STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
St6galnac2ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2; Belongs to the glycosyltransferase 29 family. (373 aa)    
Predicted Functional Partners:
Defb39
Beta-defensin 39; Has antibacterial activity; Belongs to the beta-defensin family.
      
 0.660
Defb18
Beta-defensin 18; Has antibacterial activity; Belongs to the beta-defensin family.
      
 0.581
St6galnac5
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5; Belongs to the glycosyltransferase 29 family.
  
   
0.573
C1galt1c1
C1GALT1-specific chaperone 1; Probable chaperone required for the generation of 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Probably acts as a specific molecular chaperone assisting the folding/stability of core 1 beta-3- galactosyltransferase (C1GALT1) (By similarity).
    
 
 0.571
C1galt1
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1; Glycosyltransferase that generates the core 1 O-glycan Gal- beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development.
    
 
 0.568
Trmt11
tRNA (guanine(10)-N2)-methyltransferase homolog; Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.
      
 0.535
St6galnac6
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6; Belongs to the glycosyltransferase 29 family.
      
 0.534
Ube3d
E3 ubiquitin-protein ligase E3D; E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
      
 0.533
A0A0G2K8V8_RAT
Uncharacterized protein.
      
 0.529
Gcnt1
Enzymatic glycosylation-regulating gene protein.
   
  
 0.514
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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