Tent2 protein (Rattus norvegicus) - STRING interaction network

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Tent2

Poly(A) RNA polymerase GLD2; Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. In contrast to the canonical nuclear poly(A) RNA polymerase, it only adds poly(A) to selected cytoplasmic mRNAs. Does not play a role in replication-dependent histone mRNA degradation. Adds a single nucleotide to the 3' end of specific miRNAs, monoadenylation stabilizes and prolongs the activity of some but not all miRNAs. (484 aa)

Predicted Functional Partners:

Cpeb1

0.938

Papola

0.879

Papolg

0.874

Xrn2

0.809

Sympk

0.808

Cpeb4

0.705

Parn

0.676

Cpeb2

0.676

Cpeb3

0.671

Pgrmc2

0.666

Your Current Organism:

Rattus norvegicus

NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cpeb1	Cpeb2	ENSRNOP00000026009	ENSRNOP00000073259	Cytoplasmic polyadenylation element-binding protein 1; Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the 3'-UTR of mRNAs. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA; a repression that is relieved by phosphorylation or degradat [...]	Cytoplasmic polyadenylation element-binding protein 2.	0.921
Cpeb1	Cpeb3	ENSRNOP00000026009	ENSRNOP00000040393	Cytoplasmic polyadenylation element-binding protein 1; Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the 3'-UTR of mRNAs. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA; a repression that is relieved by phosphorylation or degradat [...]	Cytoplasmic polyadenylation element-binding protein 3.	0.854
Cpeb1	Cpeb4	ENSRNOP00000026009	ENSRNOP00000072827	Cytoplasmic polyadenylation element-binding protein 1; Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the 3'-UTR of mRNAs. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA; a repression that is relieved by phosphorylation or degradat [...]	Cytoplasmic polyadenylation element-binding protein 4.	0.929
Cpeb1	Papola	ENSRNOP00000026009	ENSRNOP00000071393	Cytoplasmic polyadenylation element-binding protein 1; Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the 3'-UTR of mRNAs. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA; a repression that is relieved by phosphorylation or degradat [...]	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.	0.755
Cpeb1	Papolg	ENSRNOP00000026009	ENSRNOP00000008919	Cytoplasmic polyadenylation element-binding protein 1; Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the 3'-UTR of mRNAs. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA; a repression that is relieved by phosphorylation or degradat [...]	Poly(A) polymerase gamma (Predicted).	0.761
Cpeb1	Parn	ENSRNOP00000026009	ENSRNOP00000072539	Cytoplasmic polyadenylation element-binding protein 1; Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the 3'-UTR of mRNAs. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA; a repression that is relieved by phosphorylation or degradat [...]	Poly(A)-specific ribonuclease.	0.689
Cpeb1	Sympk	ENSRNOP00000026009	ENSRNOP00000019814	Cytoplasmic polyadenylation element-binding protein 1; Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the 3'-UTR of mRNAs. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA; a repression that is relieved by phosphorylation or degradat [...]	Symplekin.	0.942
Cpeb1	Tent2	ENSRNOP00000026009	ENSRNOP00000016135	Cytoplasmic polyadenylation element-binding protein 1; Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the 3'-UTR of mRNAs. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA; a repression that is relieved by phosphorylation or degradat [...]	Poly(A) RNA polymerase GLD2; Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. In contrast to the canonical nuclear poly(A) RNA polymerase, it only adds poly(A) to selected cytoplasmic mRNAs. Does not play a role in replication-dependent histone mRNA degradation. Adds a single nucleotide to the 3' end of specific miRNAs, monoadenylation stabilizes and prolongs the activity of some but not all miRNAs.	0.938
Cpeb2	Cpeb1	ENSRNOP00000073259	ENSRNOP00000026009	Cytoplasmic polyadenylation element-binding protein 2.	Cytoplasmic polyadenylation element-binding protein 1; Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the 3'-UTR of mRNAs. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA; a repression that is relieved by phosphorylation or degradat [...]	0.921
Cpeb2	Cpeb3	ENSRNOP00000073259	ENSRNOP00000040393	Cytoplasmic polyadenylation element-binding protein 2.	Cytoplasmic polyadenylation element-binding protein 3.	0.995
Cpeb2	Cpeb4	ENSRNOP00000073259	ENSRNOP00000072827	Cytoplasmic polyadenylation element-binding protein 2.	Cytoplasmic polyadenylation element-binding protein 4.	0.995
Cpeb2	Papola	ENSRNOP00000073259	ENSRNOP00000071393	Cytoplasmic polyadenylation element-binding protein 2.	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.	0.489
Cpeb2	Papolg	ENSRNOP00000073259	ENSRNOP00000008919	Cytoplasmic polyadenylation element-binding protein 2.	Poly(A) polymerase gamma (Predicted).	0.486
Cpeb2	Sympk	ENSRNOP00000073259	ENSRNOP00000019814	Cytoplasmic polyadenylation element-binding protein 2.	Symplekin.	0.633
Cpeb2	Tent2	ENSRNOP00000073259	ENSRNOP00000016135	Cytoplasmic polyadenylation element-binding protein 2.	Poly(A) RNA polymerase GLD2; Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. In contrast to the canonical nuclear poly(A) RNA polymerase, it only adds poly(A) to selected cytoplasmic mRNAs. Does not play a role in replication-dependent histone mRNA degradation. Adds a single nucleotide to the 3' end of specific miRNAs, monoadenylation stabilizes and prolongs the activity of some but not all miRNAs.	0.676
Cpeb3	Cpeb1	ENSRNOP00000040393	ENSRNOP00000026009	Cytoplasmic polyadenylation element-binding protein 3.	Cytoplasmic polyadenylation element-binding protein 1; Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the 3'-UTR of mRNAs. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA; a repression that is relieved by phosphorylation or degradat [...]	0.854
Cpeb3	Cpeb2	ENSRNOP00000040393	ENSRNOP00000073259	Cytoplasmic polyadenylation element-binding protein 3.	Cytoplasmic polyadenylation element-binding protein 2.	0.995
Cpeb3	Cpeb4	ENSRNOP00000040393	ENSRNOP00000072827	Cytoplasmic polyadenylation element-binding protein 3.	Cytoplasmic polyadenylation element-binding protein 4.	0.995
Cpeb3	Papola	ENSRNOP00000040393	ENSRNOP00000071393	Cytoplasmic polyadenylation element-binding protein 3.	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.	0.454
Cpeb3	Papolg	ENSRNOP00000040393	ENSRNOP00000008919	Cytoplasmic polyadenylation element-binding protein 3.	Poly(A) polymerase gamma (Predicted).	0.459

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