Nanp protein (Rattus norvegicus) - STRING interaction network

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Your Current Organism:

Rattus norvegicus

NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cmahp	Cmas	ENSRNOP00000070006	ENSRNOP00000018734	Cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene.	N-acylneuraminate cytidylyltransferase; Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid. Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D- glycero-D-galacto-nononic acid (KDN) (By similarity).	0.912
Cmahp	Hoga1	ENSRNOP00000070006	ENSRNOP00000047674	Cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene.	Similar to RIKEN cDNA 0610010D20 (Predicted); Belongs to the DapA family.	0.822
Cmahp	Nanp	ENSRNOP00000070006	ENSRNOP00000011315	Cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene.	N-acylneuraminate-9-phosphatase; Belongs to the HAD-like hydrolase superfamily. NANP family.	0.918
Cmahp	Nans	ENSRNOP00000070006	ENSRNOP00000012260	Cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene.	N-acetylneuraminic acid synthase (Sialic acid synthase) (Predicted), isoform CRA_a.	0.929
Cmahp	Npl	ENSRNOP00000070006	ENSRNOP00000003713	Cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene.	N-acetylneuraminate lyase; Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate. It prevents sialic acids from being recycled and returning to the cell surface. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway (By similarity).	0.872
Cmahp	St3gal3	ENSRNOP00000070006	ENSRNOP00000053685	Cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene.	CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase soluble form; Catalyzes the formation of the NeuAc-alpha-2,3-Gal-beta-1,4- GlcNAc-, NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- and NeuAc-alpha-2,3-Gal- beta-1,3-GalNAc- sequences found in terminal carbohydrate groups of glycoproteins and glycolipids. The highest activity is toward Gal-beta- 1,3-GlcNAc and the lowest toward Gal-beta-1,3-GalNAc. Belongs to the glycosyltransferase 29 family.	0.455
Cmas	Cmahp	ENSRNOP00000018734	ENSRNOP00000070006	N-acylneuraminate cytidylyltransferase; Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid. Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D- glycero-D-galacto-nononic acid (KDN) (By similarity).	Cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene.	0.912
Cmas	Gne	ENSRNOP00000018734	ENSRNOP00000074334	N-acylneuraminate cytidylyltransferase; Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid. Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D- glycero-D-galacto-nononic acid (KDN) (By similarity).	Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase; Regulates and initiates biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. Required for normal sialylation in hematopoietic cells. Sialylation is implicated in cell adhesion, signal transduction, tumorigenicity and metastatic behavior of malignant cells. Plays an essential role in early development (By similarity); In the N-terminal section; belongs to the UDP-N- acetylglucosamine 2-epimerase family.	0.588
Cmas	Hoga1	ENSRNOP00000018734	ENSRNOP00000047674	N-acylneuraminate cytidylyltransferase; Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid. Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D- glycero-D-galacto-nononic acid (KDN) (By similarity).	Similar to RIKEN cDNA 0610010D20 (Predicted); Belongs to the DapA family.	0.843
Cmas	Nanp	ENSRNOP00000018734	ENSRNOP00000011315	N-acylneuraminate cytidylyltransferase; Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid. Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D- glycero-D-galacto-nononic acid (KDN) (By similarity).	N-acylneuraminate-9-phosphatase; Belongs to the HAD-like hydrolase superfamily. NANP family.	0.964
Cmas	Nans	ENSRNOP00000018734	ENSRNOP00000012260	N-acylneuraminate cytidylyltransferase; Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid. Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D- glycero-D-galacto-nononic acid (KDN) (By similarity).	N-acetylneuraminic acid synthase (Sialic acid synthase) (Predicted), isoform CRA_a.	0.997
Cmas	Npl	ENSRNOP00000018734	ENSRNOP00000003713	N-acylneuraminate cytidylyltransferase; Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid. Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D- glycero-D-galacto-nononic acid (KDN) (By similarity).	N-acetylneuraminate lyase; Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate. It prevents sialic acids from being recycled and returning to the cell surface. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway (By similarity).	0.921
