| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Clec2d | Klrb1c | ENSRNOP00000010098 | ENSRNOP00000010312 | C-type lectin domain family 2 member D5; Lectin-type cell surface receptor. | Killer cell lectin-like receptor subfamily B member 1F; Binds CLEC2I/Clr-g leading to activation of natural killer cells or stimulation of IL-2 production and proliferation of T-cells in response to antigen stimulation. May contribute to the formation of the immunological synapse between T-cells and antigen-presenting dendritic cells (By similarity). | 0.509 |
| Klra22 | Klrb1c | ENSRNOP00000070244 | ENSRNOP00000010312 | Killer cell lectin-like receptor subfamily A, member 22. | Killer cell lectin-like receptor subfamily B member 1F; Binds CLEC2I/Clr-g leading to activation of natural killer cells or stimulation of IL-2 production and proliferation of T-cells in response to antigen stimulation. May contribute to the formation of the immunological synapse between T-cells and antigen-presenting dendritic cells (By similarity). | 0.651 |
| Klra22 | Klrk1 | ENSRNOP00000070244 | ENSRNOP00000071035 | Killer cell lectin-like receptor subfamily A, member 22. | NKG2-D type II integral membrane protein; Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress- inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-exp [...] | 0.732 |
| Klra22 | Ncr1 | ENSRNOP00000070244 | ENSRNOP00000025080 | Killer cell lectin-like receptor subfamily A, member 22. | Natural cytotoxicity triggering receptor 1; Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. | 0.693 |
| Klrb1c | Clec2d | ENSRNOP00000010312 | ENSRNOP00000010098 | Killer cell lectin-like receptor subfamily B member 1F; Binds CLEC2I/Clr-g leading to activation of natural killer cells or stimulation of IL-2 production and proliferation of T-cells in response to antigen stimulation. May contribute to the formation of the immunological synapse between T-cells and antigen-presenting dendritic cells (By similarity). | C-type lectin domain family 2 member D5; Lectin-type cell surface receptor. | 0.509 |
| Klrb1c | Klra22 | ENSRNOP00000010312 | ENSRNOP00000070244 | Killer cell lectin-like receptor subfamily B member 1F; Binds CLEC2I/Clr-g leading to activation of natural killer cells or stimulation of IL-2 production and proliferation of T-cells in response to antigen stimulation. May contribute to the formation of the immunological synapse between T-cells and antigen-presenting dendritic cells (By similarity). | Killer cell lectin-like receptor subfamily A, member 22. | 0.651 |
| Klrb1c | Klrh1 | ENSRNOP00000010312 | ENSRNOP00000072464 | Killer cell lectin-like receptor subfamily B member 1F; Binds CLEC2I/Clr-g leading to activation of natural killer cells or stimulation of IL-2 production and proliferation of T-cells in response to antigen stimulation. May contribute to the formation of the immunological synapse between T-cells and antigen-presenting dendritic cells (By similarity). | Killer cell lectin-like receptor subfamily H, member 1. | 0.528 |
| Klrb1c | Klrk1 | ENSRNOP00000010312 | ENSRNOP00000071035 | Killer cell lectin-like receptor subfamily B member 1F; Binds CLEC2I/Clr-g leading to activation of natural killer cells or stimulation of IL-2 production and proliferation of T-cells in response to antigen stimulation. May contribute to the formation of the immunological synapse between T-cells and antigen-presenting dendritic cells (By similarity). | NKG2-D type II integral membrane protein; Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress- inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-exp [...] | 0.780 |
| Klrb1c | Ly49i2 | ENSRNOP00000010312 | ENSRNOP00000072569 | Killer cell lectin-like receptor subfamily B member 1F; Binds CLEC2I/Clr-g leading to activation of natural killer cells or stimulation of IL-2 production and proliferation of T-cells in response to antigen stimulation. May contribute to the formation of the immunological synapse between T-cells and antigen-presenting dendritic cells (By similarity). | Ly49 inhibitory receptor 2. | 0.604 |
| Klrb1c | Ncr1 | ENSRNOP00000010312 | ENSRNOP00000025080 | Killer cell lectin-like receptor subfamily B member 1F; Binds CLEC2I/Clr-g leading to activation of natural killer cells or stimulation of IL-2 production and proliferation of T-cells in response to antigen stimulation. May contribute to the formation of the immunological synapse between T-cells and antigen-presenting dendritic cells (By similarity). | Natural cytotoxicity triggering receptor 1; Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. | 0.623 |
