node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Birc2 | Birc3 | ENSRNOP00000014560 | ENSRNOP00000007702 | Baculoviral IAP repeat-containing 2. | Baculoviral IAP repeat-containing 3. | 0.983 |
Birc2 | Casp9 | ENSRNOP00000014560 | ENSRNOP00000017972 | Baculoviral IAP repeat-containing 2. | Caspase 9, isoform CRA_a; Belongs to the peptidase C14A family. | 0.990 |
Birc2 | Diablo | ENSRNOP00000014560 | ENSRNOP00000046476 | Baculoviral IAP repeat-containing 2. | Diablo homolog (Drosophila), isoform CRA_b. | 0.989 |
Birc2 | LOC100360940 | ENSRNOP00000014560 | ENSRNOP00000011308 | Baculoviral IAP repeat-containing 2. | Diablo-like. | 0.989 |
Birc2 | Map3k7 | ENSRNOP00000014560 | ENSRNOP00000007654 | Baculoviral IAP repeat-containing 2. | Mitogen-activated protein kinase kinase kinase 7; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signal transduction of TRAF6, various cytokines including interleukin-1 (IL-1), transforming growth factor-beta (TGFB), TGFB-related factors like BMP2 and BMP4, toll-like receptors (TLR), tumor necrosis factor receptor CD40 and B-cell receptor (BCR). Ceramides are also able to activate MAP3K7/TAK1. Once activated, acts as a [...] | 0.993 |
Birc2 | Ripk1 | ENSRNOP00000014560 | ENSRNOP00000023962 | Baculoviral IAP repeat-containing 2. | Receptor (TNFRSF)-interacting serine-threonine kinase 1 (Predicted). | 0.994 |
Birc2 | Tlr4 | ENSRNOP00000014560 | ENSRNOP00000014020 | Baculoviral IAP repeat-containing 2. | Toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to [...] | 0.983 |
Birc2 | Tradd | ENSRNOP00000014560 | ENSRNOP00000020405 | Baculoviral IAP repeat-containing 2. | TNFRSF1A-associated via death domain. | 0.994 |
Birc2 | Traf2 | ENSRNOP00000014560 | ENSRNOP00000008253 | Baculoviral IAP repeat-containing 2. | TNF receptor-associated factor. | 0.997 |
Birc2 | Traf3 | ENSRNOP00000014560 | ENSRNOP00000074381 | Baculoviral IAP repeat-containing 2. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.992 |
Birc3 | Birc2 | ENSRNOP00000007702 | ENSRNOP00000014560 | Baculoviral IAP repeat-containing 3. | Baculoviral IAP repeat-containing 2. | 0.983 |
Birc3 | Casp9 | ENSRNOP00000007702 | ENSRNOP00000017972 | Baculoviral IAP repeat-containing 3. | Caspase 9, isoform CRA_a; Belongs to the peptidase C14A family. | 0.990 |
Birc3 | Diablo | ENSRNOP00000007702 | ENSRNOP00000046476 | Baculoviral IAP repeat-containing 3. | Diablo homolog (Drosophila), isoform CRA_b. | 0.989 |
Birc3 | LOC100360940 | ENSRNOP00000007702 | ENSRNOP00000011308 | Baculoviral IAP repeat-containing 3. | Diablo-like. | 0.989 |
Birc3 | Map3k7 | ENSRNOP00000007702 | ENSRNOP00000007654 | Baculoviral IAP repeat-containing 3. | Mitogen-activated protein kinase kinase kinase 7; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signal transduction of TRAF6, various cytokines including interleukin-1 (IL-1), transforming growth factor-beta (TGFB), TGFB-related factors like BMP2 and BMP4, toll-like receptors (TLR), tumor necrosis factor receptor CD40 and B-cell receptor (BCR). Ceramides are also able to activate MAP3K7/TAK1. Once activated, acts as a [...] | 0.993 |
Birc3 | Ripk1 | ENSRNOP00000007702 | ENSRNOP00000023962 | Baculoviral IAP repeat-containing 3. | Receptor (TNFRSF)-interacting serine-threonine kinase 1 (Predicted). | 0.994 |
Birc3 | Tlr4 | ENSRNOP00000007702 | ENSRNOP00000014020 | Baculoviral IAP repeat-containing 3. | Toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to [...] | 0.984 |
Birc3 | Tradd | ENSRNOP00000007702 | ENSRNOP00000020405 | Baculoviral IAP repeat-containing 3. | TNFRSF1A-associated via death domain. | 0.994 |
Birc3 | Traf2 | ENSRNOP00000007702 | ENSRNOP00000008253 | Baculoviral IAP repeat-containing 3. | TNF receptor-associated factor. | 0.998 |
Birc3 | Traf3 | ENSRNOP00000007702 | ENSRNOP00000074381 | Baculoviral IAP repeat-containing 3. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.992 |