node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Hes7 | Lfng | ENSRNOP00000009757 | ENSRNOP00000001682 | Hairy and enhancer of split 7 (Drosophila) (Predicted). | Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe; Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Modulates NOTCH1 activity by modifying O- fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1. Decreases the binding of JAG1 to NOTCH2 but not that of DLL1. Essential mediator of somite segmentation and patterning. | 0.693 |
Hes7 | Mesp2 | ENSRNOP00000009757 | ENSRNOP00000020047 | Hairy and enhancer of split 7 (Drosophila) (Predicted). | Mesoderm posterior bHLH transcription factor 2. | 0.703 |
Hes7 | Ripply2 | ENSRNOP00000009757 | ENSRNOP00000013285 | Hairy and enhancer of split 7 (Drosophila) (Predicted). | Ripply transcriptional repressor 2. | 0.600 |
Hes7 | Tbx6 | ENSRNOP00000009757 | ENSRNOP00000060687 | Hairy and enhancer of split 7 (Drosophila) (Predicted). | T-box transcription factor TBX6; T-box transcription factor that plays an essential role in the determination of the fate of axial stem cells: neural vs mesodermal. Acts in part by down-regulating, a specific enhancer (N1) of SOX2, to inhibit neural development. Seems to also play an essential role in left/right axis determination and acts through effects on Notch signaling around the node as well as through an effect on the morphology and motility of the nodal cilia (By similarity). | 0.581 |
Hes7 | Uncx | ENSRNOP00000009757 | ENSRNOP00000001730 | Hairy and enhancer of split 7 (Drosophila) (Predicted). | Homeobox protein unc-4 homolog; Transcription factor involved in somitogenesis and neurogenesis. Required for the maintenance and differentiation of particular elements of the axial skeleton. May act upstream of PAX9. Plays a role in controlling the development of connections of hypothalamic neurons to pituitary elements, allowing central neurons to reach the peripheral blood circulation and to deliver hormones for control of peripheral functions (By similarity). | 0.479 |
Kiaa0408L | Ripply2 | ENSRNOP00000035937 | ENSRNOP00000013285 | RCG42077, isoform CRA_b. | Ripply transcriptional repressor 2. | 0.658 |
Lfng | Hes7 | ENSRNOP00000001682 | ENSRNOP00000009757 | Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe; Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Modulates NOTCH1 activity by modifying O- fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1. Decreases the binding of JAG1 to NOTCH2 but not that of DLL1. Essential mediator of somite segmentation and patterning. | Hairy and enhancer of split 7 (Drosophila) (Predicted). | 0.693 |
Lfng | Mesp2 | ENSRNOP00000001682 | ENSRNOP00000020047 | Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe; Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Modulates NOTCH1 activity by modifying O- fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1. Decreases the binding of JAG1 to NOTCH2 but not that of DLL1. Essential mediator of somite segmentation and patterning. | Mesoderm posterior bHLH transcription factor 2. | 0.733 |
Lfng | Ripply2 | ENSRNOP00000001682 | ENSRNOP00000013285 | Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe; Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Modulates NOTCH1 activity by modifying O- fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1. Decreases the binding of JAG1 to NOTCH2 but not that of DLL1. Essential mediator of somite segmentation and patterning. | Ripply transcriptional repressor 2. | 0.549 |
Lfng | Tbx6 | ENSRNOP00000001682 | ENSRNOP00000060687 | Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe; Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Modulates NOTCH1 activity by modifying O- fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1. Decreases the binding of JAG1 to NOTCH2 but not that of DLL1. Essential mediator of somite segmentation and patterning. | T-box transcription factor TBX6; T-box transcription factor that plays an essential role in the determination of the fate of axial stem cells: neural vs mesodermal. Acts in part by down-regulating, a specific enhancer (N1) of SOX2, to inhibit neural development. Seems to also play an essential role in left/right axis determination and acts through effects on Notch signaling around the node as well as through an effect on the morphology and motility of the nodal cilia (By similarity). | 0.540 |
