STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Chrac1Chromatin accessibility complex 1 (Predicted), isoform CRA_b. (128 aa)    
Predicted Functional Partners:
LOC100362333
DNA polymerase epsilon subunit 3; Accessory component of the DNA polymerase epsilon complex (By similarity). Participates in DNA repair and in chromosomal DNA replication (By similarity). Forms a complex with CHRAC1 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome-remodeling activity of ISWI/SNF2H and ACF1 (By similarity).
    
 0.983
Pole3
DNA-directed DNA polymerase epsilon 3.
   
 0.980
Baz1a
Bromodomain adjacent to zinc finger domain, 1A.
   
 0.971
Smarca5
SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily a, member 5.
    
 0.936
M0R882_RAT
Uncharacterized protein.
    
 0.910
Nfyb
Nuclear transcription factor Y subunit beta; Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors.
   
 
 0.869
Nfya
Nuclear transcription factor Y subunit alpha; Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors. NF-YA positively regulates the transcription of the core clock component ARNTL/BMAL1; Belongs to the NFYA/HAP2 subunit family.
    
 
 0.866
Smarca1
SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily a, member 1.
    
 0.843
Baz1b
Bromodomain adjacent to zinc finger domain protein 1B.
   
 0.755
Coa5
Cytochrome C oxidase assembly factor 5.
      
 0.741
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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