| Klrb1c | Reep6 | ENSRNOP00000010312 | ENSRNOP00000039493 | Killer cell lectin-like receptor subfamily B member 1F; Binds CLEC2I/Clr-g leading to activation of natural killer cells or stimulation of IL-2 production and proliferation of T-cells in response to antigen stimulation. May contribute to the formation of the immunological synapse between T-cells and antigen-presenting dendritic cells (By similarity). | Receptor expression-enhancing protein 6; Required for correct function and survival of retinal photoreceptors (By similarity). Required for retinal development (By similarity). In rod photoreceptors, facilitates stability and/or trafficking of guanylate cyclases and is required to maintain endoplasmic reticulum and mitochondrial homeostasis (By similarity). May play a role in clathrin-coated intracellular vesicle trafficking of proteins from the endoplasmic reticulum to the retinal rod plasma membrane (By similarity); Belongs to the DP1 family. | 0.505 |
| Klrb1c | Stx18 | ENSRNOP00000010312 | ENSRNOP00000008410 | Killer cell lectin-like receptor subfamily B member 1F; Binds CLEC2I/Clr-g leading to activation of natural killer cells or stimulation of IL-2 production and proliferation of T-cells in response to antigen stimulation. May contribute to the formation of the immunological synapse between T-cells and antigen-presenting dendritic cells (By similarity). | Syntaxin-18; Syntaxin that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER. | 0.512 |
| Klrb1c | Stx8 | ENSRNOP00000010312 | ENSRNOP00000005204 | Killer cell lectin-like receptor subfamily B member 1F; Binds CLEC2I/Clr-g leading to activation of natural killer cells or stimulation of IL-2 production and proliferation of T-cells in response to antigen stimulation. May contribute to the formation of the immunological synapse between T-cells and antigen-presenting dendritic cells (By similarity). | Syntaxin-8; Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis- Golgi membranes to the ER. | 0.494 |
| Klrb1c | Vti1a | ENSRNOP00000010312 | ENSRNOP00000058953 | Killer cell lectin-like receptor subfamily B member 1F; Binds CLEC2I/Clr-g leading to activation of natural killer cells or stimulation of IL-2 production and proliferation of T-cells in response to antigen stimulation. May contribute to the formation of the immunological synapse between T-cells and antigen-presenting dendritic cells (By similarity). | Vesicle transport through interaction with t-SNAREs homolog 1A; V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. Involved in vesicular transport from the late endosomes to the trans-Golgi network. Along with VAMP7, involved in an non-conventional RAB1-dependent traffic route to the cell surface used by KCNIP1 and KCND2 (By similarity). May be concerned with increased secretion of cytokines as [...] | 0.505 |
| Klrh1 | Klrb1c | ENSRNOP00000072464 | ENSRNOP00000010312 | Killer cell lectin-like receptor subfamily H, member 1. | Killer cell lectin-like receptor subfamily B member 1F; Binds CLEC2I/Clr-g leading to activation of natural killer cells or stimulation of IL-2 production and proliferation of T-cells in response to antigen stimulation. May contribute to the formation of the immunological synapse between T-cells and antigen-presenting dendritic cells (By similarity). | 0.528 |
| Klrk1 | Klra22 | ENSRNOP00000071035 | ENSRNOP00000070244 | NKG2-D type II integral membrane protein; Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress- inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-exp [...] | Killer cell lectin-like receptor subfamily A, member 22. | 0.732 |
| Klrk1 | Klrb1c | ENSRNOP00000071035 | ENSRNOP00000010312 | NKG2-D type II integral membrane protein; Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress- inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-exp [...] | Killer cell lectin-like receptor subfamily B member 1F; Binds CLEC2I/Clr-g leading to activation of natural killer cells or stimulation of IL-2 production and proliferation of T-cells in response to antigen stimulation. May contribute to the formation of the immunological synapse between T-cells and antigen-presenting dendritic cells (By similarity). | 0.780 |
| Klrk1 | Ncr1 | ENSRNOP00000071035 | ENSRNOP00000025080 | NKG2-D type II integral membrane protein; Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress- inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-exp [...] | Natural cytotoxicity triggering receptor 1; Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. | 0.894 |
| Ly49i2 | Klrb1c | ENSRNOP00000072569 | ENSRNOP00000010312 | Ly49 inhibitory receptor 2. | Killer cell lectin-like receptor subfamily B member 1F; Binds CLEC2I/Clr-g leading to activation of natural killer cells or stimulation of IL-2 production and proliferation of T-cells in response to antigen stimulation. May contribute to the formation of the immunological synapse between T-cells and antigen-presenting dendritic cells (By similarity). | 0.604 |
| Ly49i2 | Ncr1 | ENSRNOP00000072569 | ENSRNOP00000025080 | Ly49 inhibitory receptor 2. | Natural cytotoxicity triggering receptor 1; Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. | 0.439 |
