node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cntfr | Il12a | ENSRNOP00000066185 | ENSRNOP00000012832 | Ciliary neurotrophic factor receptor subunit alpha; Binds to CNTF. The alpha subunit provides the receptor specificity. | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. | 0.755 |
Cntfr | Il12b | ENSRNOP00000066185 | ENSRNOP00000005898 | Ciliary neurotrophic factor receptor subunit alpha; Binds to CNTF. The alpha subunit provides the receptor specificity. | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. | 0.679 |
Cntfr | Il12rb2 | ENSRNOP00000066185 | ENSRNOP00000009883 | Ciliary neurotrophic factor receptor subunit alpha; Binds to CNTF. The alpha subunit provides the receptor specificity. | Interleukin 12 receptor subunit beta 2. | 0.419 |
Cntfr | Il23a | ENSRNOP00000066185 | ENSRNOP00000004363 | Ciliary neurotrophic factor receptor subunit alpha; Binds to CNTF. The alpha subunit provides the receptor specificity. | Interleukin-23 subunit alpha; Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tu [...] | 0.693 |
Ifnar1 | Ifngr1 | ENSRNOP00000031611 | ENSRNOP00000016286 | Interferon (Alpha and beta) receptor 1 (Predicted), isoform CRA_a. | Interferon gamma receptor 1. | 0.982 |
Ifnar1 | Il12a | ENSRNOP00000031611 | ENSRNOP00000012832 | Interferon (Alpha and beta) receptor 1 (Predicted), isoform CRA_a. | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. | 0.759 |
Ifnar1 | Il12b | ENSRNOP00000031611 | ENSRNOP00000005898 | Interferon (Alpha and beta) receptor 1 (Predicted), isoform CRA_a. | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. | 0.796 |
Ifnar1 | Il22ra1 | ENSRNOP00000031611 | ENSRNOP00000037743 | Interferon (Alpha and beta) receptor 1 (Predicted), isoform CRA_a. | Interleukin 22 receptor subunit alpha 1. | 0.584 |
Ifnar1 | Il23a | ENSRNOP00000031611 | ENSRNOP00000004363 | Interferon (Alpha and beta) receptor 1 (Predicted), isoform CRA_a. | Interleukin-23 subunit alpha; Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tu [...] | 0.710 |
Ifngr1 | Ifnar1 | ENSRNOP00000016286 | ENSRNOP00000031611 | Interferon gamma receptor 1. | Interferon (Alpha and beta) receptor 1 (Predicted), isoform CRA_a. | 0.982 |
Ifngr1 | Il12a | ENSRNOP00000016286 | ENSRNOP00000012832 | Interferon gamma receptor 1. | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. | 0.837 |
Ifngr1 | Il12b | ENSRNOP00000016286 | ENSRNOP00000005898 | Interferon gamma receptor 1. | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. | 0.867 |
Ifngr1 | Il12rb1 | ENSRNOP00000016286 | ENSRNOP00000025977 | Interferon gamma receptor 1. | Interleukin 12 receptor subunit beta 1. | 0.626 |
Ifngr1 | Il12rb2 | ENSRNOP00000016286 | ENSRNOP00000009883 | Interferon gamma receptor 1. | Interleukin 12 receptor subunit beta 2. | 0.549 |
Ifngr1 | Il23a | ENSRNOP00000016286 | ENSRNOP00000004363 | Interferon gamma receptor 1. | Interleukin-23 subunit alpha; Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tu [...] | 0.714 |
Il12a | Cntfr | ENSRNOP00000012832 | ENSRNOP00000066185 | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. | Ciliary neurotrophic factor receptor subunit alpha; Binds to CNTF. The alpha subunit provides the receptor specificity. | 0.755 |
Il12a | Ifnar1 | ENSRNOP00000012832 | ENSRNOP00000031611 | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. | Interferon (Alpha and beta) receptor 1 (Predicted), isoform CRA_a. | 0.759 |
Il12a | Ifngr1 | ENSRNOP00000012832 | ENSRNOP00000016286 | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. | Interferon gamma receptor 1. | 0.837 |
Il12a | Il12b | ENSRNOP00000012832 | ENSRNOP00000005898 | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. | 0.998 |
Il12a | Il12rb1 | ENSRNOP00000012832 | ENSRNOP00000025977 | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. | Interleukin 12 receptor subunit beta 1. | 0.975 |