STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PpigPeptidyl-prolyl cis-trans isomerase G; PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. May be implicated in the folding, transport, and assembly of proteins. May play an important role in the regulation of pre-mRNA splicing. (752 aa)    
Predicted Functional Partners:
Ppwd1
Peptidylprolyl isomerase domain and WD repeat containing 1 (Predicted).
   
0.924
Cwc25
CWC25 spliceosome-associated protein homolog.
   
 0.920
Syf2
Pre-mRNA-splicing factor SYF2; Involved in pre-mRNA splicing as component of the spliceosome.
   
 0.911
Cdc40
Cell division cycle 40.
   
 0.910
Dhx38
DEAH-box helicase 38.
   
 0.906
Ppil1
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
  
 
0.906
Yju2
Coiled-coil domain containing 94.
   
 0.901
Srrm1
Serine and arginine repetitive matrix 1.
   
 0.885
Srrm2
Serine/arginine repetitive matrix 2.
   
 0.877
Cwc22
CWC22 spliceosome-associated protein homolog.
   
 0.873
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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