Tbxt protein (Rattus norvegicus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Rattus norvegicus

NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Bmp4	Gata3	ENSRNOP00000012957	ENSRNOP00000026187	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).	GATA-binding protein 3.	0.468
Bmp4	Mixl1	ENSRNOP00000012957	ENSRNOP00000004244	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).	Mix paired-like homeobox 1.	0.543
Bmp4	Mixl1-2	ENSRNOP00000012957	ENSRNOP00000064882	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).	Mix paired-like homeobox.	0.547
Bmp4	Nanog	ENSRNOP00000012957	ENSRNOP00000063016	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).	Nanog homeobox.	0.768
Bmp4	Pou5f1	ENSRNOP00000012957	ENSRNOP00000065216	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).	POU domain protein.	0.557
Bmp4	Sox17	ENSRNOP00000012957	ENSRNOP00000033962	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).	SRY-box containing gene 17 (Predicted), isoform CRA_a.	0.754
Bmp4	Tbxt	ENSRNOP00000012957	ENSRNOP00000016471	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).	T, brachyury homolog (Mouse) (Predicted), isoform CRA_b.	0.598
Bmp4	Tfap2a	ENSRNOP00000012957	ENSRNOP00000040925	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).	Transcription factor AP-2-alpha; Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and c-Myc. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITE [...]	0.426
Gata3	Bmp4	ENSRNOP00000026187	ENSRNOP00000012957	GATA-binding protein 3.	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).	0.468
Gata3	Nanog	ENSRNOP00000026187	ENSRNOP00000063016	GATA-binding protein 3.	Nanog homeobox.	0.491
Gata3	Pou5f1	ENSRNOP00000026187	ENSRNOP00000065216	GATA-binding protein 3.	POU domain protein.	0.419
Gata3	Sox17	ENSRNOP00000026187	ENSRNOP00000033962	GATA-binding protein 3.	SRY-box containing gene 17 (Predicted), isoform CRA_a.	0.488
Gata3	Tbxt	ENSRNOP00000026187	ENSRNOP00000016471	GATA-binding protein 3.	T, brachyury homolog (Mouse) (Predicted), isoform CRA_b.	0.580
Gata3	Tfap2a	ENSRNOP00000026187	ENSRNOP00000040925	GATA-binding protein 3.	Transcription factor AP-2-alpha; Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and c-Myc. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITE [...]	0.543
M0R9G4_RAT	Rin3	ENSRNOP00000066132	ENSRNOP00000071441	Uncharacterized protein.	Ras and Rab interactor 3.	0.570
M0R9G4_RAT	Tbxt	ENSRNOP00000066132	ENSRNOP00000016471	Uncharacterized protein.	T, brachyury homolog (Mouse) (Predicted), isoform CRA_b.	0.576
Mixl1	Bmp4	ENSRNOP00000004244	ENSRNOP00000012957	Mix paired-like homeobox 1.	Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).	0.543
Mixl1	Nanog	ENSRNOP00000004244	ENSRNOP00000063016	Mix paired-like homeobox 1.	Nanog homeobox.	0.769
Mixl1	Pou5f1	ENSRNOP00000004244	ENSRNOP00000065216	Mix paired-like homeobox 1.	POU domain protein.	0.500
Mixl1	Sox17	ENSRNOP00000004244	ENSRNOP00000033962	Mix paired-like homeobox 1.	SRY-box containing gene 17 (Predicted), isoform CRA_a.	0.825

page 1 of 4

Server load: low (16%) [HD]

Share

Network

Co-occurrence

Experiments

Co-expression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About