node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ciao1 | Ciao2a | ENSRNOP00000017603 | ENSRNOP00000022999 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (By similarity). As a CIA complex component, interacts specifically with CIAO2A or CIAO2B and MMS19 to assist different branches of iron-sulfur protein assembly, depending of its interactors. The complex CIAO1:CIAO2B:MMS19 binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins. CIAO1:CIAO2A specifically matures AC [...] | Similar to RIKEN cDNA 5730536A07, isoform CRA_a. | 0.987 |
Ciao1 | Ciao2b | ENSRNOP00000017603 | ENSRNOP00000015811 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (By similarity). As a CIA complex component, interacts specifically with CIAO2A or CIAO2B and MMS19 to assist different branches of iron-sulfur protein assembly, depending of its interactors. The complex CIAO1:CIAO2B:MMS19 binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins. CIAO1:CIAO2A specifically matures AC [...] | Cytosolic iron-sulfur assembly component 2B. | 0.999 |
Ciao1 | Ciao3 | ENSRNOP00000017603 | ENSRNOP00000026518 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (By similarity). As a CIA complex component, interacts specifically with CIAO2A or CIAO2B and MMS19 to assist different branches of iron-sulfur protein assembly, depending of its interactors. The complex CIAO1:CIAO2B:MMS19 binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins. CIAO1:CIAO2A specifically matures AC [...] | Cytosolic iron-sulfur assembly component 3; Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to negatively regulate the level of HIF1A expression, although this effect could be indirect (By similarity); Belongs to the NARF family. | 0.972 |
Ciao1 | Ciapin1 | ENSRNOP00000017603 | ENSRNOP00000021769 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (By similarity). As a CIA complex component, interacts specifically with CIAO2A or CIAO2B and MMS19 to assist different branches of iron-sulfur protein assembly, depending of its interactors. The complex CIAO1:CIAO2B:MMS19 binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins. CIAO1:CIAO2A specifically matures AC [...] | Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...] | 0.778 |
Ciao1 | Ercc2 | ENSRNOP00000017603 | ENSRNOP00000024247 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (By similarity). As a CIA complex component, interacts specifically with CIAO2A or CIAO2B and MMS19 to assist different branches of iron-sulfur protein assembly, depending of its interactors. The complex CIAO1:CIAO2B:MMS19 binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins. CIAO1:CIAO2A specifically matures AC [...] | ERCC excision repair 2, TFIIH core complex helicase subunit. | 0.922 |
Ciao1 | Mms19 | ENSRNOP00000017603 | ENSRNOP00000065140 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (By similarity). As a CIA complex component, interacts specifically with CIAO2A or CIAO2B and MMS19 to assist different branches of iron-sulfur protein assembly, depending of its interactors. The complex CIAO1:CIAO2B:MMS19 binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins. CIAO1:CIAO2A specifically matures AC [...] | MMS19 homolog, cytosolic iron-sulfur assembly component. | 0.998 |
Ciao1 | Narf | ENSRNOP00000017603 | ENSRNOP00000051803 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (By similarity). As a CIA complex component, interacts specifically with CIAO2A or CIAO2B and MMS19 to assist different branches of iron-sulfur protein assembly, depending of its interactors. The complex CIAO1:CIAO2B:MMS19 binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins. CIAO1:CIAO2A specifically matures AC [...] | Nuclear prelamin A recognition factor; Belongs to the NARF family. | 0.706 |
Ciao1 | Nubpl | ENSRNOP00000017603 | ENSRNOP00000029049 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (By similarity). As a CIA complex component, interacts specifically with CIAO2A or CIAO2B and MMS19 to assist different branches of iron-sulfur protein assembly, depending of its interactors. The complex CIAO1:CIAO2B:MMS19 binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins. CIAO1:CIAO2A specifically matures AC [...] | Nucleotide-binding protein-like. | 0.684 |
