node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Bcor | Cbx2 | ENSRNOP00000047677 | ENSRNOP00000067878 | BCL6 co-repressor. | Similar to chromobox homolog 2, isoform CRA_a. | 0.756 |
Bcor | Cbx7 | ENSRNOP00000047677 | ENSRNOP00000022631 | BCL6 co-repressor. | Chromobox protein homolog 7; Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to histone H3 trimethylated 'Lys-9' (H3K9me3) or at 'Lys-27' (H3K27me3). May possibly also bind trime [...] | 0.742 |
Bcor | Cbx8 | ENSRNOP00000047677 | ENSRNOP00000064273 | BCL6 co-repressor. | Chromobox homolog 8 (Drosophila, Pc class), isoform CRA_a. | 0.842 |
Bcor | Kdm2b | ENSRNOP00000047677 | ENSRNOP00000050408 | BCL6 co-repressor. | Lysine demethylase 2B. | 0.907 |
Bcor | Pcgf1 | ENSRNOP00000047677 | ENSRNOP00000011173 | BCL6 co-repressor. | Polycomb group RING finger protein 1; Component of the Polycomb group (PcG) multiprotein BCOR complex, a complex required to maintain the transcriptionally repressive state of some genes, such as BCL6 and the cyclin-dependent kinase inhibitor, CDKN1A. Transcriptional repressor that may be targeted to the DNA by BCL6; this transcription repressor activity may be related to PKC signaling pathway. Represses CDKN1A expression by binding to its promoter, and this repression is dependent on the retinoic acid response element (RARE element). Promotes cell cycle progression and enhances cell p [...] | 0.954 |
Bcor | Ring1 | ENSRNOP00000047677 | ENSRNOP00000000543 | BCL6 co-repressor. | E3 ubiquitin-protein ligase RING1; Constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. Essential component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG P [...] | 0.938 |
Bcor | Rnf2 | ENSRNOP00000047677 | ENSRNOP00000068794 | BCL6 co-repressor. | E3 ubiquitin-protein ligase RING2; E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-119' of histone H2A (H2AK119Ub), thereby playing a central role in histone code and gene regulation. H2AK119Ub gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. May be involved in the initiation of both imprinted and random X inactivation. Essential component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, i [...] | 0.968 |
Bcor | Rybp | ENSRNOP00000047677 | ENSRNOP00000007185 | BCL6 co-repressor. | RING1 and YY1-binding protein. | 0.809 |
Bcor | Skp1 | ENSRNOP00000047677 | ENSRNOP00000073214 | BCL6 co-repressor. | S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and participate in Wnt signaling. SCF(FBXW11) directs ubiquitination of phosphorylated NFKBIA. SCF(BTRC [...] | 0.751 |
Bcor | Yaf2 | ENSRNOP00000047677 | ENSRNOP00000006621 | BCL6 co-repressor. | YY1-associated factor 2. | 0.763 |
Cbx2 | Bcor | ENSRNOP00000067878 | ENSRNOP00000047677 | Similar to chromobox homolog 2, isoform CRA_a. | BCL6 co-repressor. | 0.756 |
Cbx2 | Cbx7 | ENSRNOP00000067878 | ENSRNOP00000022631 | Similar to chromobox homolog 2, isoform CRA_a. | Chromobox protein homolog 7; Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to histone H3 trimethylated 'Lys-9' (H3K9me3) or at 'Lys-27' (H3K27me3). May possibly also bind trime [...] | 0.882 |
Cbx2 | Cbx8 | ENSRNOP00000067878 | ENSRNOP00000064273 | Similar to chromobox homolog 2, isoform CRA_a. | Chromobox homolog 8 (Drosophila, Pc class), isoform CRA_a. | 0.954 |
Cbx2 | Kdm2b | ENSRNOP00000067878 | ENSRNOP00000050408 | Similar to chromobox homolog 2, isoform CRA_a. | Lysine demethylase 2B. | 0.400 |
Cbx2 | Pcgf1 | ENSRNOP00000067878 | ENSRNOP00000011173 | Similar to chromobox homolog 2, isoform CRA_a. | Polycomb group RING finger protein 1; Component of the Polycomb group (PcG) multiprotein BCOR complex, a complex required to maintain the transcriptionally repressive state of some genes, such as BCL6 and the cyclin-dependent kinase inhibitor, CDKN1A. Transcriptional repressor that may be targeted to the DNA by BCL6; this transcription repressor activity may be related to PKC signaling pathway. Represses CDKN1A expression by binding to its promoter, and this repression is dependent on the retinoic acid response element (RARE element). Promotes cell cycle progression and enhances cell p [...] | 0.946 |
Cbx2 | Ring1 | ENSRNOP00000067878 | ENSRNOP00000000543 | Similar to chromobox homolog 2, isoform CRA_a. | E3 ubiquitin-protein ligase RING1; Constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. Essential component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG P [...] | 0.973 |
Cbx2 | Rnf2 | ENSRNOP00000067878 | ENSRNOP00000068794 | Similar to chromobox homolog 2, isoform CRA_a. | E3 ubiquitin-protein ligase RING2; E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-119' of histone H2A (H2AK119Ub), thereby playing a central role in histone code and gene regulation. H2AK119Ub gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. May be involved in the initiation of both imprinted and random X inactivation. Essential component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, i [...] | 0.973 |
Cbx2 | Rybp | ENSRNOP00000067878 | ENSRNOP00000007185 | Similar to chromobox homolog 2, isoform CRA_a. | RING1 and YY1-binding protein. | 0.854 |
Cbx2 | Yaf2 | ENSRNOP00000067878 | ENSRNOP00000006621 | Similar to chromobox homolog 2, isoform CRA_a. | YY1-associated factor 2. | 0.825 |
Cbx7 | Bcor | ENSRNOP00000022631 | ENSRNOP00000047677 | Chromobox protein homolog 7; Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to histone H3 trimethylated 'Lys-9' (H3K9me3) or at 'Lys-27' (H3K27me3). May possibly also bind trime [...] | BCL6 co-repressor. | 0.742 |