node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cmpk1 | Cmpk2 | ENSRNOP00000068780 | ENSRNOP00000043468 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Cytidine/uridine monophosphate kinase 2. | 0.973 |
Cmpk1 | Dck | ENSRNOP00000068780 | ENSRNOP00000004440 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Deoxycytidine kinase; Required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG) and deoxyadenosine (dA). | 0.957 |
Cmpk1 | Nme1 | ENSRNOP00000068780 | ENSRNOP00000003658 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Nucleoside diphosphate kinase A; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for n [...] | 0.949 |
Cmpk1 | Nme2 | ENSRNOP00000068780 | ENSRNOP00000003611 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Nucleoside diphosphate kinase B; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity). Negatively regulates Rho activity by interacting with AKAP13/LBC. Acts as a transcriptional activator of the MYC gene; binds DNA non-specifically. Binds to both single-stranded guanine- and cytosine-rich strands within the nuclease hypersensitive element (NHE) III(1) region of the MYC gene promoter. Does not bind to duplex NHE I [...] | 0.948 |
Cmpk1 | Nme4 | ENSRNOP00000068780 | ENSRNOP00000068775 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Peroxisomal 2,4-dienoyl-CoA reductase. | 0.948 |
Cmpk1 | Rrm1 | ENSRNOP00000068780 | ENSRNOP00000064166 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.961 |
Cmpk1 | Uck1 | ENSRNOP00000068780 | ENSRNOP00000015792 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Uridine-cytidine kinase; Belongs to the uridine kinase family. | 0.964 |
Cmpk1 | Uckl1 | ENSRNOP00000068780 | ENSRNOP00000020695 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Uridine-cytidine kinase; Belongs to the uridine kinase family. | 0.954 |
Cmpk1 | Umps | ENSRNOP00000068780 | ENSRNOP00000002450 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Uridine monophosphate synthetase, isoform CRA_a. | 0.965 |
Cmpk1 | Uprt | ENSRNOP00000068780 | ENSRNOP00000038431 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Uracil phosphoribosyltransferase homolog. | 0.954 |
Cmpk2 | Cmpk1 | ENSRNOP00000043468 | ENSRNOP00000068780 | Cytidine/uridine monophosphate kinase 2. | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | 0.973 |
Cmpk2 | Dck | ENSRNOP00000043468 | ENSRNOP00000004440 | Cytidine/uridine monophosphate kinase 2. | Deoxycytidine kinase; Required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG) and deoxyadenosine (dA). | 0.950 |
Cmpk2 | Nme1 | ENSRNOP00000043468 | ENSRNOP00000003658 | Cytidine/uridine monophosphate kinase 2. | Nucleoside diphosphate kinase A; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for n [...] | 0.942 |
Cmpk2 | Nme2 | ENSRNOP00000043468 | ENSRNOP00000003611 | Cytidine/uridine monophosphate kinase 2. | Nucleoside diphosphate kinase B; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity). Negatively regulates Rho activity by interacting with AKAP13/LBC. Acts as a transcriptional activator of the MYC gene; binds DNA non-specifically. Binds to both single-stranded guanine- and cytosine-rich strands within the nuclease hypersensitive element (NHE) III(1) region of the MYC gene promoter. Does not bind to duplex NHE I [...] | 0.942 |
Cmpk2 | Nme4 | ENSRNOP00000043468 | ENSRNOP00000068775 | Cytidine/uridine monophosphate kinase 2. | Peroxisomal 2,4-dienoyl-CoA reductase. | 0.900 |
Cmpk2 | Rrm1 | ENSRNOP00000043468 | ENSRNOP00000064166 | Cytidine/uridine monophosphate kinase 2. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.964 |
Cmpk2 | Uck1 | ENSRNOP00000043468 | ENSRNOP00000015792 | Cytidine/uridine monophosphate kinase 2. | Uridine-cytidine kinase; Belongs to the uridine kinase family. | 0.920 |
Cmpk2 | Uckl1 | ENSRNOP00000043468 | ENSRNOP00000020695 | Cytidine/uridine monophosphate kinase 2. | Uridine-cytidine kinase; Belongs to the uridine kinase family. | 0.918 |
Cmpk2 | Umps | ENSRNOP00000043468 | ENSRNOP00000002450 | Cytidine/uridine monophosphate kinase 2. | Uridine monophosphate synthetase, isoform CRA_a. | 0.944 |
Cmpk2 | Uprt | ENSRNOP00000043468 | ENSRNOP00000038431 | Cytidine/uridine monophosphate kinase 2. | Uracil phosphoribosyltransferase homolog. | 0.946 |