-beta 16.5 kDa form; Bactericidal C-type lectin which acts against several intestinal Gram-positive bacteria and Gram-negative bacteria. Lacks antibacterial activity against S.typhimurium. May play a role in protection against infection with S.enteritidis by inhibiting its translocation from the gut lumen into intestinal tissues and further extraintestinal tissues (By similarity). | 0.484 |
| LOC683849 | Reg3g | ENSRNOP00000043620 | ENSRNOP00000008665 | Similar to Anionic trypsin II precursor (Pretrypsinogen II); Belongs to the peptidase S1 family. | Regenerating islet-derived protein 3-gamma 16.5 kDa form; Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. The uncleaved form has bacteriostatic activity, whereas the cleaved form has bactericidal activity against L.monocytogenes and methicillin-resistant S.aureus. Regulates keratinocyte proliferation and [...] | 0.460 |
| LOC683849 | Try5 | ENSRNOP00000043620 | ENSRNOP00000035514 | Similar to Anionic trypsin II precursor (Pretrypsinogen II); Belongs to the peptidase S1 family. | Trypsin 5; Belongs to the peptidase S1 family. | 0.405 |
| Lypd8 | Reg3a | ENSRNOP00000034245 | ENSRNOP00000008468 | LY6/PLAUR domain-containing 8. | Regenerating islet-derived protein 3-alpha 16.5 kDa form; Bactericidal C-type lectin. Regulates keratinocyte proliferation and differentiation after skin injury via activation of EXTL3-PI3K-AKT signaling pathway (By similarity). | 0.445 |
| Lypd8 | Reg3b | ENSRNOP00000034245 | ENSRNOP00000008212 | LY6/PLAUR domain-containing 8. | Regenerating islet-derived protein 3-beta 16.5 kDa form; Bactericidal C-type lectin which acts against several intestinal Gram-positive bacteria and Gram-negative bacteria. Lacks antibacterial activity against S.typhimurium. May play a role in protection against infection with S.enteritidis by inhibiting its translocation from the gut lumen into intestinal tissues and further extraintestinal tissues (By similarity). | 0.488 |
| Lypd8 | Reg3g | ENSRNOP00000034245 | ENSRNOP00000008665 | LY6/PLAUR domain-containing 8. | Regenerating islet-derived protein 3-gamma 16.5 kDa form; Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. The uncleaved form has bacteriostatic activity, whereas the cleaved form has bactericidal activity against L.monocytogenes and methicillin-resistant S.aureus. Regulates keratinocyte proliferation and [...] | 0.607 |
| Prss1 | LOC683849 | ENSRNOP00000043068 | ENSRNOP00000043620 | Anionic trypsin-1; Belongs to the peptidase S1 family. | Similar to Anionic trypsin II precursor (Pretrypsinogen II); Belongs to the peptidase S1 family. | 0.427 |
