STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Foxb1Forkhead box B1. (215 aa)    
Predicted Functional Partners:
Otp
Orthopedia homolog (Drosophila), isoform CRA_a.
   
  
 0.712
Foxe1
Forkhead box E1 (Thyroid transcription factor 2).
 
 
  
 0.604
Lhx9
LIM/homeobox protein Lhx9; Involved in gonadal development.
      
 0.559
Nkx1-2
RCG47496, isoform CRA_a.
   
  
 0.549
Sox5
SRY-box transcription factor 5.
      
 0.549
Lhx5
LIM/homeobox protein Lhx5; Plays an essential role in the regulation of neuronal differentiation and migration during development of the central nervous system.
   
  
 0.540
Lhx1
LIM/homeobox protein Lhx1; Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis (By similarity).
   
  
 0.540
Sim1
SIM bHLH transcription factor 1.
   
  
 0.524
Foxr1
Forkhead box R1.
      
 0.504
Foxk2
Forkhead box K2 (Predicted), isoform CRA_a.
      
 0.484
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.