| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Amotl2 | Ky | ENSRNOP00000075540 | ENSRNOP00000010992 | Angiomotin-like protein 2; Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments. Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. Participates in angiogenesis. May play a role in the polarity, proliferation and migration of endothelial cells. Selectively promotes FGF-induced MAPK activation through SRC (By similarity); Belongs to the angiomotin family. | Kyphoscoliosis (Predicted). | 0.581 |
| Amotl2 | Rab6b | ENSRNOP00000075540 | ENSRNOP00000068600 | Angiomotin-like protein 2; Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments. Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. Participates in angiogenesis. May play a role in the polarity, proliferation and migration of endothelial cells. Selectively promotes FGF-induced MAPK activation through SRC (By similarity); Belongs to the angiomotin family. | RAB6B, member RAS oncogene family. | 0.551 |
| Amotl2 | Ryk | ENSRNOP00000075540 | ENSRNOP00000063141 | Angiomotin-like protein 2; Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments. Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. Participates in angiogenesis. May play a role in the polarity, proliferation and migration of endothelial cells. Selectively promotes FGF-induced MAPK activation through SRC (By similarity); Belongs to the angiomotin family. | Receptor-like tyrosine kinase. | 0.557 |
| Amotl2 | Tmem108 | ENSRNOP00000075540 | ENSRNOP00000014520 | Angiomotin-like protein 2; Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments. Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. Participates in angiogenesis. May play a role in the polarity, proliferation and migration of endothelial cells. Selectively promotes FGF-induced MAPK activation through SRC (By similarity); Belongs to the angiomotin family. | Transmembrane protein 108. | 0.551 |
| Ky | Amotl2 | ENSRNOP00000010992 | ENSRNOP00000075540 | Kyphoscoliosis (Predicted). | Angiomotin-like protein 2; Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments. Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. Participates in angiogenesis. May play a role in the polarity, proliferation and migration of endothelial cells. Selectively promotes FGF-induced MAPK activation through SRC (By similarity); Belongs to the angiomotin family. | 0.581 |
| Ky | Lmod3 | ENSRNOP00000010992 | ENSRNOP00000042274 | Kyphoscoliosis (Predicted). | Leiomodin 3. | 0.587 |
| Ky | Mss51 | ENSRNOP00000010992 | ENSRNOP00000010179 | Kyphoscoliosis (Predicted). | Putative protein MSS51 homolog, mitochondrial. | 0.620 |
| Ky | Myl1 | ENSRNOP00000010992 | ENSRNOP00000017838 | Kyphoscoliosis (Predicted). | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. | 0.510 |
| Ky | Rab6b | ENSRNOP00000010992 | ENSRNOP00000068600 | Kyphoscoliosis (Predicted). | RAB6B, member RAS oncogene family. | 0.551 |
| Ky | Ryk | ENSRNOP00000010992 | ENSRNOP00000063141 | Kyphoscoliosis (Predicted). | Receptor-like tyrosine kinase. | 0.551 |
| Ky | Tmem108 | ENSRNOP00000010992 | ENSRNOP00000014520 | Kyphoscoliosis (Predicted). | Transmembrane protein 108. | 0.551 |
| Ky | Trim72 | ENSRNOP00000010992 | ENSRNOP00000030976 | Kyphoscoliosis (Predicted). | Tripartite motif-containing protein 72; Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Specifically binds phosphatidylserine. Acts as a sensor of oxidation: upon membrane damage, entry of extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site. This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation. Probably acts upstream of the Ca(2+)- depen [...] | 0.587 |
| Ky | Ttn | ENSRNOP00000010992 | ENSRNOP00000033967 | Kyphoscoliosis (Predicted). | Uncharacterized protein. | 0.602 |
| Ky | Wdr18 | ENSRNOP00000010992 | ENSRNOP00000016733 | Kyphoscoliosis (Predicted). | WD repeat-containing protein 18; Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes (By similarity). Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit (By similarity). | 0.510 |
| Lmod3 | Ky | ENSRNOP00000042274 | ENSRNOP00000010992 | Leiomodin 3. | Kyphoscoliosis (Predicted). | 0.587 |
| Lmod3 | Myl1 | ENSRNOP00000042274 | ENSRNOP00000017838 | Leiomodin 3. | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. | 0.537 |
| Lmod3 | Ttn | ENSRNOP00000042274 | ENSRNOP00000033967 | Leiomodin 3. | Uncharacterized protein. | 0.569 |
| Mss51 | Ky | ENSRNOP00000010179 | ENSRNOP00000010992 | Putative protein MSS51 homolog, mitochondrial. | Kyphoscoliosis (Predicted). | 0.620 |
| Myl1 | Ky | ENSRNOP00000017838 | ENSRNOP00000010992 | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. | Kyphoscoliosis (Predicted). | 0.510 |
| Myl1 | Lmod3 | ENSRNOP00000017838 | ENSRNOP00000042274 | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. | Leiomodin 3. | 0.537 |