Ccl5 protein (Rattus norvegicus) - STRING interaction network

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Your Current Organism:

Rattus norvegicus

NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ccl17	Ccl24	ENSRNOP00000021842	ENSRNOP00000056109	C-C motif chemokine.	Chemokine (C-C motif) ligand 24.	0.775
Ccl17	Ccl26	ENSRNOP00000021842	ENSRNOP00000001963	C-C motif chemokine.	C-C motif chemokine ligand 26.	0.968
Ccl17	Ccl27	ENSRNOP00000021842	ENSRNOP00000057330	C-C motif chemokine.	Chemokine (C-C motif) ligand 27 (Predicted), isoform CRA_b.	0.767
Ccl17	Ccl28	ENSRNOP00000021842	ENSRNOP00000074357	C-C motif chemokine.	C-C motif chemokine.	0.936
Ccl17	Ccl5	ENSRNOP00000021842	ENSRNOP00000014865	C-C motif chemokine.	C-C motif chemokine 5; Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells. Belongs to the intercrine beta (chemokine CC) family.	0.996
Ccl17	Ccr1	ENSRNOP00000021842	ENSRNOP00000008772	C-C motif chemokine.	Macrophage inflammatory protein-1 alpha receptor; Belongs to the G-protein coupled receptor 1 family.	0.932
Ccl17	Ccr3	ENSRNOP00000021842	ENSRNOP00000008809	C-C motif chemokine.	C-C chemokine receptor type 3; Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15. Subsequently transduces a signal by increasing the intracellular calcium ions level. In addition acts as a possible functional receptor for NARS1.	0.949
Ccl17	Ccr5	ENSRNOP00000021842	ENSRNOP00000073121	C-C motif chemokine.	C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation (By similarity).	0.955
Ccl17	Cx3cr1	ENSRNOP00000021842	ENSRNOP00000025019	C-C motif chemokine.	CX3C chemokine receptor 1; Receptor for the CX3C chemokine fractalkine (CX3CL1); binds to CX3CL1 and mediates both its adhesive and migratory functions.	0.953
Ccl17	Cxcl10	ENSRNOP00000021842	ENSRNOP00000003649	C-C motif chemokine.	C-X-C motif chemokine 10; Pro-inflammatory cytokine that is involved in a wide variety of processes such as chemotaxis, differentiation, and activation of peripheral immune cells, regulation of cell growth, apoptosis and modulation of angiostatic effects (By similarity). Plays thereby an important role during viral infections by stimulating the activation and migration of immune cells to the infected sites (By similarity). Mechanistically, binding of CXCL10 to the CXCR3 receptor activates G protein-mediated signaling and results in downstream activation of phospholipase C-dependent pat [...]	0.751
Ccl24	Ccl17	ENSRNOP00000056109	ENSRNOP00000021842	Chemokine (C-C motif) ligand 24.	C-C motif chemokine.	0.775
Ccl24	Ccl26	ENSRNOP00000056109	ENSRNOP00000001963	Chemokine (C-C motif) ligand 24.	C-C motif chemokine ligand 26.	0.955
Ccl24	Ccl27	ENSRNOP00000056109	ENSRNOP00000057330	Chemokine (C-C motif) ligand 24.	Chemokine (C-C motif) ligand 27 (Predicted), isoform CRA_b.	0.957
Ccl24	Ccl28	ENSRNOP00000056109	ENSRNOP00000074357	Chemokine (C-C motif) ligand 24.	C-C motif chemokine.	0.919
Ccl24	Ccl5	ENSRNOP00000056109	ENSRNOP00000014865	Chemokine (C-C motif) ligand 24.	C-C motif chemokine 5; Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells. Belongs to the intercrine beta (chemokine CC) family.	0.992
Ccl24	Ccr1	ENSRNOP00000056109	ENSRNOP00000008772	Chemokine (C-C motif) ligand 24.	Macrophage inflammatory protein-1 alpha receptor; Belongs to the G-protein coupled receptor 1 family.	0.908
Ccl24	Ccr3	ENSRNOP00000056109	ENSRNOP00000008809	Chemokine (C-C motif) ligand 24.	C-C chemokine receptor type 3; Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15. Subsequently transduces a signal by increasing the intracellular calcium ions level. In addition acts as a possible functional receptor for NARS1.	0.962
Ccl24	Ccr5	ENSRNOP00000056109	ENSRNOP00000073121	Chemokine (C-C motif) ligand 24.	C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation (By similarity).	0.933
Ccl24	Cx3cr1	ENSRNOP00000056109	ENSRNOP00000025019	Chemokine (C-C motif) ligand 24.	CX3C chemokine receptor 1; Receptor for the CX3C chemokine fractalkine (CX3CL1); binds to CX3CL1 and mediates both its adhesive and migratory functions.	0.943
Ccl24	Cxcl10	ENSRNOP00000056109	ENSRNOP00000003649	Chemokine (C-C motif) ligand 24.	C-X-C motif chemokine 10; Pro-inflammatory cytokine that is involved in a wide variety of processes such as chemotaxis, differentiation, and activation of peripheral immune cells, regulation of cell growth, apoptosis and modulation of angiostatic effects (By similarity). Plays thereby an important role during viral infections by stimulating the activation and migration of immune cells to the infected sites (By similarity). Mechanistically, binding of CXCL10 to the CXCR3 receptor activates G protein-mediated signaling and results in downstream activation of phospholipase C-dependent pat [...]	0.620

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