| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Chchd2 | Dnajc13 | ENSRNOP00000065307 | ENSRNOP00000015344 | Coiled-coil-helix-coiled-coil-helix domain-containing protein 2, mitochondrial-like. | DnaJ heat shock protein family (Hsp40) member C13. | 0.707 |
| Chchd2 | Dnajc6 | ENSRNOP00000065307 | ENSRNOP00000070493 | Coiled-coil-helix-coiled-coil-helix domain-containing protein 2, mitochondrial-like. | DnaJ heat shock protein family (Hsp40) member C6. | 0.568 |
| Chchd2 | Eif4g1 | ENSRNOP00000065307 | ENSRNOP00000049629 | Coiled-coil-helix-coiled-coil-helix domain-containing protein 2, mitochondrial-like. | Eukaryotic translation initiation factor 4 gamma, 1. | 0.631 |
| Chchd2 | Fbxo7 | ENSRNOP00000065307 | ENSRNOP00000006366 | Coiled-coil-helix-coiled-coil-helix domain-containing protein 2, mitochondrial-like. | F-box only protein 7; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes BIRC2 and DLGAP5. Plays a role downstream of PINK1 in the clearance of damaged mitochondria via selective autophagy (mitophagy) by targeting PRKN to dysfunctional depolarized mitochondria. Promotes MFN1 ubiquitination (By similarity). | 0.676 |
| Chchd2 | Gak | ENSRNOP00000065307 | ENSRNOP00000000064 | Coiled-coil-helix-coiled-coil-helix domain-containing protein 2, mitochondrial-like. | Cyclin-G-associated kinase; Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1 (By similarity); Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. | 0.518 |
| Chchd2 | Synj1 | ENSRNOP00000065307 | ENSRNOP00000060346 | Coiled-coil-helix-coiled-coil-helix domain-containing protein 2, mitochondrial-like. | Synaptojanin-1; Phosphatase that acts on various phosphoinositides, including phosphatidylinositol 4-phosphate, phosphatidylinositol (4,5)- bisphosphate and phosphatidylinositol (3,4,5)-trisphosphate (By similarity). Has a role in clathrin-mediated endocytosis. Hydrolyzes PIP2 bound to actin regulatory proteins resulting in the rearrangement of actin filaments downstream of tyrosine kinase and ASH/GRB2 (By similarity). | 0.468 |
| Chchd2 | Tmem230 | ENSRNOP00000065307 | ENSRNOP00000028886 | Coiled-coil-helix-coiled-coil-helix domain-containing protein 2, mitochondrial-like. | Transmembrane protein 230; Involved in trafficking and recycling of synaptic vesicles. Belongs to the TMEM134/TMEM230 family. | 0.606 |
| Chchd2 | Vps35 | ENSRNOP00000065307 | ENSRNOP00000024020 | Coiled-coil-helix-coiled-coil-helix domain-containing protein 2, mitochondrial-like. | Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. | 0.746 |
| Dnajc13 | Chchd2 | ENSRNOP00000015344 | ENSRNOP00000065307 | DnaJ heat shock protein family (Hsp40) member C13. | Coiled-coil-helix-coiled-coil-helix domain-containing protein 2, mitochondrial-like. | 0.707 |
| Dnajc13 | Dnajc6 | ENSRNOP00000015344 | ENSRNOP00000070493 | DnaJ heat shock protein family (Hsp40) member C13. | DnaJ heat shock protein family (Hsp40) member C6. | 0.859 |
| Dnajc13 | Eif4g1 | ENSRNOP00000015344 | ENSRNOP00000049629 | DnaJ heat shock protein family (Hsp40) member C13. | Eukaryotic translation initiation factor 4 gamma, 1. | 0.748 |
| Dnajc13 | Fbxo7 | ENSRNOP00000015344 | ENSRNOP00000006366 | DnaJ heat shock protein family (Hsp40) member C13. | F-box only protein 7; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes BIRC2 and DLGAP5. Plays a role downstream of PINK1 in the clearance of damaged mitochondria via selective autophagy (mitophagy) by targeting PRKN to dysfunctional depolarized mitochondria. Promotes MFN1 ubiquitination (By similarity). | 0.713 |
| Dnajc13 | Gak | ENSRNOP00000015344 | ENSRNOP00000000064 | DnaJ heat shock protein family (Hsp40) member C13. | Cyclin-G-associated kinase; Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1 (By similarity); Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. | 0.725 |
| Dnajc13 | Synj1 | ENSRNOP00000015344 | ENSRNOP00000060346 | DnaJ heat shock protein family (Hsp40) member C13. | Synaptojanin-1; Phosphatase that acts on various phosphoinositides, including phosphatidylinositol 4-phosphate, phosphatidylinositol (4,5)- bisphosphate and phosphatidylinositol (3,4,5)-trisphosphate (By similarity). Has a role in clathrin-mediated endocytosis. Hydrolyzes PIP2 bound to actin regulatory proteins resulting in the rearrangement of actin filaments downstream of tyrosine kinase and ASH/GRB2 (By similarity). | 0.713 |
| Dnajc13 | Tmem230 | ENSRNOP00000015344 | ENSRNOP00000028886 | DnaJ heat shock protein family (Hsp40) member C13. | Transmembrane protein 230; Involved in trafficking and recycling of synaptic vesicles. Belongs to the TMEM134/TMEM230 family. | 0.704 |
| Dnajc13 | Vps29 | ENSRNOP00000015344 | ENSRNOP00000068822 | DnaJ heat shock protein family (Hsp40) member C13. | Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans- Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for carg [...] | 0.680 |
| Dnajc13 | Vps35 | ENSRNOP00000015344 | ENSRNOP00000024020 | DnaJ heat shock protein family (Hsp40) member C13. | Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. | 0.887 |
| Dnajc13 | Washc2c | ENSRNOP00000015344 | ENSRNOP00000015620 | DnaJ heat shock protein family (Hsp40) member C13. | WASH complex subunit 2; Acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes inhibits WASH nucleation- promoting factor (NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization and is involved in the fission of tubules that serve as transport intermediates during endosome sorting. Mediates the recruitment of the WASH core complex to endosome membranes via binding to phospholipids and VPS35 of the retromer CSC. Mediates the recruitment of the F-actin-capping protein dimer to the WASH core complex prob [...] | 0.680 |
| Dnajc6 | Chchd2 | ENSRNOP00000070493 | ENSRNOP00000065307 | DnaJ heat shock protein family (Hsp40) member C6. | Coiled-coil-helix-coiled-coil-helix domain-containing protein 2, mitochondrial-like. | 0.568 |
| Dnajc6 | Dnajc13 | ENSRNOP00000070493 | ENSRNOP00000015344 | DnaJ heat shock protein family (Hsp40) member C6. | DnaJ heat shock protein family (Hsp40) member C13. | 0.859 |