node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dennd3 | Dennd5a | ENSRNOP00000014542 | ENSRNOP00000017485 | DENN domain-containing 3. | DENN domain-containing protein 5A; Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form (By similarity). Involved in the negative regulation of neurite outgrowth. | 0.577 |
Dennd3 | Rab28 | ENSRNOP00000014542 | ENSRNOP00000071725 | DENN domain-containing 3. | Ras-related protein Rab-28; Belongs to the small GTPase superfamily. Rab family. | 0.599 |
Dennd4c | Dennd5a | ENSRNOP00000071348 | ENSRNOP00000017485 | DENN domain-containing 4C. | DENN domain-containing protein 5A; Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form (By similarity). Involved in the negative regulation of neurite outgrowth. | 0.746 |
Dennd4c | Rab28 | ENSRNOP00000071348 | ENSRNOP00000071725 | DENN domain-containing 4C. | Ras-related protein Rab-28; Belongs to the small GTPase superfamily. Rab family. | 0.434 |
Dennd4c | Snx2 | ENSRNOP00000071348 | ENSRNOP00000051352 | DENN domain-containing 4C. | Sorting nexin 2. | 0.775 |
Dennd5a | Dennd3 | ENSRNOP00000017485 | ENSRNOP00000014542 | DENN domain-containing protein 5A; Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form (By similarity). Involved in the negative regulation of neurite outgrowth. | DENN domain-containing 3. | 0.577 |
Dennd5a | Dennd4c | ENSRNOP00000017485 | ENSRNOP00000071348 | DENN domain-containing protein 5A; Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form (By similarity). Involved in the negative regulation of neurite outgrowth. | DENN domain-containing 4C. | 0.746 |
Dennd5a | Get4 | ENSRNOP00000017485 | ENSRNOP00000001745 | DENN domain-containing protein 5A; Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form (By similarity). Involved in the negative regulation of neurite outgrowth. | Guided entry of tail-anchored proteins factor 4. | 0.572 |
Dennd5a | Prrt1 | ENSRNOP00000017485 | ENSRNOP00000000495 | DENN domain-containing protein 5A; Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form (By similarity). Involved in the negative regulation of neurite outgrowth. | Proline-rich transmembrane protein 1. | 0.556 |
Dennd5a | Rab11a | ENSRNOP00000017485 | ENSRNOP00000015598 | DENN domain-containing protein 5A; Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form (By similarity). Involved in the negative regulation of neurite outgrowth. | Ras-related protein Rab-11A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The small Rab GTPase RAB11A regulates endocytic recycling. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial c [...] | 0.798 |
Dennd5a | Rab28 | ENSRNOP00000017485 | ENSRNOP00000071725 | DENN domain-containing protein 5A; Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form (By similarity). Involved in the negative regulation of neurite outgrowth. | Ras-related protein Rab-28; Belongs to the small GTPase superfamily. Rab family. | 0.644 |
Dennd5a | Rab6a | ENSRNOP00000017485 | ENSRNOP00000025104 | DENN domain-containing protein 5A; Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form (By similarity). Involved in the negative regulation of neurite outgrowth. | Ras-related protein Rab-6A; Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER). Involved in COPI-independent retrograde transport from the Golgi to the ER. Belongs to the small GTPase superfamily. Rab family. | 0.994 |
Dennd5a | Rab6b | ENSRNOP00000017485 | ENSRNOP00000068600 | DENN domain-containing protein 5A; Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form (By similarity). Involved in the negative regulation of neurite outgrowth. | RAB6B, member RAS oncogene family. | 0.622 |
Dennd5a | Snx2 | ENSRNOP00000017485 | ENSRNOP00000051352 | DENN domain-containing protein 5A; Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form (By similarity). Involved in the negative regulation of neurite outgrowth. | Sorting nexin 2. | 0.658 |
Dennd5a | Ybey | ENSRNOP00000017485 | ENSRNOP00000030496 | DENN domain-containing protein 5A; Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form (By similarity). Involved in the negative regulation of neurite outgrowth. | Similar to RIKEN cDNA A130042E20; open reading frame 57 (Predicted). | 0.558 |
Get4 | Dennd5a | ENSRNOP00000001745 | ENSRNOP00000017485 | Guided entry of tail-anchored proteins factor 4. | DENN domain-containing protein 5A; Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form (By similarity). Involved in the negative regulation of neurite outgrowth. | 0.572 |
Prrt1 | Dennd5a | ENSRNOP00000000495 | ENSRNOP00000017485 | Proline-rich transmembrane protein 1. | DENN domain-containing protein 5A; Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form (By similarity). Involved in the negative regulation of neurite outgrowth. | 0.556 |
Prrt1 | Ybey | ENSRNOP00000000495 | ENSRNOP00000030496 | Proline-rich transmembrane protein 1. | Similar to RIKEN cDNA A130042E20; open reading frame 57 (Predicted). | 0.467 |
Rab11a | Dennd5a | ENSRNOP00000015598 | ENSRNOP00000017485 | Ras-related protein Rab-11A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The small Rab GTPase RAB11A regulates endocytic recycling. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial c [...] | DENN domain-containing protein 5A; Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form (By similarity). Involved in the negative regulation of neurite outgrowth. | 0.798 |
Rab11a | Rab6a | ENSRNOP00000015598 | ENSRNOP00000025104 | Ras-related protein Rab-11A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The small Rab GTPase RAB11A regulates endocytic recycling. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial c [...] | Ras-related protein Rab-6A; Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER). Involved in COPI-independent retrograde transport from the Golgi to the ER. Belongs to the small GTPase superfamily. Rab family. | 0.694 |