STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dbndd1Dysbindin domain-containing protein 1; Belongs to the dysbindin family. (223 aa)    
Predicted Functional Partners:
Fanca
Fanconi anemia, complementation group A (Predicted).
   
  
 0.779
Afg3l1
AFG3(ATPase family gene 3)-like 1 (S. cerevisiae).
   
  
 0.742
Spata33
Spermatogenesis-associated 33.
   
  
 0.705
Vps9d1
VPS9 domain-containing 1.
      
 0.663
RGD1309350
5-hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
      
 0.650
Def8
Differentially expressed in FDCP 8 homolog; Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts. Involved in bone resorption. Belongs to the DEF8 family.
      
 0.643
Mns1
Meiosis-specific nuclear structural protein 1; May play a role in the control of meiotic division and germ cell differentiation through regulation of pairing and recombination during meiosis; Belongs to the MNS1 family.
      
 0.613
Dbndd2
Similar to uncharacterized hypothalamus protein HSMNP1.
      
 0.592
Armc3
Armadillo repeat-containing 3.
      
 0.584
Spink8
Similar to Esophagus cancer-related gene-2 protein (ECRG-2) (Predicted), isoform CRA_a.
      
 0.581
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.