Lfng | Uncx | ENSRNOP00000001682 | ENSRNOP00000001730 | Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe; Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Modulates NOTCH1 activity by modifying O- fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1. Decreases the binding of JAG1 to NOTCH2 but not that of DLL1. Essential mediator of somite segmentation and patterning. | Homeobox protein unc-4 homolog; Transcription factor involved in somitogenesis and neurogenesis. Required for the maintenance and differentiation of particular elements of the axial skeleton. May act upstream of PAX9. Plays a role in controlling the development of connections of hypothalamic neurons to pituitary elements, allowing central neurons to reach the peripheral blood circulation and to deliver hormones for control of peripheral functions (By similarity). | 0.635 |
Mesp2 | Hes7 | ENSRNOP00000020047 | ENSRNOP00000009757 | Mesoderm posterior bHLH transcription factor 2. | Hairy and enhancer of split 7 (Drosophila) (Predicted). | 0.703 |
Mesp2 | Lfng | ENSRNOP00000020047 | ENSRNOP00000001682 | Mesoderm posterior bHLH transcription factor 2. | Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe; Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Modulates NOTCH1 activity by modifying O- fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1. Decreases the binding of JAG1 to NOTCH2 but not that of DLL1. Essential mediator of somite segmentation and patterning. | 0.733 |
Mesp2 | Ripply2 | ENSRNOP00000020047 | ENSRNOP00000013285 | Mesoderm posterior bHLH transcription factor 2. | Ripply transcriptional repressor 2. | 0.801 |
Mesp2 | Tbx6 | ENSRNOP00000020047 | ENSRNOP00000060687 | Mesoderm posterior bHLH transcription factor 2. | T-box transcription factor TBX6; T-box transcription factor that plays an essential role in the determination of the fate of axial stem cells: neural vs mesodermal. Acts in part by down-regulating, a specific enhancer (N1) of SOX2, to inhibit neural development. Seems to also play an essential role in left/right axis determination and acts through effects on Notch signaling around the node as well as through an effect on the morphology and motility of the nodal cilia (By similarity). | 0.794 |
Mesp2 | Uncx | ENSRNOP00000020047 | ENSRNOP00000001730 | Mesoderm posterior bHLH transcription factor 2. | Homeobox protein unc-4 homolog; Transcription factor involved in somitogenesis and neurogenesis. Required for the maintenance and differentiation of particular elements of the axial skeleton. May act upstream of PAX9. Plays a role in controlling the development of connections of hypothalamic neurons to pituitary elements, allowing central neurons to reach the peripheral blood circulation and to deliver hormones for control of peripheral functions (By similarity). | 0.672 |
Msgn1 | Ripply2 | ENSRNOP00000006482 | ENSRNOP00000013285 | Mesogenin 1. | Ripply transcriptional repressor 2. | 0.562 |
Msgn1 | Tbx6 | ENSRNOP00000006482 | ENSRNOP00000060687 | Mesogenin 1. | T-box transcription factor TBX6; T-box transcription factor that plays an essential role in the determination of the fate of axial stem cells: neural vs mesodermal. Acts in part by down-regulating, a specific enhancer (N1) of SOX2, to inhibit neural development. Seems to also play an essential role in left/right axis determination and acts through effects on Notch signaling around the node as well as through an effect on the morphology and motility of the nodal cilia (By similarity). | 0.667 |
Ripply2 | Hes7 | ENSRNOP00000013285 | ENSRNOP00000009757 | Ripply transcriptional repressor 2. | Hairy and enhancer of split 7 (Drosophila) (Predicted). | 0.600 |
Ripply2 | Kiaa0408L | ENSRNOP00000013285 | ENSRNOP00000035937 | Ripply transcriptional repressor 2. | RCG42077, isoform CRA_b. | 0.658 |