Ciao1 | Slc25a5 | ENSRNOP00000017603 | ENSRNOP00000015913 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (By similarity). As a CIA complex component, interacts specifically with CIAO2A or CIAO2B and MMS19 to assist different branches of iron-sulfur protein assembly, depending of its interactors. The complex CIAO1:CIAO2B:MMS19 binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins. CIAO1:CIAO2A specifically matures AC [...] | ADP/ATP translocase 2, N-terminally processed; Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation (By similarity); Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.927 |
Ciao1 | Zmynd12 | ENSRNOP00000017603 | ENSRNOP00000068269 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (By similarity). As a CIA complex component, interacts specifically with CIAO2A or CIAO2B and MMS19 to assist different branches of iron-sulfur protein assembly, depending of its interactors. The complex CIAO1:CIAO2B:MMS19 binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins. CIAO1:CIAO2A specifically matures AC [...] | Zinc finger, MYND-type-containing 12. | 0.717 |
Ciao2a | Ciao1 | ENSRNOP00000022999 | ENSRNOP00000017603 | Similar to RIKEN cDNA 5730536A07, isoform CRA_a. | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (By similarity). As a CIA complex component, interacts specifically with CIAO2A or CIAO2B and MMS19 to assist different branches of iron-sulfur protein assembly, depending of its interactors. The complex CIAO1:CIAO2B:MMS19 binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins. CIAO1:CIAO2A specifically matures AC [...] | 0.987 |
Ciao2a | Ciao2b | ENSRNOP00000022999 | ENSRNOP00000015811 | Similar to RIKEN cDNA 5730536A07, isoform CRA_a. | Cytosolic iron-sulfur assembly component 2B. | 0.788 |
Ciao2a | Ciao3 | ENSRNOP00000022999 | ENSRNOP00000026518 | Similar to RIKEN cDNA 5730536A07, isoform CRA_a. | Cytosolic iron-sulfur assembly component 3; Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to negatively regulate the level of HIF1A expression, although this effect could be indirect (By similarity); Belongs to the NARF family. | 0.879 |
Ciao2a | Ciapin1 | ENSRNOP00000022999 | ENSRNOP00000021769 | Similar to RIKEN cDNA 5730536A07, isoform CRA_a. | Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...] | 0.435 |
Ciao2a | Ercc2 | ENSRNOP00000022999 | ENSRNOP00000024247 | Similar to RIKEN cDNA 5730536A07, isoform CRA_a. | ERCC excision repair 2, TFIIH core complex helicase subunit. | 0.671 |
Ciao2a | Mms19 | ENSRNOP00000022999 | ENSRNOP00000065140 | Similar to RIKEN cDNA 5730536A07, isoform CRA_a. | MMS19 homolog, cytosolic iron-sulfur assembly component. | 0.966 |
Ciao2a | Narf | ENSRNOP00000022999 | ENSRNOP00000051803 | Similar to RIKEN cDNA 5730536A07, isoform CRA_a. | Nuclear prelamin A recognition factor; Belongs to the NARF family. | 0.590 |
Ciao2b | Ciao1 | ENSRNOP00000015811 | ENSRNOP00000017603 | Cytosolic iron-sulfur assembly component 2B. | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (By similarity). As a CIA complex component, interacts specifically with CIAO2A or CIAO2B and MMS19 to assist different branches of iron-sulfur protein assembly, depending of its interactors. The complex CIAO1:CIAO2B:MMS19 binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins. CIAO1:CIAO2A specifically matures AC [...] | 0.999 |
Ciao2b | Ciao2a | ENSRNOP00000015811 | ENSRNOP00000022999 | Cytosolic iron-sulfur assembly component 2B. | Similar to RIKEN cDNA 5730536A07, isoform CRA_a. | 0.788 |
Ciao2b | Ciao3 | ENSRNOP00000015811 | ENSRNOP00000026518 | Cytosolic iron-sulfur assembly component 2B. | Cytosolic iron-sulfur assembly component 3; Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to negatively regulate the level of HIF1A expression, although this effect could be indirect (By similarity); Belongs to the NARF family. | 0.939 |