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Prepl protein (Rattus norvegicus) - STRING interaction network
"Prepl" - Prolyl endopeptidase-like in Rattus norvegicus
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PreplProlyl endopeptidase-like; Probable serine peptidase whose precise substrate specificity remains unclear. Does not cleave peptides after a arginine or lysine residue. May play a role in the regulation of synaptic vesiscle exocytosis (726 aa)    
Predicted Functional Partners:
Slc3a1
Neutral and basic amino acid transport protein rBAT; Involved in the high-affinity sodium-independent transport of cystine and neutral and dibasic amino acids (system B(0,+)-like activity). May function as an activator of SLC7A9 and be involved in the high-affinity reabsorption of cystine in the kidney proximal tubule (683 aa)
   
   
  0.863
Plekhj1
Pleckstrin homology domain containing, family J member 1 (162 aa)
           
  0.801
Ppm1b
Protein phosphatase 1B; Enzyme with a broad specificity. Dephosphorylates PRKAA1 and PRKAA2. Inhibits TBK1-mediated antiviral signaling by dephosphorylating it at ’Ser-172’. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB (By similarity); Belongs to the PP2C family (396 aa)
     
   
  0.790
Sars2
seryl-tRNA synthetase 2, mitochondrial (518 aa)
         
  0.778
Spire2
Spire-type actin nucleation factor 2 (714 aa)
     
   
  0.773
Dpp9
Dipeptidyl peptidase 9 (862 aa)
   
 
  0.769
Dpp8
Dipeptidylpeptidase 8 (Predicted), isoform CRA_a; Dipeptidylpeptidase 8 (651 aa)
   
 
  0.768
Abhd13
Similar to 1110065L07Rik protein (Predicted), isoform CRA_b; Abhydrolase domain containing 13 (337 aa)
           
  0.752
Surf2
Surfeit locus protein 2-like (253 aa)
           
  0.713
ENSRNOG00000005167
Surfeit 2 (253 aa)
           
  0.713
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Gunn rats, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus norvegicus, Rattus rattiscus, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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