Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Emc3ER membrane protein complex subunit 3; Belongs to the EMC3 family. (261 aa)    
Predicted Functional Partners:
Emc4
ER membrane protein complex subunit 4; Belongs to the EMC4 family.
   
 0.999
Mmgt1
Membrane magnesium transporter 1; Mediates Mg(2+) transport.
   
 0.998
Emc2
ER membrane protein complex subunit 2; Belongs to the EMC2 family.
   
 0.998
Emc7
ER membrane protein complex subunit 7.
   
 0.998
Emc8
ER membrane protein complex subunit 8; Belongs to the EMC8/EMC9 family.
   
 0.998
Emc9
ER membrane protein complex subunit 9; Belongs to the EMC8/EMC9 family.
   
 0.998
Emc6
ER membrane protein complex subunit 6.
   
 0.998
Emc10
ER membrane protein complex subunit 10; Promotes angiogenesis and tissue repair in the heart after myocardial infarction. Stimulates cardiac endothelial cell migration and outgrowth via the activation of p38 MAPK, PAK and MAPK2 signaling pathways.
   
 0.998
Emc1
Similar to KIAA0090 protein (Predicted), isoform CRA_a.
   
 0.998
Ubac2
Phosphoglycerate dehydrogenase like 1.
   
 
 0.871
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.