Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Blnk | Cd19 | ENSRNOP00000019014 | ENSRNOP00000051906 | B-cell linker protein; Functions as a central linker protein, downstream of the B- cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR- mediated PLCG1 and PLCG2 activation and Ca(2+) mobilization and is required for trafficking of the BCR to late endosomes. However, does not seem to be required for pre-BCR-medi [...] | CD19 molecule. | 0.871 |
| Blnk | Cd22 | ENSRNOP00000019014 | ENSRNOP00000031661 | B-cell linker protein; Functions as a central linker protein, downstream of the B- cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR- mediated PLCG1 and PLCG2 activation and Ca(2+) mobilization and is required for trafficking of the BCR to late endosomes. However, does not seem to be required for pre-BCR-medi [...] | CD22 antigen (Predicted). | 0.554 |
| Blnk | Cd79a | ENSRNOP00000019014 | ENSRNOP00000027254 | B-cell linker protein; Functions as a central linker protein, downstream of the B- cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR- mediated PLCG1 and PLCG2 activation and Ca(2+) mobilization and is required for trafficking of the BCR to late endosomes. However, does not seem to be required for pre-BCR-medi [...] | Ig-like domain-containing protein. | 0.943 |
| Blnk | Cd79al | ENSRNOP00000019014 | ENSRNOP00000066220 | B-cell linker protein; Functions as a central linker protein, downstream of the B- cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR- mediated PLCG1 and PLCG2 activation and Ca(2+) mobilization and is required for trafficking of the BCR to late endosomes. However, does not seem to be required for pre-BCR-medi [...] | Cd79a molecule-like. | 0.890 |
| Blnk | Cd79b | ENSRNOP00000019014 | ENSRNOP00000015977 | B-cell linker protein; Functions as a central linker protein, downstream of the B- cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR- mediated PLCG1 and PLCG2 activation and Ca(2+) mobilization and is required for trafficking of the BCR to late endosomes. However, does not seem to be required for pre-BCR-medi [...] | B29/Ig-beta/CD79b. | 0.918 |
| Blnk | Igll1 | ENSRNOP00000019014 | ENSRNOP00000031750 | B-cell linker protein; Functions as a central linker protein, downstream of the B- cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR- mediated PLCG1 and PLCG2 activation and Ca(2+) mobilization and is required for trafficking of the BCR to late endosomes. However, does not seem to be required for pre-BCR-medi [...] | Immunoglobulin lambda-like polypeptide 1. | 0.810 |
| Blnk | Lyn | ENSRNOP00000019014 | ENSRNOP00000011130 | B-cell linker protein; Functions as a central linker protein, downstream of the B- cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR- mediated PLCG1 and PLCG2 activation and Ca(2+) mobilization and is required for trafficking of the BCR to late endosomes. However, does not seem to be required for pre-BCR-medi [...] | Tyrosine-protein kinase Lyn; Non-receptor tyrosine-protein kinase that transmits signals from cell surface receptors and plays an important role in the regulation of innate and adaptive immune responses, hematopoiesis, responses to growth factors and cytokines, integrin signaling, but also responses to DNA damage and genotoxic agents. Functions primarily as negative regulator, but can also function as activator, depending on the context. Required for the initiation of the B-cell response, but also for its down-regulation and termination. Plays an important role in the regulation of B-c [...] | 0.996 |
| Cd19 | Blnk | ENSRNOP00000051906 | ENSRNOP00000019014 | CD19 molecule. | B-cell linker protein; Functions as a central linker protein, downstream of the B- cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR- mediated PLCG1 and PLCG2 activation and Ca(2+) mobilization and is required for trafficking of the BCR to late endosomes. However, does not seem to be required for pre-BCR-medi [...] | 0.871 |
| Cd19 | Cd22 | ENSRNOP00000051906 | ENSRNOP00000031661 | CD19 molecule. | CD22 antigen (Predicted). | 0.968 |
| Cd19 | Cd79a | ENSRNOP00000051906 | ENSRNOP00000027254 | CD19 molecule. | Ig-like domain-containing protein. | 0.979 |
| Cd19 | Cd79al | ENSRNOP00000051906 | ENSRNOP00000066220 | CD19 molecule. | Cd79a molecule-like. | 0.978 |
| Cd19 | Cd79b | ENSRNOP00000051906 | ENSRNOP00000015977 | CD19 molecule. | B29/Ig-beta/CD79b. | 0.942 |
| Cd19 | Igll1 | ENSRNOP00000051906 | ENSRNOP00000031750 | CD19 molecule. | Immunoglobulin lambda-like polypeptide 1. | 0.720 |
| Cd19 | Jchain | ENSRNOP00000051906 | ENSRNOP00000004866 | CD19 molecule. | Immunoglobulin joining chain. | 0.488 |
| Cd19 | Lyn | ENSRNOP00000051906 | ENSRNOP00000011130 | CD19 molecule. | Tyrosine-protein kinase Lyn; Non-receptor tyrosine-protein kinase that transmits signals from cell surface receptors and plays an important role in the regulation of innate and adaptive immune responses, hematopoiesis, responses to growth factors and cytokines, integrin signaling, but also responses to DNA damage and genotoxic agents. Functions primarily as negative regulator, but can also function as activator, depending on the context. Required for the initiation of the B-cell response, but also for its down-regulation and termination. Plays an important role in the regulation of B-c [...] | 0.994 |
| Cd19 | Ms4a1 | ENSRNOP00000051906 | ENSRNOP00000028433 | CD19 molecule. | Membrane spanning 4-domains A1. | 0.930 |
| Cd22 | Blnk | ENSRNOP00000031661 | ENSRNOP00000019014 | CD22 antigen (Predicted). | B-cell linker protein; Functions as a central linker protein, downstream of the B- cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR- mediated PLCG1 and PLCG2 activation and Ca(2+) mobilization and is required for trafficking of the BCR to late endosomes. However, does not seem to be required for pre-BCR-medi [...] | 0.554 |
| Cd22 | Cd19 | ENSRNOP00000031661 | ENSRNOP00000051906 | CD22 antigen (Predicted). | CD19 molecule. | 0.968 |
| Cd22 | Cd79a | ENSRNOP00000031661 | ENSRNOP00000027254 | CD22 antigen (Predicted). | Ig-like domain-containing protein. | 0.910 |
| Cd22 | Cd79al | ENSRNOP00000031661 | ENSRNOP00000066220 | CD22 antigen (Predicted). | Cd79a molecule-like. | 0.828 |
page 1 of 5