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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Prg2Eosinophil granule major basic protein; Cytotoxin and helminthotoxin. MBP also induces non-cytolytic histamine release from basophils. It is involved in antiparasitic defense mechanisms and immune hypersensitivity reactions (By similarity). (227 aa)    
Predicted Functional Partners:
Pappa1
Pappalysin 1.
    
 
 0.903
Epx
Eosinophil peroxidase (Predicted).
   
  
 0.767
Prg3
Proteoglycan 3, pro eosinophil major basic protein 2.
  
  
0.634
Hspg2
Uncharacterized protein.
      
 0.605
Gzmbl1
Granszyme B-like 1; Belongs to the peptidase S1 family.
   
 
 0.552
Pappa2
Pappalysin 2.
   
 
 0.514
Rnase2
Pre-eosinophil-associated ribonuclease-2; Belongs to the pancreatic ribonuclease family.
   
  
 0.446
Rnase3
Eosinophil cationic protein; Cytotoxin and helminthotoxin with ribonuclease activity. Possesses a wide variety of biological activities (By similarity). Belongs to the pancreatic ribonuclease family.
   
  
 0.405
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.