node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Abcb7 | Abcb8 | ENSRNOP00000003739 | ENSRNOP00000012222 | Atp-binding cassette, subfamily b (mdr/tap), member 7; Could be involved in the transport of heme from the mitochondria to the cytosol. Plays a central role in the maturation of cytosolic iron-sulfur (Fe/S) cluster-containing proteins | Atp-binding cassette sub-family b member 8, mitochondrial; ATP-binding cassette, subfamily B (MDR/TAP), member 8 | 0.753 |
Abcb7 | Abce1 | ENSRNOP00000003739 | ENSRNOP00000024753 | Atp-binding cassette, subfamily b (mdr/tap), member 7; Could be involved in the transport of heme from the mitochondria to the cytosol. Plays a central role in the maturation of cytosolic iron-sulfur (Fe/S) cluster-containing proteins | ATP-binding cassette, subfamily E (OABP), member 1 | 0.647 |
Abcb7 | Abcf1 | ENSRNOP00000003739 | ENSRNOP00000001049 | Atp-binding cassette, subfamily b (mdr/tap), member 7; Could be involved in the transport of heme from the mitochondria to the cytosol. Plays a central role in the maturation of cytosolic iron-sulfur (Fe/S) cluster-containing proteins | Atp-binding cassette, subfamily f, member 1; ATP-binding cassette sub-family F member 1; Required for efficient Cap- and IRES-mediated mRNA translation initiation. Not involved in the ribosome biogenesis (By similarity) | 0.686 |
Abcb7 | Fech | ENSRNOP00000003739 | ENSRNOP00000024328 | Atp-binding cassette, subfamily b (mdr/tap), member 7; Could be involved in the transport of heme from the mitochondria to the cytosol. Plays a central role in the maturation of cytosolic iron-sulfur (Fe/S) cluster-containing proteins | Protoporphyrin/coproporphyrin ferrochelatase; Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX | 0.974 |
Abcb7 | Fxn | ENSRNOP00000003739 | ENSRNOP00000020412 | Atp-binding cassette, subfamily b (mdr/tap), member 7; Could be involved in the transport of heme from the mitochondria to the cytosol. Plays a central role in the maturation of cytosolic iron-sulfur (Fe/S) cluster-containing proteins | Frataxin intermediate form; Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+); the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Modulates the RNA-binding activity of ACO1 (By similarity) | 0.868 |
Abcb7 | Ppox | ENSRNOP00000003739 | ENSRNOP00000004896 | Atp-binding cassette, subfamily b (mdr/tap), member 7; Could be involved in the transport of heme from the mitochondria to the cytosol. Plays a central role in the maturation of cytosolic iron-sulfur (Fe/S) cluster-containing proteins | Protoporphyrinogen/coproporphyrinogen iii oxidase; Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX | 0.688 |
Abcb7 | Slc25a37 | ENSRNOP00000003739 | ENSRNOP00000021636 | Atp-binding cassette, subfamily b (mdr/tap), member 7; Could be involved in the transport of heme from the mitochondria to the cytosol. Plays a central role in the maturation of cytosolic iron-sulfur (Fe/S) cluster-containing proteins | Solute carrier family 25 (mitochondrial iron transporter), member 28/37; Mitoferrin-1; Mitochondrial iron transporter that specifically mediates iron uptake in developing erythroid cells, thereby playing an essential role in heme biosynthesis. The iron delivered into the mitochondria, presumably as Fe(2+), is then probably delivered to ferrochelatase to catalyze Fe(2+) incorporation into protoprophyrin IX to make heme (By similarity) | 0.801 |
Abcb8 | Abcb7 | ENSRNOP00000012222 | ENSRNOP00000003739 | Atp-binding cassette sub-family b member 8, mitochondrial; ATP-binding cassette, subfamily B (MDR/TAP), member 8 | Atp-binding cassette, subfamily b (mdr/tap), member 7; Could be involved in the transport of heme from the mitochondria to the cytosol. Plays a central role in the maturation of cytosolic iron-sulfur (Fe/S) cluster-containing proteins | 0.753 |
