STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Haus4Similar to chromosome 14 open reading frame 94, isoform CRA_a. (363 aa)    
Predicted Functional Partners:
Haus3
Similar to EEA1 (Early Endosome Antigen, Rab effector) homolog family member (Eea-1).
   
 0.976
Haus7
Similar to UCH37-interacting protein 1 (Predicted), isoform CRA_b.
   
 0.976
Haus6
HAUS augmin-like complex, subunit 6.
   
 0.976
Haus8
HAUS augmin-like complex subunit 8; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.
   
 0.974
LOC108348136
HAUS augmin-like complex subunit 1; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.
  
 0.971
Haus1
HAUS augmin-like complex, subunit 1.
  
 0.960
Haus5
HAUS augmin-like complex, subunit 5.
   
 0.954
Rbm42
RNA-binding protein 42; Binds (via the RRM domain) to the 3' untranslated region (UTR) of p21 mRNA.
   
 
 0.778
Nek2
NIMA (never in mitosis gene a)-related kinase 2-like 1.
   
 
 0.701
Plk1
Serine/threonine-protein kinase PLK1; Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of anaphase- promoting complex/cyclosome (APC/C) inhibitors, and the regulation of mitotic exit and cytokinesis. Polo-like kinase proteins acts by binding and phosphorylating proteins are that already phosphorylated on a specific motif recognized by the POLO box domains. Phosphorylates BORA, BUB1B/BUBR1, C [...]
   
 
 0.668
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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