STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
S100a3Protein S100-A3; Binds both calcium and zinc. May be involved in calcium- dependent cuticle cell differentiation, hair shaft and hair cuticular barrier formation (By similarity); Belongs to the S-100 family. (109 aa)    
Predicted Functional Partners:
S100a16
S100 calcium binding protein A16 (Predicted), isoform CRA_a; Belongs to the S-100 family.
   
 
 0.747
Kprp
Keratinocyte proline-rich protein.
   
 
 0.629
S100a13
S100 calcium-binding protein A13; Belongs to the S-100 family.
   
  
0.618
S100a10
Protein S100-A10; Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine-specific kinase.
   
 
 0.615
Tchhl1
EF-hand domain-containing protein.
    
 
 0.600
LOC102554371
Keratin-associated protein 17-1.
  
   
 0.562
Nat14
RCG22702, isoform CRA_a.
      
 0.537
rCG_40975
Small proline-rich protein 4.
      
 0.526
Krt25
Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization (By similarity).
   
 
 0.525
Slc44a2
Choline transporter-like protein 2; Choline transporter; Belongs to the CTL (choline transporter-like) family.
   
  
 0.525
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
Server load: low (24%) [HD]