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Nos3 protein (Rattus norvegicus) - STRING interaction network
"Nos3" - Nitric oxide synthase, endothelial in Rattus norvegicus
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Nos3Nitric oxide synthase, endothelial ; Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets (1202 aa)    
Predicted Functional Partners:
Calm1
Calmodulin ; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity) (149 aa)
       
  0.998
Akt1
RAC-alpha serine/threonine-protein kinase ; AKT1 is one of 3 closely related serine/threonine- protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation of t [...] (480 aa)
     
  0.989
Papss2
Bifunctional 3’-phosphoadenosine 5’-phosphosulfate synthase 2 (614 aa)
   
  0.981
Papss1
Bifunctional 3’-phosphoadenosine 5’-phosphosulfate synthase 1 (599 aa)
   
  0.981
Calml3
Calmodulin-like protein 3 ; May function as a specific light chain of unconventional myosin-10 (MYO10), also enhances MYO10 translation, possibly by acting as a chaperone for the emerging MYO10 heavy chain protein. May compete with calmodulin by binding, with different affinities, to cellular substrates (By similarity) (149 aa)
       
  0.966
Calm4
Protein Calm4 (147 aa)
       
  0.966
ENSRNOG00000016770
Calmodulin (149 aa)
       
 
  0.966
Asl
Argininosuccinate lyase (464 aa)
     
 
  0.966
Ass1
Argininosuccinate synthase ; Is indirectly involved in the control of blood pressure (412 aa)
     
 
  0.964
Arg1
Arginase-1 (323 aa)
     
  0.948
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Gunn rats, Norway rat, R. norvegicus, Rattus, Rattus PC12 clone IS, Rattus norvegicus, Rattus rattiscus, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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