Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cd4 | Eomes | ENSRNOP00000021915 | ENSRNOP00000013530 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | Eomesodermin. | 0.845 |
| Cd4 | Gata3 | ENSRNOP00000021915 | ENSRNOP00000026187 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | GATA-binding protein 3. | 0.902 |
| Cd4 | Gzmb | ENSRNOP00000021915 | ENSRNOP00000040429 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | Granzyme B; This enzyme is necessary for target cell lysis in cell- mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis (By similarity); Belongs to the peptidase S1 family. Granzyme subfamily. | 0.904 |
| Cd4 | Gzmbl2 | ENSRNOP00000021915 | ENSRNOP00000056412 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | Granzyme B. | 0.907 |
| Cd4 | Gzmk | ENSRNOP00000021915 | ENSRNOP00000014319 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | Granzyme K; Belongs to the peptidase S1 family. Granzyme subfamily. | 0.612 |
| Cd4 | Klrg1 | ENSRNOP00000021915 | ENSRNOP00000020094 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | Killer cell lectin-like receptor subfamily G member 1; Plays an inhibitory role on natural killer (NK) cells and T- cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E- cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells (By similarity). | 0.836 |
| Cdx2 | Eomes | ENSRNOP00000045045 | ENSRNOP00000013530 | Caudal type homeo box 2. | Eomesodermin. | 0.792 |
| Cdx2 | Gata3 | ENSRNOP00000045045 | ENSRNOP00000026187 | Caudal type homeo box 2. | GATA-binding protein 3. | 0.569 |
| Cdx2 | Sox17 | ENSRNOP00000045045 | ENSRNOP00000033962 | Caudal type homeo box 2. | SRY-box containing gene 17 (Predicted), isoform CRA_a. | 0.675 |
| Eomes | Cd4 | ENSRNOP00000013530 | ENSRNOP00000021915 | Eomesodermin. | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | 0.845 |
| Eomes | Cdx2 | ENSRNOP00000013530 | ENSRNOP00000045045 | Eomesodermin. | Caudal type homeo box 2. | 0.792 |
| Eomes | Gata3 | ENSRNOP00000013530 | ENSRNOP00000026187 | Eomesodermin. | GATA-binding protein 3. | 0.795 |
| Eomes | Gzmb | ENSRNOP00000013530 | ENSRNOP00000040429 | Eomesodermin. | Granzyme B; This enzyme is necessary for target cell lysis in cell- mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis (By similarity); Belongs to the peptidase S1 family. Granzyme subfamily. | 0.818 |
| Eomes | Gzmbl2 | ENSRNOP00000013530 | ENSRNOP00000056412 | Eomesodermin. | Granzyme B. | 0.818 |
| Eomes | Gzmk | ENSRNOP00000013530 | ENSRNOP00000014319 | Eomesodermin. | Granzyme K; Belongs to the peptidase S1 family. Granzyme subfamily. | 0.792 |
| Eomes | Klrg1 | ENSRNOP00000013530 | ENSRNOP00000020094 | Eomesodermin. | Killer cell lectin-like receptor subfamily G member 1; Plays an inhibitory role on natural killer (NK) cells and T- cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E- cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells (By similarity). | 0.775 |
| Eomes | Mixl1 | ENSRNOP00000013530 | ENSRNOP00000004244 | Eomesodermin. | Mix paired-like homeobox 1. | 0.784 |
| Eomes | Mixl1-2 | ENSRNOP00000013530 | ENSRNOP00000064882 | Eomesodermin. | Mix paired-like homeobox. | 0.784 |
| Eomes | Sox17 | ENSRNOP00000013530 | ENSRNOP00000033962 | Eomesodermin. | SRY-box containing gene 17 (Predicted), isoform CRA_a. | 0.788 |
| Gata3 | Cd4 | ENSRNOP00000026187 | ENSRNOP00000021915 | GATA-binding protein 3. | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | 0.902 |
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