STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cgref1Cell growth regulator with EF hand domain protein 1; Mediates cell-cell adhesion in a calcium-dependent manner. Able to inhibit growth in several cell lines. (326 aa)    
Predicted Functional Partners:
Cgrrf1
Cell growth regulator with RING finger domain protein 1; Able to inhibit growth in several cell lines.
   
  
 0.687
Ckap2
Cytoskeleton-associated protein 2.
  
   
 0.534
Zyg11b
Zyg-11 family member B, cell cycle regulator.
      
 0.510
S100g
Protein S100-G.
   
  
 0.502
Tceanc
Transcription elongation factor A N-terminal and central domain-containing.
      
 0.499
Tmem130
Transmembrane protein 130.
   
  
 0.485
Serpina1f
Serine (or cysteine) peptidase inhibitor, clade A, member 1F; Belongs to the serpin family.
      
 0.465
Defb29
Beta-defensin 29; Has antibacterial activity; Belongs to the beta-defensin family.
      
 0.439
B3galt2
Hexosyltransferase.
      
 0.437
Trmo
tRNA (adenine(37)-N6)-methyltransferase; S-adenosyl-L-methionine-dependent methyltransferase responsible for the addition of the methyl group in the formation of N6-methyl-N6-threonylcarbamoyladenosine at position 37 (m(6)t(6)A37) of the tRNA anticodon loop of tRNA(Ser)(GCU). The methyl group of m(6)t(6)A37 may improve the efficiency of the tRNA decoding ability. May bind to tRNA.
      
 0.437
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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