STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rnf208Ring finger protein 208. (265 aa)    
Predicted Functional Partners:
Sertad3
Similar to replication protein-binding trans-activator RBT1.
      
 0.745
Smtnl1
Smoothelin-like 1.
      
 0.697
Pet100
PET100 cytochrome c oxidase chaperone.
      
 0.695
Lilra5
Leukocyte immunoglobulin-like receptor A5.
   
  
 0.663
Gpr160
Probable G-protein coupled receptor 160; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.642
Pmpcb
Mitochondrial-processing peptidase subunit beta; Catalytic subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins (Probable). Preferentially, cleaves after an arginine at position P2. Required for PINK1 turnover by coupling PINK1 mitochondrial import and cleavage, which results in subsequent PINK1 proteolysis ; Belongs to the peptidase M16 family.
    
 
 0.540
Zfp575
RCG54405, isoform CRA_a.
   
 
 0.514
Stpg1
O(6)-methylguanine-induced apoptosis 2; May positively contribute to the induction of apoptosis triggered by O(6)-methylguanine; Belongs to the STPG1 family.
   
  
 0.482
Lpar6
Lysophosphatidic acid receptor 6; Binds to oleoyl-L-alpha-lysophosphatidic acid (LPA). Intracellular cAMP is involved in the receptor activation. Important for the maintenance of hair growth and texture (By similarity). Belongs to the G-protein coupled receptor 1 family.
      
 0.465
Hoxb5
Similar to homeotic protein Hox B5-mouse (Predicted).
    
 
 0.445
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.