Abcb8 | Abce1 | ENSRNOP00000012222 | ENSRNOP00000024753 | Atp-binding cassette sub-family b member 8, mitochondrial; ATP-binding cassette, subfamily B (MDR/TAP), member 8 | ATP-binding cassette, subfamily E (OABP), member 1 | 0.670 |
Abcb8 | Abcf1 | ENSRNOP00000012222 | ENSRNOP00000001049 | Atp-binding cassette sub-family b member 8, mitochondrial; ATP-binding cassette, subfamily B (MDR/TAP), member 8 | Atp-binding cassette, subfamily f, member 1; ATP-binding cassette sub-family F member 1; Required for efficient Cap- and IRES-mediated mRNA translation initiation. Not involved in the ribosome biogenesis (By similarity) | 0.512 |
Abcb8 | Dtwd1 | ENSRNOP00000012222 | ENSRNOP00000012966 | Atp-binding cassette sub-family b member 8, mitochondrial; ATP-binding cassette, subfamily B (MDR/TAP), member 8 | DTW domain containing 1 | 0.572 |
Abcb8 | Fech | ENSRNOP00000012222 | ENSRNOP00000024328 | Atp-binding cassette sub-family b member 8, mitochondrial; ATP-binding cassette, subfamily B (MDR/TAP), member 8 | Protoporphyrin/coproporphyrin ferrochelatase; Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX | 0.582 |
Abcb8 | Fxn | ENSRNOP00000012222 | ENSRNOP00000020412 | Atp-binding cassette sub-family b member 8, mitochondrial; ATP-binding cassette, subfamily B (MDR/TAP), member 8 | Frataxin intermediate form; Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+); the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Modulates the RNA-binding activity of ACO1 (By similarity) | 0.570 |
Abcb8 | Ppox | ENSRNOP00000012222 | ENSRNOP00000004896 | Atp-binding cassette sub-family b member 8, mitochondrial; ATP-binding cassette, subfamily B (MDR/TAP), member 8 | Protoporphyrinogen/coproporphyrinogen iii oxidase; Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX | 0.494 |
Abcb8 | Slc25a37 | ENSRNOP00000012222 | ENSRNOP00000021636 | Atp-binding cassette sub-family b member 8, mitochondrial; ATP-binding cassette, subfamily B (MDR/TAP), member 8 | Solute carrier family 25 (mitochondrial iron transporter), member 28/37; Mitoferrin-1; Mitochondrial iron transporter that specifically mediates iron uptake in developing erythroid cells, thereby playing an essential role in heme biosynthesis. The iron delivered into the mitochondria, presumably as Fe(2+), is then probably delivered to ferrochelatase to catalyze Fe(2+) incorporation into protoprophyrin IX to make heme (By similarity) | 0.513 |
Abcb8 | Slc35e3 | ENSRNOP00000012222 | ENSRNOP00000031609 | Atp-binding cassette sub-family b member 8, mitochondrial; ATP-binding cassette, subfamily B (MDR/TAP), member 8 | Solute carrier family 35, member E3 | 0.541 |
Abcb8 | Tmem196 | ENSRNOP00000012222 | ENSRNOP00000053487 | Atp-binding cassette sub-family b member 8, mitochondrial; ATP-binding cassette, subfamily B (MDR/TAP), member 8 | Transmembrane protein 196 | 0.503 |
Abce1 | Abcb7 | ENSRNOP00000024753 | ENSRNOP00000003739 | ATP-binding cassette, subfamily E (OABP), member 1 | Atp-binding cassette, subfamily b (mdr/tap), member 7; Could be involved in the transport of heme from the mitochondria to the cytosol. Plays a central role in the maturation of cytosolic iron-sulfur (Fe/S) cluster-containing proteins | 0.647 |
Abce1 | Abcb8 | ENSRNOP00000024753 | ENSRNOP00000012222 | ATP-binding cassette, subfamily E (OABP), member 1 | Atp-binding cassette sub-family b member 8, mitochondrial; ATP-binding cassette, subfamily B (MDR/TAP), member 8 | 0.670 |
Abce1 | Abcf1 | ENSRNOP00000024753 | ENSRNOP00000001049 | ATP-binding cassette, subfamily E (OABP), member 1 | Atp-binding cassette, subfamily f, member 1; ATP-binding cassette sub-family F member 1; Required for efficient Cap- and IRES-mediated mRNA translation initiation. Not involved in the ribosome biogenesis (By similarity) | 0.873 |