Cmas	St3gal3	ENSRNOP00000018734	ENSRNOP00000053685	N-acylneuraminate cytidylyltransferase; Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid. Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D- glycero-D-galacto-nononic acid (KDN) (By similarity).	CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase soluble form; Catalyzes the formation of the NeuAc-alpha-2,3-Gal-beta-1,4- GlcNAc-, NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- and NeuAc-alpha-2,3-Gal- beta-1,3-GalNAc- sequences found in terminal carbohydrate groups of glycoproteins and glycolipids. The highest activity is toward Gal-beta- 1,3-GlcNAc and the lowest toward Gal-beta-1,3-GalNAc. Belongs to the glycosyltransferase 29 family.	0.417
Gne	Cmas	ENSRNOP00000074334	ENSRNOP00000018734	Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase; Regulates and initiates biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. Required for normal sialylation in hematopoietic cells. Sialylation is implicated in cell adhesion, signal transduction, tumorigenicity and metastatic behavior of malignant cells. Plays an essential role in early development (By similarity); In the N-terminal section; belongs to the UDP-N- acetylglucosamine 2-epimerase family.	N-acylneuraminate cytidylyltransferase; Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid. Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D- glycero-D-galacto-nononic acid (KDN) (By similarity).	0.588
Gne	Hoga1	ENSRNOP00000074334	ENSRNOP00000047674	Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase; Regulates and initiates biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. Required for normal sialylation in hematopoietic cells. Sialylation is implicated in cell adhesion, signal transduction, tumorigenicity and metastatic behavior of malignant cells. Plays an essential role in early development (By similarity); In the N-terminal section; belongs to the UDP-N- acetylglucosamine 2-epimerase family.	Similar to RIKEN cDNA 0610010D20 (Predicted); Belongs to the DapA family.	0.800
Gne	Nanp	ENSRNOP00000074334	ENSRNOP00000011315	Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase; Regulates and initiates biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. Required for normal sialylation in hematopoietic cells. Sialylation is implicated in cell adhesion, signal transduction, tumorigenicity and metastatic behavior of malignant cells. Plays an essential role in early development (By similarity); In the N-terminal section; belongs to the UDP-N- acetylglucosamine 2-epimerase family.	N-acylneuraminate-9-phosphatase; Belongs to the HAD-like hydrolase superfamily. NANP family.	0.766
Gne	Nans	ENSRNOP00000074334	ENSRNOP00000012260	Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase; Regulates and initiates biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. Required for normal sialylation in hematopoietic cells. Sialylation is implicated in cell adhesion, signal transduction, tumorigenicity and metastatic behavior of malignant cells. Plays an essential role in early development (By similarity); In the N-terminal section; belongs to the UDP-N- acetylglucosamine 2-epimerase family.	N-acetylneuraminic acid synthase (Sialic acid synthase) (Predicted), isoform CRA_a.	0.977
Gne	Npl	ENSRNOP00000074334	ENSRNOP00000003713	Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase; Regulates and initiates biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. Required for normal sialylation in hematopoietic cells. Sialylation is implicated in cell adhesion, signal transduction, tumorigenicity and metastatic behavior of malignant cells. Plays an essential role in early development (By similarity); In the N-terminal section; belongs to the UDP-N- acetylglucosamine 2-epimerase family.	N-acetylneuraminate lyase; Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate. It prevents sialic acids from being recycled and returning to the cell surface. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway (By similarity).	0.920
Gne	St3gal3	ENSRNOP00000074334	ENSRNOP00000053685	Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase; Regulates and initiates biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. Required for normal sialylation in hematopoietic cells. Sialylation is implicated in cell adhesion, signal transduction, tumorigenicity and metastatic behavior of malignant cells. Plays an essential role in early development (By similarity); In the N-terminal section; belongs to the UDP-N- acetylglucosamine 2-epimerase family.	CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase soluble form; Catalyzes the formation of the NeuAc-alpha-2,3-Gal-beta-1,4- GlcNAc-, NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- and NeuAc-alpha-2,3-Gal- beta-1,3-GalNAc- sequences found in terminal carbohydrate groups of glycoproteins and glycolipids. The highest activity is toward Gal-beta- 1,3-GlcNAc and the lowest toward Gal-beta-1,3-GalNAc. Belongs to the glycosyltransferase 29 family.	0.511
Hoga1	Cmahp	ENSRNOP00000047674	ENSRNOP00000070006	Similar to RIKEN cDNA 0610010D20 (Predicted); Belongs to the DapA family.	Cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene.	0.822

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