| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cs | Csnk2a1 | ENSRNOP00000034921 | ENSRNOP00000007558 | Citrate synthase, mitochondrial. | Casein kinase II subunit alpha; Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response. During mitosis, functions as a component of the p53/TP53-dependent spindle assembly checkpoin [...] | 0.628 |
| Cs | Csnk2a2 | ENSRNOP00000034921 | ENSRNOP00000016386 | Citrate synthase, mitochondrial. | Casein kinase 2, alpha prime polypeptide; Belongs to the protein kinase superfamily. | 0.627 |
| Cs | Drg1 | ENSRNOP00000034921 | ENSRNOP00000025241 | Citrate synthase, mitochondrial. | Developmentally-regulated GTP-binding protein 1. | 0.727 |
| Cs | Drg2 | ENSRNOP00000034921 | ENSRNOP00000075413 | Citrate synthase, mitochondrial. | Developmentally-regulated GTP-binding protein 2. | 0.598 |
| Cs | Grn | ENSRNOP00000034921 | ENSRNOP00000028557 | Citrate synthase, mitochondrial. | Paragranulin; Secreted protein that acts as a key regulator of lysosomal function and as a growth factor involved in inflammation, wound healing and cell proliferation (By similarity). Regulates protein trafficking to lysosomes and, also the activity of lysosomal enzymes (By similarity). Facilitates also the acidification of lysosomes, causing degradation of mature CTSD by CTSB (By similarity). In addition, functions as wound-related growth factor that acts directly on dermal fibroblasts and endothelial cells to promote division, migration and the formation of capillary-like tubule str [...] | 0.746 |
| Cs | Pole2 | ENSRNOP00000034921 | ENSRNOP00000005835 | Citrate synthase, mitochondrial. | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. | 0.727 |
| Cs | RGD1564541 | ENSRNOP00000034921 | ENSRNOP00000016993 | Citrate synthase, mitochondrial. | Similar to hypothetical protein FLJ22965. | 0.727 |
| Cs | Slc25a1 | ENSRNOP00000034921 | ENSRNOP00000000306 | Citrate synthase, mitochondrial. | Tricarboxylate transport protein, mitochondrial; Citrate transporter that mediates the exchange of mitochondrial citrate for cytosolic malate. Also able to mediate the exchange of citrate for isocitrate, phosphoenolpyruvate, cis- but not trans-aconitate and to a lesser extend maleate and succinate. Important for the bioenergetics of hepatic cells as it provides a carbon source for fatty acid and sterol biosyntheses, and NAD(+) for the glycolytic pathway. Required for proper neuromuscular junction formation. Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.956 |
| Csnk2a1 | Cs | ENSRNOP00000007558 | ENSRNOP00000034921 | Casein kinase II subunit alpha; Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response. During mitosis, functions as a component of the p53/TP53-dependent spindle assembly checkpoin [...] | Citrate synthase, mitochondrial. | 0.628 |
| Csnk2a1 | Csnk2a2 | ENSRNOP00000007558 | ENSRNOP00000016386 | Casein kinase II subunit alpha; Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response. During mitosis, functions as a component of the p53/TP53-dependent spindle assembly checkpoin [...] | Casein kinase 2, alpha prime polypeptide; Belongs to the protein kinase superfamily. | 0.966 |
| Csnk2a1 | Drg1 | ENSRNOP00000007558 | ENSRNOP00000025241 | Casein kinase II subunit alpha; Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response. During mitosis, functions as a component of the p53/TP53-dependent spindle assembly checkpoin [...] | Developmentally-regulated GTP-binding protein 1. | 0.624 |
| Csnk2a1 | Drg2 | ENSRNOP00000007558 | ENSRNOP00000075413 | Casein kinase II subunit alpha; Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response. During mitosis, functions as a component of the p53/TP53-dependent spindle assembly checkpoin [...] | Developmentally-regulated GTP-binding protein 2. | 0.516 |
| Csnk2a1 | Grn | ENSRNOP00000007558 | ENSRNOP00000028557 | Casein kinase II subunit alpha; Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response. During mitosis, functions as a component of the p53/TP53-dependent spindle assembly checkpoin [...] | Paragranulin; Secreted protein that acts as a key regulator of lysosomal function and as a growth factor involved in inflammation, wound healing and cell proliferation (By similarity). Regulates protein trafficking to lysosomes and, also the activity of lysosomal enzymes (By similarity). Facilitates also the acidification of lysosomes, causing degradation of mature CTSD by CTSB (By similarity). In addition, functions as wound-related growth factor that acts directly on dermal fibroblasts and endothelial cells to promote division, migration and the formation of capillary-like tubule str [...] | 0.598 |
| Csnk2a1 | Pole2 | ENSRNOP00000007558 | ENSRNOP00000005835 | Casein kinase II subunit alpha; Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response. During mitosis, functions as a component of the p53/TP53-dependent spindle assembly checkpoin [...] | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. | 0.598 |
| Csnk2a1 | RGD1564541 | ENSRNOP00000007558 | ENSRNOP00000016993 | Casein kinase II subunit alpha; Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response. During mitosis, functions as a component of the p53/TP53-dependent spindle assembly checkpoin [...] | Similar to hypothetical protein FLJ22965. | 0.600 |
| Csnk2a1 | Slc25a1 | ENSRNOP00000007558 | ENSRNOP00000000306 | Casein kinase II subunit alpha; Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response. During mitosis, functions as a component of the p53/TP53-dependent spindle assembly checkpoin [...] | Tricarboxylate transport protein, mitochondrial; Citrate transporter that mediates the exchange of mitochondrial citrate for cytosolic malate. Also able to mediate the exchange of citrate for isocitrate, phosphoenolpyruvate, cis- but not trans-aconitate and to a lesser extend maleate and succinate. Important for the bioenergetics of hepatic cells as it provides a carbon source for fatty acid and sterol biosyntheses, and NAD(+) for the glycolytic pathway. Required for proper neuromuscular junction formation. Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.600 |
| Csnk2a2 | Cs | ENSRNOP00000016386 | ENSRNOP00000034921 | Casein kinase 2, alpha prime polypeptide; Belongs to the protein kinase superfamily. | Citrate synthase, mitochondrial. | 0.627 |
| Csnk2a2 | Csnk2a1 | ENSRNOP00000016386 | ENSRNOP00000007558 | Casein kinase 2, alpha prime polypeptide; Belongs to the protein kinase superfamily. | Casein kinase II subunit alpha; Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response. During mitosis, functions as a component of the p53/TP53-dependent spindle assembly checkpoin [...] | 0.966 |
| Csnk2a2 | Drg1 | ENSRNOP00000016386 | ENSRNOP00000025241 | Casein kinase 2, alpha prime polypeptide; Belongs to the protein kinase superfamily. | Developmentally-regulated GTP-binding protein 1. | 0.608 |
| Csnk2a2 | Drg2 | ENSRNOP00000016386 | ENSRNOP00000075413 | Casein kinase 2, alpha prime polypeptide; Belongs to the protein kinase superfamily. | Developmentally-regulated GTP-binding protein 2. | 0.516 |