Pnma2 protein (Rattus norvegicus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

Pnma2

PNMA family member 2. (364 aa)

Predicted Functional Partners:

Zic4

0.756

Dner

0.665

Rcvrn

0.656

Arhgap26

0.646

Rtl6

0.646

Pnma8a

0.628

Amph

0.624

Lgi1

0.622

Dpp10

0.606

Dpp6

0.587

Your Current Organism:

Rattus norvegicus

NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Amph	Arhgap26	ENSRNOP00000017102	ENSRNOP00000018843	Amphiphysin; May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton (By similarity).	Rho GTPase activating protein 26 (Predicted).	0.711
Amph	Dner	ENSRNOP00000017102	ENSRNOP00000076139	Amphiphysin; May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton (By similarity).	Delta/notch-like EGF repeat-containing.	0.821
Amph	Dpp10	ENSRNOP00000017102	ENSRNOP00000003527	Amphiphysin; May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton (By similarity).	Inactive dipeptidyl peptidase 10; Promotes cell surface expression of the potassium channel KCND2. Modulates the activity and gating characteristics of the potassium channel KCND2. Has no dipeptidyl aminopeptidase activity (Probable).	0.768
Amph	Dpp6	ENSRNOP00000017102	ENSRNOP00000043113	Amphiphysin; May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton (By similarity).	Dipeptidyl aminopeptidase-like protein 6; Promotes cell surface expression of the potassium channel KCND2. Modulates the activity and gating characteristics of the potassium channel KCND2. Has no dipeptidyl aminopeptidase activity (By similarity). Belongs to the peptidase S9B family.	0.824
Amph	Lgi1	ENSRNOP00000017102	ENSRNOP00000020411	Amphiphysin; May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton (By similarity).	Leucine-rich glioma-inactivated protein 1; Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway (By similarity). Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors.	0.827
Amph	Pnma2	ENSRNOP00000017102	ENSRNOP00000013001	Amphiphysin; May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton (By similarity).	PNMA family member 2.	0.624
Amph	Rcvrn	ENSRNOP00000017102	ENSRNOP00000004880	Amphiphysin; May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton (By similarity).	Recoverin.	0.740
Amph	Zic4	ENSRNOP00000017102	ENSRNOP00000019938	Amphiphysin; May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton (By similarity).	Zic family member 4.	0.804
Arhgap26	Amph	ENSRNOP00000018843	ENSRNOP00000017102	Rho GTPase activating protein 26 (Predicted).	Amphiphysin; May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton (By similarity).	0.711
Arhgap26	Dner	ENSRNOP00000018843	ENSRNOP00000076139	Rho GTPase activating protein 26 (Predicted).	Delta/notch-like EGF repeat-containing.	0.810
Arhgap26	Dpp10	ENSRNOP00000018843	ENSRNOP00000003527	Rho GTPase activating protein 26 (Predicted).	Inactive dipeptidyl peptidase 10; Promotes cell surface expression of the potassium channel KCND2. Modulates the activity and gating characteristics of the potassium channel KCND2. Has no dipeptidyl aminopeptidase activity (Probable).	0.630
Arhgap26	Dpp6	ENSRNOP00000018843	ENSRNOP00000043113	Rho GTPase activating protein 26 (Predicted).	Dipeptidyl aminopeptidase-like protein 6; Promotes cell surface expression of the potassium channel KCND2. Modulates the activity and gating characteristics of the potassium channel KCND2. Has no dipeptidyl aminopeptidase activity (By similarity). Belongs to the peptidase S9B family.	0.637
Arhgap26	Lgi1	ENSRNOP00000018843	ENSRNOP00000020411	Rho GTPase activating protein 26 (Predicted).	Leucine-rich glioma-inactivated protein 1; Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway (By similarity). Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors.	0.724
Arhgap26	Pnma2	ENSRNOP00000018843	ENSRNOP00000013001	Rho GTPase activating protein 26 (Predicted).	PNMA family member 2.	0.646
Arhgap26	Rcvrn	ENSRNOP00000018843	ENSRNOP00000004880	Rho GTPase activating protein 26 (Predicted).	Recoverin.	0.611
Arhgap26	Zic4	ENSRNOP00000018843	ENSRNOP00000019938	Rho GTPase activating protein 26 (Predicted).	Zic family member 4.	0.765
Dner	Amph	ENSRNOP00000076139	ENSRNOP00000017102	Delta/notch-like EGF repeat-containing.	Amphiphysin; May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton (By similarity).	0.821
Dner	Arhgap26	ENSRNOP00000076139	ENSRNOP00000018843	Delta/notch-like EGF repeat-containing.	Rho GTPase activating protein 26 (Predicted).	0.810
Dner	Dpp10	ENSRNOP00000076139	ENSRNOP00000003527	Delta/notch-like EGF repeat-containing.	Inactive dipeptidyl peptidase 10; Promotes cell surface expression of the potassium channel KCND2. Modulates the activity and gating characteristics of the potassium channel KCND2. Has no dipeptidyl aminopeptidase activity (Probable).	0.765
Dner	Dpp6	ENSRNOP00000076139	ENSRNOP00000043113	Delta/notch-like EGF repeat-containing.	Dipeptidyl aminopeptidase-like protein 6; Promotes cell surface expression of the potassium channel KCND2. Modulates the activity and gating characteristics of the potassium channel KCND2. Has no dipeptidyl aminopeptidase activity (By similarity). Belongs to the peptidase S9B family.	0.771

page 1 of 4

Server load: low (12%) [HD]

Permalink

Network

Co-occurrence

Experiments

Co-expression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About