node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ccl17 | Ccl24 | ENSRNOP00000021842 | ENSRNOP00000056109 | C-C motif chemokine. | Chemokine (C-C motif) ligand 24. | 0.841 |
Ccl17 | Ccl26 | ENSRNOP00000021842 | ENSRNOP00000001963 | C-C motif chemokine. | C-C motif chemokine ligand 26. | 0.985 |
Ccl17 | Ccl27 | ENSRNOP00000021842 | ENSRNOP00000057330 | C-C motif chemokine. | Chemokine (C-C motif) ligand 27 (Predicted), isoform CRA_b. | 0.745 |
Ccl17 | Ccl5 | ENSRNOP00000021842 | ENSRNOP00000014865 | C-C motif chemokine. | C-C motif chemokine 5; Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells. Belongs to the intercrine beta (chemokine CC) family. | 0.998 |
Ccl17 | Ccr1 | ENSRNOP00000021842 | ENSRNOP00000008772 | C-C motif chemokine. | Macrophage inflammatory protein-1 alpha receptor; Belongs to the G-protein coupled receptor 1 family. | 0.923 |
Ccl17 | Ccr3 | ENSRNOP00000021842 | ENSRNOP00000008809 | C-C motif chemokine. | C-C chemokine receptor type 3; Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15. Subsequently transduces a signal by increasing the intracellular calcium ions level. In addition acts as a possible functional receptor for NARS1. | 0.933 |
Ccl17 | Ccr5 | ENSRNOP00000021842 | ENSRNOP00000073121 | C-C motif chemokine. | C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation (By similarity). | 0.957 |
Ccl17 | Cxcl9 | ENSRNOP00000021842 | ENSRNOP00000003627 | C-C motif chemokine. | C-X-C motif chemokine. | 0.813 |
Ccl17 | Cxcr3 | ENSRNOP00000021842 | ENSRNOP00000004406 | C-C motif chemokine. | C-X-C chemokine receptor type 3; Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of mesangial cells through a heterotrimeric G-protein signaling pathway. Binds to CCL21. Probably promotes cell chemotaxis response (By similarity). | 0.908 |
Ccl17 | Pf4 | ENSRNOP00000021842 | ENSRNOP00000032276 | C-C motif chemokine. | Platelet factor 4; Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation; Belongs to the intercrine alpha (chemokine CxC) family. | 0.880 |
Ccl24 | Ccl17 | ENSRNOP00000056109 | ENSRNOP00000021842 | Chemokine (C-C motif) ligand 24. | C-C motif chemokine. | 0.841 |
Ccl24 | Ccl26 | ENSRNOP00000056109 | ENSRNOP00000001963 | Chemokine (C-C motif) ligand 24. | C-C motif chemokine ligand 26. | 0.954 |
Ccl24 | Ccl27 | ENSRNOP00000056109 | ENSRNOP00000057330 | Chemokine (C-C motif) ligand 24. | Chemokine (C-C motif) ligand 27 (Predicted), isoform CRA_b. | 0.976 |
Ccl24 | Ccl5 | ENSRNOP00000056109 | ENSRNOP00000014865 | Chemokine (C-C motif) ligand 24. | C-C motif chemokine 5; Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells. Belongs to the intercrine beta (chemokine CC) family. | 0.997 |
Ccl24 | Ccr1 | ENSRNOP00000056109 | ENSRNOP00000008772 | Chemokine (C-C motif) ligand 24. | Macrophage inflammatory protein-1 alpha receptor; Belongs to the G-protein coupled receptor 1 family. | 0.872 |
Ccl24 | Ccr3 | ENSRNOP00000056109 | ENSRNOP00000008809 | Chemokine (C-C motif) ligand 24. | C-C chemokine receptor type 3; Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15. Subsequently transduces a signal by increasing the intracellular calcium ions level. In addition acts as a possible functional receptor for NARS1. | 0.999 |
Ccl24 | Ccr5 | ENSRNOP00000056109 | ENSRNOP00000073121 | Chemokine (C-C motif) ligand 24. | C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation (By similarity). | 0.813 |
Ccl24 | Cxcl9 | ENSRNOP00000056109 | ENSRNOP00000003627 | Chemokine (C-C motif) ligand 24. | C-X-C motif chemokine. | 0.723 |
Ccl24 | Cxcr3 | ENSRNOP00000056109 | ENSRNOP00000004406 | Chemokine (C-C motif) ligand 24. | C-X-C chemokine receptor type 3; Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of mesangial cells through a heterotrimeric G-protein signaling pathway. Binds to CCL21. Probably promotes cell chemotaxis response (By similarity). | 0.899 |
Ccl24 | Pf4 | ENSRNOP00000056109 | ENSRNOP00000032276 | Chemokine (C-C motif) ligand 24. | Platelet factor 4; Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation; Belongs to the intercrine alpha (chemokine CxC) family. | 0.736 |