STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Spa17Sperm surface protein Sp17; Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates. (148 aa)    
Predicted Functional Partners:
Ropn1
Ropporin-1; Important for male fertility. With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA- dependent signaling processes required for spermatozoa capacitation. Belongs to the ropporin family.
   
 
 0.721
Fhl4
Four and a half LIM domains 4.
    
 
 0.593
Akap4
A-kinase anchor protein 4; Major structural component of sperm fibrous sheath. May play a role in sperm motility (By similarity).
    
 
 0.549
Vsig2
V-set and immunoglobulin domain containing 2 (Predicted).
      
 0.547
Akap3
A kinase (PRKA) anchor protein 3.
    
 
 0.546
Maats1
MYCBP-associated, testis expressed 1.
   
 
 0.540
Tex30
Testis-expressed 30.
   
  
 0.538
Tcte3
T-complex-associated testis-expressed 3.
      
 0.538
Fscb
Fibrous sheath CABYR-binding protein; May be involved in the later stages of fibrous sheath biogenesis. Binds calcium (By similarity).
    
 
 0.523
Tex15
Testis-expressed 15, meiosis and synapsis-associated.
   
 
 0.503
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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