Bub1b protein (Rattus norvegicus) - STRING interaction network

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Your Current Organism:

Rattus norvegicus

NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Bub1	Bub1b	ENSRNOP00000042114	ENSRNOP00000010406	Budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Predicted).	BUB1 mitotic checkpoint serine/threonine kinase B.	0.999
Bub1	Bub3	ENSRNOP00000042114	ENSRNOP00000028020	Budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Predicted).	BUB3 mitotic checkpoint protein.	0.998
Bub1	Cdc20	ENSRNOP00000042114	ENSRNOP00000037772	Budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Predicted).	Cell division cycle protein 20 homolog; Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentia [...]	0.999
Bub1	Cenpe	ENSRNOP00000042114	ENSRNOP00000032795	Budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Predicted).	Centromere protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.999
Bub1	Cenpf	ENSRNOP00000042114	ENSRNOP00000004525	Budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Predicted).	Centromere protein F.	0.998
Bub1	Mad2l1	ENSRNOP00000042114	ENSRNOP00000007285	Budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Predicted).	MAD2 (Mitotic arrest deficient, homolog)-like 1 (Yeast) (Predicted), isoform CRA_a.	0.999
Bub1	Ndc80	ENSRNOP00000042114	ENSRNOP00000072111	Budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Predicted).	NDC80 kinetochore complex component.	0.999
Bub1	Nuf2	ENSRNOP00000042114	ENSRNOP00000003650	Budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Predicted).	Kinetochore protein Nuf2; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules. Belongs to the NUF2 family.	0.999
Bub1	Plk1	ENSRNOP00000042114	ENSRNOP00000025629	Budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Predicted).	Serine/threonine-protein kinase PLK1; Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of anaphase- promoting complex/cyclosome (APC/C) inhibitors, and the regulation of mitotic exit and cytokinesis. Polo-like kinase proteins acts by binding and phosphorylating proteins are that already phosphorylated on a specific motif recognized by the POLO box domains. Phosphorylates BORA, BUB1B/BUBR1, C [...]	0.997
Bub1	Zwint	ENSRNOP00000042114	ENSRNOP00000067414	Budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Predicted).	ZW10 interactor; Part of the MIS12 complex, which is required for kinetochore formation and spindle checkpoint activity. Required to target ZW10 to the kinetochore at prometaphase (By similarity).	0.995
Bub1b	Bub1	ENSRNOP00000010406	ENSRNOP00000042114	BUB1 mitotic checkpoint serine/threonine kinase B.	Budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Predicted).	0.999
Bub1b	Bub3	ENSRNOP00000010406	ENSRNOP00000028020	BUB1 mitotic checkpoint serine/threonine kinase B.	BUB3 mitotic checkpoint protein.	0.999
Bub1b	Cdc20	ENSRNOP00000010406	ENSRNOP00000037772	BUB1 mitotic checkpoint serine/threonine kinase B.	Cell division cycle protein 20 homolog; Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentia [...]	0.999
Bub1b	Cenpe	ENSRNOP00000010406	ENSRNOP00000032795	BUB1 mitotic checkpoint serine/threonine kinase B.	Centromere protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.999
Bub1b	Cenpf	ENSRNOP00000010406	ENSRNOP00000004525	BUB1 mitotic checkpoint serine/threonine kinase B.	Centromere protein F.	0.998
Bub1b	Mad2l1	ENSRNOP00000010406	ENSRNOP00000007285	BUB1 mitotic checkpoint serine/threonine kinase B.	MAD2 (Mitotic arrest deficient, homolog)-like 1 (Yeast) (Predicted), isoform CRA_a.	0.999
Bub1b	Ndc80	ENSRNOP00000010406	ENSRNOP00000072111	BUB1 mitotic checkpoint serine/threonine kinase B.	NDC80 kinetochore complex component.	0.998
Bub1b	Nuf2	ENSRNOP00000010406	ENSRNOP00000003650	BUB1 mitotic checkpoint serine/threonine kinase B.	Kinetochore protein Nuf2; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules. Belongs to the NUF2 family.	0.998
Bub1b	Plk1	ENSRNOP00000010406	ENSRNOP00000025629	BUB1 mitotic checkpoint serine/threonine kinase B.	Serine/threonine-protein kinase PLK1; Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of anaphase- promoting complex/cyclosome (APC/C) inhibitors, and the regulation of mitotic exit and cytokinesis. Polo-like kinase proteins acts by binding and phosphorylating proteins are that already phosphorylated on a specific motif recognized by the POLO box domains. Phosphorylates BORA, BUB1B/BUBR1, C [...]	0.999
Bub1b	Zwint	ENSRNOP00000010406	ENSRNOP00000067414	BUB1 mitotic checkpoint serine/threonine kinase B.	ZW10 interactor; Part of the MIS12 complex, which is required for kinetochore formation and spindle checkpoint activity. Required to target ZW10 to the kinetochore at prometaphase (By similarity).	0.998

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